2,3-二氯-2-甲基丙酰胺 | 7017-20-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2,3-二氯-2-甲基丙酰胺
• 英文名称: 2,3-Dichloro-2-methylpropanamide
• 英文别名: α,β-dichloro-isobutyric acid amide；α,β-Dichlor-isobuttersaeure-amid；methacrylamide chloride；2,3-Dichlor-2-methylpropionamid
• CAS: 7017-20-1
• 化学式: C₄H₇Cl₂NO
• mdl: MFCD19232300
• 分子量: 156.012
• InChiKey: KVIZYHWPRCTUGZ-UHFFFAOYSA-N

物化性质

• 熔点：
  65-66 °C
• 沸点：
  285.4±25.0 °C(Predicted)
• 密度：
  1.320±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  43.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2,3-二氯-2-甲基丙酰胺 在 五氯化磷 作用下， 以 苯 为溶剂， 生成
  参考文献：
  名称：

  Rudavskii,V.P.; Kondratenko,V.I., Journal of general chemistry of the USSR, 1971, vol. 41, p. 2176 - 2179

  摘要：

  DOI：
• 作为产物：
  描述：

  甲基丙烯酰胺 在 氯 作用下， 以 溶剂黄146 为溶剂， 生成 2,3-二氯-2-甲基丙酰胺
  参考文献：
  名称：

  Kinetics and mechanism of chlorine addition to acrylic acid and its derivatives with special reference to the nature of the transition state

  摘要：

  DOI：

  10.1021/jo01294a051

文献信息

• PACKAGING SOLUTIONS
  申请人：Schorzman Derek A.

  公开号：US20080152540A1

  公开（公告）日：2008-06-26

  The present invention is directed to new and improved packaging systems for storing cationic ophthalmic devices such as cationic contact lenses and to methods for packaging such cationic ophthalmic devices with solutions to improve the comfort of the lenses during wear. In particular, the present invention is directed to a packaging system for storing a cationic ophthalmic device in a solution comprising an effective amount of an anionic polymer. Such solutions are retained on the surface of an unused lens for extended periods of time, resulting in surface modification that persists in the eye, which may provide significant improvement in the wetting properties of fresh lenses used for the first time and, moreover, even several hours after lens insertion, preventing dryness and improving lubricity.

  本发明涉及新的和改进的包装系统，用于存储阳离子眼科设备，例如阳离子隐形眼镜，并提供包装这些阳离子眼科设备的方法，以改善佩戴隐形眼镜时的舒适度。具体而言，本发明涉及一种包装系统，用于在包含一定量阴离子聚合物的溶液中存储阳离子眼科设备。这样的溶液可以在未使用的镜片表面保留很长时间，从而导致在眼中持续存在的表面修饰，可能在首次使用的新镜片的润湿性能方面提供显着改善，而且甚至在镜片插入后数小时，也能防止干燥并提高润滑性。
• Cationic hydrophilic siloxanyl monomers
  申请人：Schorzman Derek

  公开号：US20070142583A1

  公开（公告）日：2007-06-21

  The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymeric compositions comprise polymerized cationic hydrophilic siloxanyl monomers.

  本发明涉及用于制造生物相容性医疗器械的聚合物组合物。更具体地，本发明涉及某些阳离子单体，其能够聚合形成具有理想物理特性的聚合物组合物，用于制造眼科器械。这些特性包括能够用水提取聚合的医疗器械。这避免了在技术上通常使用的有机溶剂的使用。该聚合物组合物包括聚合的阳离子亲水性硅氧烷单体。
• Preformulated additive for a composition for treating textile fiber articles and use of said additive as care agent
  申请人：——

  公开号：US20030050218A1

  公开（公告）日：2003-03-13

  Preformulated additive for a composition for treating textile fiber articles in aqueous or wet medium, comprising: a particulate solid organic polymer (P) dispersed in and/or encapsulated by a matrix (M) and a surfactant (S) at the matrix (M)/polymer (P) interface, said matrix (M) being soluble or dispersible in said medium and the polymer (P) insoluble and capable of dispersing in said medium in the form of nanoparticles. Use of the preformulated additive as care agent, in particular as crease-resistance agent, in detergent formulations, rinsing/softening formulations, tumble dryer additives and washing additives for textile fiber articles.

