N,N'-diamino-guanidine; nitrate | 10308-83-5

• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机含氧阴离子化合物
• 英文名称: N,N'-diamino-guanidine; nitrate
• 英文别名: N,N'-Diamino-guanidin; Nitrat；N,N'-Diamino-guanidinium-nitrat；1,3-diaminoguanidine nitrate；1,2-Diaminoguanidine;nitric acid；1,2-diaminoguanidine;nitric acid
• CAS: 10308-83-5
• 化学式: CH₇N₅*HNO₃
• 分子量: 152.113
• InChiKey: BVGPZRCQJJMXBI-UHFFFAOYSA-N

物化性质

• 沸点：
  274.55°C (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.71
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  169
• 氢给体数：
  5
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  N,N'-diamino-guanidine; nitrate 在 水 、 溶剂黄146 、 sodium nitrite 作用下， 生成 5-叠氮基-2H-四唑
  参考文献：
  名称：

  The Reaction of Nitrous Acid with Diaminoguanidine in Acetic Acid Media. Isolation and Structure Proof of Reaction Products¹

  摘要：

  DOI：

  10.1021/ja01147a135
• 作为产物：
  描述：

  1,3-二氨基胍盐酸盐 、 alkaline earth salt of/the/ methylsulfuric acid 在 Amberlite IRA-400 (OH^- - form) 作用下， 生成 N,N'-diamino-guanidine; nitrate
  参考文献：
  名称：

  Shape selection in the association of diaminoguanidinium cation with counterions

  摘要：

  DOI：

  10.1021/jo00294a008

文献信息

• Substituted aminobenzylideneamino guanidine compounds
  申请人：American Cyanamid Company

  公开号：US03941825A1

  公开（公告）日：1976-03-02

  The preparation of 1-amino-3-(4- and 3,4-substituted benzylideneamino)guanidine and the acid addition salts thereof, and their use as intermediates in the preparation of 1,3-bis(4- and 3,4-substituted benzylideneamino)guanidines and their acid addition salts. The final compounds prepared from the present intermediates have antiprotozoal activity particularly against coccidiosis and malaria.

  制备1-氨基-3-(4-和3,4-取代苯基亚胺)胍和其酸加盐，以及它们作为1,3-双(4-和3,4-取代苯基亚胺)胍和其酸加盐制备中间体的用途。从目前的中间体制备的最终化合物具有抗原虫活性，特别针对球虫病和疟疾。
• Substituted aminochlorobenzylamino guanidine compounds
  申请人：American Cyanamid Company

  公开号：US03992446A1

  公开（公告）日：1976-11-16

  The preparation of 1-amino-3-(4- and 3,4-substituted benzylideneamino)guanidine and the acid addition salts thereof, and their use as intermediates in the preparation of 1,3-bis-(4- and 3,4-substituted benzylideneamino)guanidines and their acid addition salts. The final compounds prepared from the present intermediates have antiprotozoal activity particularly against coccidiosis and malaria.

  1-氨基-3-(4-和3,4-取代苄亚胺基)脲及其酸加成盐的制备，以及它们作为1,3-双(4-和3,4-取代苄亚胺基)脲及其酸加成盐的中间体的用途。从当前中间体制备的最终化合物具有抗原虫活性，特别是对球虫病和疟疾。
• Method of producing triaminoguanidine nitrate
  申请人：The United States of America as represented by the Secretary of the Navy

  公开号：US05041661A1

  公开（公告）日：1991-08-20

  A process for preparing triaminoguanidine nitrate from relatively impure -99 percent)/commercial guanidine nitrate and commercial grade aqueous hydrazine (50-64 weight percent) in alcohol by: (1) adding enough hydrazine to form monoaminoguanidine nitrate, diaminoguanidine nitrate, or mixtures thereof, (2) physically removing the alcohol insoluble, solid impurities from the solution, (3) adding the remainder of the hydrazine needed to form triaminoguanidine nitrate, (4) adding nitric acid to adjust the pH to from 4.5 to 5.5, and (6) isolating the product triaminoguanidine nitrate.

  从相对不纯（99％）/商业级硝酸胍和50-64重量％的商业级水合肼（50-64重量％）的酒精中制备三胍硝酸盐的过程为：（1）添加足够的水合肼形成一胍硝酸盐，二胍硝酸盐或其混合物，（2）从溶液中物理去除不溶于酒精的固体杂质，（3）添加剩余所需的水合肼以形成三胍硝酸盐，（4）加入硝酸以调节pH值为4.5至5.5，（6）分离产物三胍硝酸盐。
• Polynitrogen Systems from Hydrazinocarbonic Acids. I. Diformazans¹
  作者：F. L. Scott、D. A. O'Sullivan、J. Reilly

  DOI：10.1021/ja01117a049

  日期：1953.11
• Gaiter, Gazzetta Chimica Italiana, 1915, vol. 45 I, p. 457
  作者：Gaiter

  DOI：——

  日期：——