2,2,4-三甲戊基磷酸 | 82164-75-8

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 有机磷化合物
• 中文名称: 2,2,4-三甲戊基磷酸
• 中文别名: 一异辛基膦；(2,4,4-三甲基戊基)膦
• 英文名称: mono-2,4,4-trimethylpentylphosphine
• 英文别名: 2,4,4-trimethylpentyl phosphine；2,4,4-trimethylpentylphosphine；Phosphine, (2,4,4-trimethylpentyl)-；2,4,4-trimethylpentylphosphane
• CAS: 82164-75-8
• 化学式: C₈H₁₉P
• 分子量: 146.213
• InChiKey: WKUJXKQEUURINH-UHFFFAOYSA-N

物化性质

• 闪点：
  -17°C

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 危险类别码：
  R14,R17
• 危险品运输编号：
  UN 2845
• 安全说明：
  S16,S43,S45,S7

SDS

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Section 1: Product Identification
Chemical Name: 2,4,4-Trimethylpentylphosphine, 99% (8% isomers)
CAS Registry Number: 82164-75-8
Formula: CH3C(CH3)2CH2CH(CH3)CH2PH2
EINECS Number: none
Chemical Family: organophosphorus ligand
Synonym: None

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Section 2: Composition and Information on Ingredients
Ingredient CAS Number Percent ACGIH (TWA) OSHA (PEL)
Title Compound 82164-75-8 92% no data no data
other isomers not available 8% no data no data

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Section 3: Hazards Identification
Irritating to skin, eyes and respiratory tract. Material has a pungent odor. Inhalation of vapors may lead to
Emergency Overview:
headache and dizziness.
Primary Routes of Exposure: Ingestion, skin, inhalation
Eye Contact: Causes mild to severe irritation of the eyes.
Skin Contact: Irritant. Causes mild irritation of the skin, or thermal burns if ignited.
The material has a pungent odor. Inhalation may lead to headaches and dizziness. Irritating to nose and
Inhalation:
mucous membranes.
Ingestion: May be harmful if swallowed. May cause vomiting and diarrhea.
Acute Health Affects: Irritating to skin, eyes and respiratory tract.
Chronic Health Affects: Overexposure to high concentrations of vapors may lead to systemic abnormalities in the kidneys and lungs.
NTP: No
IARC: No
OSHA: No

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SECTION 4: First Aid Measures
Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need
Eye Exposure:
assistance in keeping their eye lids open. Get immediate medical attention.
Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if
Skin Exposure:
irritation persists.
Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty
Inhalation:
in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance.
Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce
Ingestion:
vomiting only if directed by medical personnel.

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SECTION 5: Fire Fighting Measures
Flash Point: 1°F
Autoignition Temperature: 334°F
Explosion Limits: Pyrophoric
Extinguishing Medium: carbon dioxide, dry powder or foam
The pyrophoric liquid may reignite. Fire fighters should be equipped with an approved positive pressure
Special Fire Fighting Procedures:
self-contained breathing apparatus and full protective clothing.
Hazardous Combustion and If involved in a fire this material may emit toxic organic fumes and vapors of phosphorus pentoxide.
Decomposion Products:
Unusual Fire or Explosion Hazards: Spontaneously flammable in air, especially in contact with organic matter such as paper or cloth.

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SECTION 6: Accidental Release Measures
'The material may ignite spontaneously in air. Avoid static discharge. Burning material may release
toxic fumes. In case of poor ventilation, leave the area unless fitted with a self-contained breathing apparatus.
Spill and Leak Procedures:
Small spills can be mixed with ground limestone, sodium bicarbonate, or other suitable absorbents, swept up,
and held in a closed metal can.

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SECTION 7: Handling and Storage
Store in a tightly sealed container under an inert atmosphere of nitrogen or argon. Keep away from heat.
Handling and Storage: Material should be transferred under an inert atmosphere of nitrogen or argon in a efficient fume hood. Fire
may occur in emptied container and transfer lines.

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SECTION 8: Exposure Controls and Personal Protection
Eye Protection: Always wear approved safety glasses when handling a chemical substance in the laboratory.
Skin Protection: Wear protective clothing and gloves.
Ventilation: Material has a pungent odor. Always handle material in an efficient fume hood.
If ventilation is not available a respirator should be worn. The use of respirators requires a Respirator
Respirator:
Protection Program to be in compliance with 29 CFR 1910.134.
Ventilation: Material has a pungent odor. Always handle material in an efficient fume hood.
Additional Protection: Wear a full face shield, flame resistant lab apron and suitable gloves.

