(meso-tetra(parametoxyphenyl)porphin)Pt | 87695-02-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (meso-tetra(parametoxyphenyl)porphin)Pt
• 英文别名: tetrakis(methoxyphenyl)porphyrinato platinum；PtTMPP
• CAS: 87695-02-1
• 化学式: C₄₈H₃₆N₄O₄Pt
• 分子量: 927.918
• InChiKey: FXMDBQBKTYRANS-NHZJRHMYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  (meso-tetra(parametoxyphenyl)porphin)Pt 在 lithium aluminium tetrahydride 作用下， 反应 32.33h， 生成
  参考文献：
  名称：

  铂（II）环稠合二氢卟酚可作为有效的治疗药物：用于肿瘤成像和光动力疗法治疗的染料。

  摘要：

  描述了铂-二氢卟啉类治疗剂的发现。合成了具有不同亲水度的发光Pt（II）4,5,6,7-四氢吡唑并[1,5- a ]吡啶-二氢卟酚，并研究了它们对人黑素瘤，食道癌和膀胱癌的光毒性。。二（羟甲基）取代的二氢卟酚被确定为探索成像引导光动力疗法的特权分子。除了作为PDT试剂的高活性和本身没有细胞毒性外，该分子还显示了理想的光物理和光化学特性。体内 使用A375黑色素瘤小鼠模型进行的研究证明，该二氢卟酚具有发光探针的非凡特性，并且具有削弱肿瘤生长的能力，从而可以进行图像指导治疗并进行随访。

  DOI：

  10.1016/j.ejmech.2020.112468
• 作为产物：
  描述：

  氢碘酸 、 [tetra(p-methoxyphenyl)porphyrinato]platinum(IV) dibromide 生成 (meso-tetra(parametoxyphenyl)porphin)Pt
  参考文献：
  名称：

  Platinum(IV) tetraphenylporphyrin dibromide complexes: synthesis, characterization, and electrochemistry

  摘要：

  Platinum(IV) porphyrins of the type [Pt-IV(p-X)(4)TPP]Br-2 where (p-X)(4)TPP is a para-substituted tetraphenylporphyrin have been synthesized by direct oxidation of their Pt(II) precursors with Br-2. Both the Pt(II) and Pt(IV) complexes have been characterized by visible and H-1 NMR spectroscopy and their electrochemical properties. In both the oxidation and reduction processes, a substituent effect is evident, and the reduction of Pt-IV-->Pt-II is identified. The oxidation and reduction potentials of the [ Pt-IV(p-X)(4)TPP] Br-2 complexes are compared to those of the [Pt-II(p-X)(4)TPP] precursors and [Pt-IV(p-X)(4)TPP]Cl-2 analogs. Addition of I-2 or I- to Pt(II) porphyrins does not result in oxidative-addition to form Pt(IV) porphyrins. Instead, the addition of I- to [Pt-IV(p-X)(4)TPP]Br-2 results in the reduction of the platinum to form the corresponding [Pt-II(p-X)(4)TPP)]. (C) 2000 Elsevier Science Ltd All rights reserved.

  DOI：

  10.1016/s0277-5387(00)00349-1

文献信息

• The chemical degradation of gas-sensing meso-tetra-arylporphin thin films by high levels of dinitrogen tetroxide
  作者：Colin L. Honeybourne、Callum A.S. Hill

  DOI：10.1016/0022-3697(88)90084-4

  日期：1988.1

  Abstract Thin solid films of free base meso-tetra-arylporphins and their zinc, copper, platinum and palladium complexes have been exposed to high levels of dinitrogen tetroxide (NOX). The optical spectra (300–850 nm) were recorded in transmission before and after exposure to NOX. On the basis of the foregoing spectroscopic evidence, films resistant to permanent chemical damage by high levels of NOX (>

  摘要 游离碱内消旋四芳基卟吩及其锌、铜、铂和钯配合物的固体薄膜已暴露于高浓度的四氧化二氮 (NOX) 中。在暴露于 NOX 之前和之后，光谱（300-850 nm）在透射中记录。根据上述光谱证据，确定了耐高水平 NOX（> 10,000 ppm）造成的永久性化学损伤的薄膜。为那些在被 NOX 化学攻击后可以再生的分子提供了反应方案。强调了这些观察结果与选择适合用作工业气体传感器的固体有机薄膜的相关性。
• Platinum(II) and platinum(IV) porphyrin complexes: synthesis, characterization, and electrochemistry
  作者：L.M. Mink、M.L. Neitzel、L.M. Bellomy、R.E. Falvo、R.K. Boggess、B.T. Trainum、P. Yeaman

  DOI：10.1016/s0277-5387(97)00026-0

  日期：1997.1

  longer wavelengths upon oxidation of the Pt II . All 1 H resonances experience a downfield shift upon oxidation of the Pt II to Pt IV . Each [ Pt II ( p - X ) 4 TPP ] complex shows two oxidations and two reductions and their potentials are dependent upon the X substituent on the porphyrin ring. In general, the [ Pt IV ( p - X ) 4 TPP ] Cl 2 complexes show a similar oxidation and reduction pattern and

  摘要[Pt IV（p-X）4 TPP] Cl 2类型的铂（IV）卟啉是通过将其Pt II前体直接与Cl 2氧化而合成的对位取代的四苯基卟啉。Pt II和Pt IV配合物均已通过可见和1 H NMR光谱及其电化学性质进行了表征。当Pt II氧化时，可见光谱的Soret，α和β谱带移至更长的波长。当Pt II氧化为Pt IV时，所有1 H共振都会发生场下偏移。每个[Pt II（p-X）4 TPP]络合物均显示两次氧化和两次还原，其电势取决于卟啉环上的X取代基。通常，[Pt IV（p-X）4 TPP] Cl 2配合物显示出相似的氧化和还原模式，并且具有明显的取代作用。
• Formylation of metallocomplexes of tetra-meso-(para- and meta-methoxyphenyl)porphyrins
  作者：V. D. Rumyantseva、S. V. Tsukanov、A. F. Mironov

  DOI：10.1134/s1068162007020094

  日期：2007.3

  The Vilsmeier formylation of metallocomplexes of isomeric meta- and para-methoxy-substituted tetraphenylporphyrines has was been studied. Formyl derivatives of meta-isomers were shown to form cyclization products not only in solutions, but also in the the solid state. The ability to undergo such transformations follows decreases in the trend following order: Co > Cu > Ni > Pd > Pt.