3,4,5-trihydroxy-6-methyltetrahydropyran-2-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,4,5-trihydroxy-6-methyltetrahydropyran-2-one
• 英文别名: 3,4,5-Trihydroxy-6-methyloxan-2-one
• 化学式: C₆H₁₀O₅
• 分子量: 162.142
• InChiKey: ZVAHHEYPLKVJSO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.5
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3,4,5-trihydroxy-6-methyltetrahydropyran-2-one 在 磷酸 作用下， 反应 0.75h， 生成 3-羟基-6-甲基吡喃-2-酮
  参考文献：
  名称：

  Identification of Potent Aroma Compounds in Thermally Treated Mixtures of Glucose/Cysteine and Rhamnose/Cysteine Using Aroma Extract Dilution Techniques

  摘要：

  Application of an aroma extract dilution analysis on extracts prepared from either thermally treated solutions (20 min, 145 degrees C) of glucose/cysteine (I) or rhamnose/cysteine (II) led to the identification of 2-furfurylthiol (roasty, coffee-like), 5-acetyl-2,3-dihydro-1,4-thiazine (roasty), 3-mercapto-2-butanone (sulfury, rotten), 3-mercapto-2-pentanone (catty), and 4-hydroxy-2,5-dimethyl-3(2H)-furanone (caramel-like) with the highest odor activities among the 34 odor-active volatiles detected in I. In II, 4-hydroxy-2,5-dimethyl-3(2H)-furanone, 3-hydroxy-6-methyl-2(2H)-pyranone (seasoning-like), 5-methyl-2-furfurylthiol (roasty, coffee-like), 2-furfurylthiol, and 5-acetyl-2,3-dihydro-1,4-thiazine appeared with the highest flavor dilution (FD) factors among the 18 compounds detected by HRGC/O. Among the flavor compounds identified, 2-propionyl-2-thiazoline is reported for the first time among the flavors of Maillard model reactions or foods, respectively. The odorant elicited an intense roasty, popcorn-like odor at the low odor threshold of 0.07 ng/L in air.

  DOI：

  10.1021/jf960456t
• 作为产物：
  描述：

  L-rhamnopyranose 在 溴 、 barium benzoate 作用下， 以 水 为溶剂， 反应 36.0h， 生成 3,4,5-trihydroxy-6-methyltetrahydropyran-2-one
  参考文献：
  名称：

  Identification of Potent Aroma Compounds in Thermally Treated Mixtures of Glucose/Cysteine and Rhamnose/Cysteine Using Aroma Extract Dilution Techniques

  摘要：

  Application of an aroma extract dilution analysis on extracts prepared from either thermally treated solutions (20 min, 145 degrees C) of glucose/cysteine (I) or rhamnose/cysteine (II) led to the identification of 2-furfurylthiol (roasty, coffee-like), 5-acetyl-2,3-dihydro-1,4-thiazine (roasty), 3-mercapto-2-butanone (sulfury, rotten), 3-mercapto-2-pentanone (catty), and 4-hydroxy-2,5-dimethyl-3(2H)-furanone (caramel-like) with the highest odor activities among the 34 odor-active volatiles detected in I. In II, 4-hydroxy-2,5-dimethyl-3(2H)-furanone, 3-hydroxy-6-methyl-2(2H)-pyranone (seasoning-like), 5-methyl-2-furfurylthiol (roasty, coffee-like), 2-furfurylthiol, and 5-acetyl-2,3-dihydro-1,4-thiazine appeared with the highest flavor dilution (FD) factors among the 18 compounds detected by HRGC/O. Among the flavor compounds identified, 2-propionyl-2-thiazoline is reported for the first time among the flavors of Maillard model reactions or foods, respectively. The odorant elicited an intense roasty, popcorn-like odor at the low odor threshold of 0.07 ng/L in air.

  DOI：

  10.1021/jf960456t

文献信息

• ANALYTE SENSORS AND METHODS FOR MAKING AND USING THEM
  申请人：Medtronic MiniMed, Inc.

  公开号：EP1751302B1

  公开（公告）日：2012-03-28
• Analyte sensors and methods for making and using them
  申请人：Wang Yunbing

  公开号：US20080026473A1

  公开（公告）日：2008-01-31

  Embodiments of the invention provide analyte sensors having elements designed to modulate their chemical reactions as well as methods for making and using such sensors. In certain embodiments of the invention, the sensor includes a hydrophilic comb-copolymer having a central chain and a plurality of side chains coupled to the central chain, wherein at least one side chain comprises a silicone moiety.
• Ascorbic Acid - Natural Sugar Lactone Esters for Comprehensive Skin & Scalp Care
  申请人：GUPTA SHYAM K.

  公开号：US20080287533A1

  公开（公告）日：2008-11-20

  This invention relates to esters of ascorbic acid with natural sugar lactones [formula (I)], which are useful for the treatment of skin condition, including age spots, acne, loss of cellular antioxidants, collagen loss, loss of skin pliability, loss of skin suppleness, skin wrinkles including fine lines, oxidation, damage from radiation, malfunction of matrix metalloproteases, malfunction of tyrosinases, damage from free radicals, damage from UV, dry skin, xerosis, ichthyosis, dandruff, brownish spots, keratoses, melasma, lentigines, liver spots, pigmented spots, dark circles under the eyes, skin pigmentation including darkened skin, blemishes, oily skin, warts, eczema, pruritic skin, psoriasis, inflammatory dermatoses, topical inflammation, disturbed keratinization, skin changes associated with aging, nail or skin requiring cleansers, conditioning or treatment, and hair or scalp requiring shampooing or conditioning, and combinations thereof;
• ANALYTE SENSOR APPARATUSES COMPRISING MULTIPLE IMPLANTABLE SENSOR ELEMENTS AND METHODS FOR MAKING AND USING THEM
  申请人：Gottlieb Rebecca K.

  公开号：US20100030045A1

  公开（公告）日：2010-02-04

  Embodiments of the invention provide analyte sensors having optimized elements and/or configurations of elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.
• US7842723B2
  申请人：——

  公开号：US7842723B2

  公开（公告）日：2010-11-30