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SECTION 9: Physical and Chemical Properties
Color and Form: colorless liq.
Molecular Weight: 146.21
Melting Point: no data
Boiling Point: no data
Vapor Pressure: no data
Specific Gravity: no data
Odor: phosphine odor
Solubility in Water: insoluble

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SECTION 10: Stability and Reactivity
Stability: air-sensitive liquid - pyrophoric
Hazardous Polymerization: no hazardous polymerization
Contact with air. Material may spontaneously ignite, especially in the presence of organic matter such as
Conditions to Avoid:
paper or cloth.
Incompatibility: oxidizing agents, halogens, air (pyrophoric), halocarbons, sulfur.
Decomposition Products: carbon dioxide, carbon monoxide, organic vapors, and phosphorus pentoxide.

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SECTION 11: Toxicological Information
RTECS Data: No information available in the RTECS files.
Carcinogenic Effects: No data available
Mutagenic Effects: No data available
Tetratogenic Effects: No data available

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SECTION 12: Ecological Information
Ecological Information: No information available

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SECTION 13: Disposal Considerations
Disposal: Dispose of according to local, state and federal regulations.

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SECTION 14: Transportation
Shipping Name (CFR): Pyrophoric liquids, organic, N.O.S.
Hazard Class (CFR): 4.2
Additional Hazard Class (CFR): NA
Packaging Group (CFR): I
UN ID Number (CFR): UN# 2845
Shipping Name (IATA): Forbidden
Hazard Class (IATA): NA
Additional Hazard Class (IATA): NA
Packaging Group (IATA): NA
UN ID Number (IATA): UN# 2845

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SECTION 15: Regulatory Information
TSCA: Listed in the TSCA inventory.
SARA (Title 313): Title compound not listed.
Second Ingredient: none

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  2,2,4-三甲戊基磷酸 在 氢氧化钾 、 肼 作用下， 以 二乙二醇 为溶剂， 生成 1-(2,4,4-trimethyl-pentyl)-2,2,6,6-tetramethyl-phosphorinane
  参考文献：
  名称：

  磷化氢用作钯催化的交叉偶联化学的配体。

  摘要：

  [结构：见正文]磷化氢是一类适用于有机钯交叉偶联化学反应的膦配体。通过将单烷基膦基或芳基膦直接双迈克尔加成到佛酮中，然后进行Wolf-Kishner还原，制备了二膦酸酯，其制造相对便宜，并且允许对烷基部分之一进行修饰，从而可以对配体进行空间和电子微调。介绍了这些配体在Suzuki，Sonogashira，酮芳基化和芳基胺化反应中的文库筛选和应用。

  DOI：

  10.1021/ol052579h

文献信息

• POLYELECTROLYTE POLYMERS, THEIR MANUFACTURE AND USE
  申请人：THE UNIVERSITY OF WESTERN ONTARIO

  公开号：US20160032028A1

  公开（公告）日：2016-02-04

  A method of forming a polyelectrolyte polymer by photopolymerizing a monomer having an ionic group covalently linked to a photocurable group. The ionic group can be borate and/or phosphonium ion. The polymer can be cross-linked as by diacrylate.

  通过光聚合将含有离子基团共价连接到光固化基团的单体形成聚电解质聚合物的方法。离子基团可以是硼酸盐和/或磷酸盐离子。聚合物可以通过双丙烯酸酯进行交联。
• [EN] PHOSPHONIUM IONIC LIQUIDS AND COATINGS MADE THEREFROM<br/>[FR] LIQUIDES IONIQUES À BASE DE PHOSPHONIUM ET REVÊTEMENTS RÉALISÉS À PARTIR DE CEUX-CI
  申请人：UNIV WESTERN ONTARIO

  公开号：WO2009094768A1

  公开（公告）日：2009-08-06

  ABSTRACT The present invention provides phosphonium ionic liquids (11) and coatings made therefrom. Highly fluorinated phosphonium ionic liquids based on (11) having been produced exhibiting high thermal stabilities, low melting points and temperature dependent solvent miscibilities. These salts and derivatives of (11) have also been employed in the preparation of superhydrophobic surfaces, indicating that ionic liquids are not only new alternative solvents, but also viable functional materials. All derivatives of (11) form biphasic systems with common laboratory solvents of ranging polarity at room temperature. Based on the solvent miscibility experiments with water and the high fluorine loading, the PILs showed obvious evidence of being hydrophobic. Coatings made with these phosphonium ionic liquids (11), salts and derivatives thereof were superhydrophobic with water contact angles were measured and all of the surfaces were determined to be superhydrophobic with contact angles > 150°.

  摘要 本发明提供了基于磷酸铵离子液体（11）制备的涂层。已生产出基于（11）的高度氟化磷酸铵离子液体，具有高热稳定性、低熔点和温度相关的溶剂亲和力。这些（11）的盐和衍生物还被用于制备超疏水表面，表明离子液体不仅是新型替代溶剂，也是可行的功能材料。所有（11）的衍生物在室温下与不同极性的常见实验室溶剂形成两相体系。根据与水的溶剂亲和力实验和高氟含量，磷酸铵离子液体显示出明显的疏水性证据。使用这些磷酸铵离子液体（11）、盐和其衍生物制成的涂层都是超疏水的，水接触角度被测量，所有表面被确定为超疏水，接触角大于150°。
• Highly fluorinated phosphonium ionic liquids: novel media for the generation of superhydrophobic coatings
  作者：Jocelyn J. Tindale、Paul J. Ragogna

  DOI：10.1039/b821174d

  日期：——

  A new class of highly fluorinated phosphonium ionic liquids (HFPILs) that are thermally stable, non-volatile, tuneable small molecules has been synthesized; they are uniquely suited for creating novel superhydrophobic coatings, offering a new paradigm in the application of ionic liquids.