  一种预先配制的添加剂，用于在水性或湿性介质中处理纺织品纤维制品，包括：分散在和/或被包覆在基质（M）中的颗粒状固体有机聚合物（P），以及在基质（M）/聚合物（P）界面处的表面活性剂（S），所述基质（M）可在所述介质中溶解或分散，而聚合物（P）不溶且能够以纳米粒子的形式分散在所述介质中。将预先配制的添加剂用作护理剂，特别是用作抗皱剂，在洗涤剂配方、漂洗/柔软剂配方、滚筒烘干机添加剂和纺织品纤维制品洗涤添加剂中。
• CROSSLINKED POLYMER, PROCESS FOR PRODUCING THE SAME, ABSORBENT STRUCTURE, AND ABSORBENT ARTICLE
  申请人：Sanyo Chemical Industries, Ltd.

  公开号：EP1275669A1

  公开（公告）日：2003-01-15

  A crosslinked polymer (A) which comprises, as essential structural units, units derived from (a) one or more vinyl monomers selected from the group consisting of water-soluble vinyl monomers and/or vinyl monomers which become water-soluble upon hydrolysis and units derived from (b) a crosslinking agent and which satisfies the following requirements: (1): (X) ≧ 25g/g, (2): (Y) ≧ 15g/g, and (3): (Y) ≧ -0.54 (X) + 41. It has exceedingly high water retentivity and exceedingly high absorbing power under load. When applied to an absorbent structure and an absorbent article, the polymer has excellent absorbing performance. In the relationships, (X) is the amount of physiological saline retained through 1-hour absorption and (Y) is the amount of physiological saline absorbed through 1-hour standing under a load of 60 g/cm2.

  一种交联聚合物(A)，其基本结构单元包括(a)一种或多种乙烯基单体衍生的单 元，这些乙烯基单体选自由水溶性乙烯基单体和/或水解后变成水溶性的乙烯基单体 组成的组，以及(b)一种交联剂衍生的单元，并满足以下要求：(1):(X) ≧ 25g/g, (2)：(Y) ≧ 15 克/克，及 (3)：(Y) ≧ -0.54 (X) + 41。它具有极高的保水性和极高的负载吸附力。当应用于吸水结构和吸水物品时，该聚合物具有优异的吸水性能。在上述关系中，(X) 是在 60 克/平方厘米的负载下，通过 1 小时的吸收所保留的生理盐水量，(Y) 是在 60 克/平方厘米的负载下，通过 1 小时的静置所吸收的生理盐水量。
• WATER ABSORBING AGENT, PROCESS FOR ITS PRODUCTION, AND ABSORBERS AND ABSORBENT ARTICLES MADE BY USING THE AGENT
  申请人：San-Dia Polymers, Ltd.

  公开号：EP1457541A1

  公开（公告）日：2004-09-15

  A water absorbing agent comprising a crosslinked polymer including a water-soluble vinyl monomer (a1) and/or a vinyl monomer (a2) that is formed into the water-soluble vinyl monomer (a1) by hydrolysis, and a crosslinking agent (b) as an essential constituting unit, wherein the following formulae (1) and (2) are satisfied; a process for its production, and absorbers and absorbent articles made by the water absorbing agent.(Y) ≥ -1.14 (X) + 69.5(X) = ((x1)2 + 4 × (x2)2)1/2 wherein (x1) denotes a water-retention amount (g/g) of the water absorbing agent after being soaked in a physiological saline for one hour; (x2) denotes an absorption amount (g/g) of the water absorbing agent after being soaked in a physiological saline under loading of 0.9 psi for one hour; and (Y) denotes a liquid permeation speed (ml/min) of a physiological saline after the water absorbing agent is soaked in a physiological saline under loading of 0.3 psi for one hour. The water-absorbing agent enables easy production of absorbent articles exhibiting high absorption performance in any state, and is suitable for use in disposable diapers, sanitary napkins, and other sanitary goods.

  一种吸水剂，由交联聚合物组成，交联聚合物包括水溶性乙烯基单体（a1）和/或通过水解形成水溶性乙烯基单体（a1）的乙烯基单体（a2），以及作为基本构成单元的交联剂（b），其中交联剂（b）满足下式（1）和（2）；一种吸水剂的生产工艺，以及由该吸水剂制成的吸水剂和吸水物品。 (Y) ≥ -1.14 (X) + 69.5(X) = ((x1)2 + 4 × (x2)2)1/2 其中，(x1) 表示吸水剂在生理盐水中浸泡一小时后的保水量（克/克）；(x2) 表示吸水剂在生理盐水中以 0.吸水剂在生理盐水中浸泡一小时后的液体渗透速度（毫升/分钟）。这种吸水剂可以轻松生产出在任何状态下都具有高吸水性能的吸水物品，适用于一次性尿布、卫生巾和其他卫生用品。