  我们合成了一类新的高氟化膦离子液体（HFPILs），它们是热稳定、不挥发、可调节的小分子；它们非常适合用于制造新型超疏水涂层，为离子液体的应用提供了一种新的范例。
• Poly-<i>p</i>-phenylene Phosphine/Polyaniline Alternating Copolymers:  Electronic Delocalization through Phosphorus
  作者：Zhou Jin、Brett L. Lucht

  DOI：10.1021/ja043358u

  日期：2005.4.1

  nitrogen centers show evidence for weak electronic delocalization along the polymer chain. The electrochemical and spectroscopic properties support strong electronic delocalization in copolymers containing -(-P-C(6)H(4)-N-C(6)H(4)-)- repeat units. The presence of a single diphenylphosphine bridge between nitrogen centers provides an efficient mode of electronic delocalization between nitrogen centers

  已制备含磷聚（N-芳基苯胺）和相关聚合物模型化合物。通过紫外-可见-近红外光谱和循环伏安法研究了材料的光谱和电子性质。在聚合物主链中含有对苯二胺单元的 PPPP-PANI 共聚物具有芳香族取代对苯二胺的电子和光谱特性。包含 -(-C(6)H(4)-PC(6)H(4)-PC(6)H(4)-)- 氮中心之间的链接的共聚物显示出沿聚合物链的弱电子离域的证据。电化学和光谱特性支持包含-(-PC(6)H(4)-NC(6)H(4)-)-重复单元的共聚物中的强电子离域。氮中心之间单个二苯基膦桥的存在提供了氮中心之间电子离域的有效模式。还制备和研究了 PPPP 氧化物-PANI 共聚物和相关的聚合物模型化合物。PPPP 氧化物-PANI 共聚物与分离的对苯二胺或三芳基胺的相似之处表明聚合物中胺片段的电子分离。磷 (III) 膦向磷 (V) 氧化膦的转化通过磷抑制电子离域，进一步支持 PPPP-PANI 共
• Strongly adherent surface coatings
  申请人：Wolf Jean-Pierre

  公开号：US20060257681A1

  公开（公告）日：2006-11-16

  In a process for the production of a strongly adherent coating on an inorganic or organic substrate, wherein a), a low-temperature plasma treatment, a corona discharge treatment or a flame treatment is carried out on the inorganic or organic substrate, b) one or more photoinitiators or mixtures of photoinitiators with monomers or/and oligomers, containing at least one ethylenically unsaturated group, or solutions, suspensions or emulsions of the afore-mentioned substances, are applied to the inorganic or organic substrate, and optionally, c) using suitable methods those afore-mentioned substances are dried and/or are irradiated with electromagnetic waves, it proves advantageous to use compounds of formula (I), (II), (III) and/or (IV), IN-L-RG (I), >IN-L-RG 1 -L 1 -H (II), IN-L-RG 1 -L 1 -IN 1 (III), IN-L-RG 1 -L 1 -RG 2 -L 2 -IN 1 (IV), wherein IN and IN 1 are each independently of the others a monacylphosphine, monoacylphosphine oxide or monoacylphosphine sulfide photoinitiator group; L 1 L 1 and L 2 are a single bond or a spacer group; RG is a monovalent radical having at least one ethylenically unsaturated C═C bond; and RG 1 and RG 2 are each independently of the other a divalent radical having at least one ethylenically unsaturated C═C bond.

  在一种生产无机或有机基材上强附着涂层的过程中，其中a）在无机或有机基材上进行低温等离子处理、电晕放电处理或火焰处理；b）将一个或多个光引发剂或光引发剂与至少一个乙烯基不饱和基团的单体或/和低聚物混合物，或上述物质的溶液、悬浮液或乳液应用于无机或有机基材上，并且可选地，c）使用适当的方法干燥上述物质和/或用电磁波照射，使用式（I）、（II）、（III）和/或（IV）的化合物是有利的，IN-L-RG（I）、>IN-L-RG1-L1-H（II）、IN-L-RG1-L1-IN1（III）、IN-L-RG1-L1-RG2-L2-IN1（IV），其中IN和IN1分别独立地是单酰基膦、单酰基膦氧化物或单酰基膦硫化物光引发剂基团；L1和L2是单键或空间基团；RG是具有至少一个乙烯基不饱和C = C键的一价基团；RG1和RG2分别独立地是具有至少一个乙烯基不饱和C = C键的二价基团。