4-oxo-2,4-diphenyl-cis-crotonic acid | 879406-81-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 4-oxo-2,4-diphenyl-cis-crotonic acid
• 英文别名: 4-Oxo-2,4-diphenyl-cis-crotonsaeure；(Z)-4-oxo-2,4-diphenylbut-2-enoic acid
• CAS: 879406-81-2
• 化学式: C₁₆H₁₂O₃
• 分子量: 252.269
• InChiKey: MHEWHQYEOQYLQL-KAMYIIQDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  氯仿 、 4-oxo-2,4-diphenyl-cis-crotonic acid 生成 苯甲酰甲酸
  参考文献：
  名称：

  Kohler, Goodwin, Journal of the American Chemical Society, 1927, vol. 49, p. 222

  摘要：

  DOI：
• 作为产物：
  描述：

  3-hydroxy-4-oxo-2,4-diphenyl-butyric acid 在 盐酸 、 氢氧化钾 、 sodium hydroxide 、 盐酸羟胺 作用下， 生成 4-oxo-2,4-diphenyl-cis-crotonic acid
  参考文献：
  名称：

  Kohler, Goodwin, Journal of the American Chemical Society, 1927, vol. 49, p. 222

  摘要：

  DOI：

文献信息

• Polymer material, composition, and method of manufacturing semiconductor device
  申请人：TOSHIBA MEMORY CORPORATION

  公开号：US11192972B2

  公开（公告）日：2021-12-07

  According to one embodiment, a polymer material is disclosed. The polymer material contains a polymer. The polymer contains a first monomer unit having a lone pair and an aromatic ring at a side chain, and a second monomer unit including a crosslinking group at a terminal of the side chain, with its molar ratio of 0.5 mol % to 10 mol % to all monomer units in the polymer. The polymer material can be used for manufacturing a composite film as a mask pattern for processing a target film on a substrate. The composite film can be formed by a process including, forming an organic film on the target film with the polymer material, patterning the organic film, and forming the composite film by impregnating a metal compound into the patterned organic film.

  根据一个实施方案，公开了一种聚合物材料。该聚合物材料包含一种聚合物。该聚合物包含第一单体单元和第二单体单元，第一单体单元在侧链上具有孤对和芳香环，第二单体单元在侧链的末端包括交联基团，其与聚合物中所有单体单元的摩尔比为 0.5 摩尔%至 10 摩尔%。该聚合物材料可用于制造复合薄膜，作为在基底上加工目标薄膜的掩模图案。复合薄膜的形成过程包括：用聚合物材料在目标薄膜上形成有机薄膜，对有机薄膜进行图案化，以及通过将金属化合物浸渍到图案化的有机薄膜中形成复合薄膜。
• The Reactions of Certain Gamma Ketonic Acids. I. Ketonic Beta Lactones
  作者：E. P. Kohler、R. H. Kimball

  DOI：10.1021/ja01318a061

  日期：1934.3
• Point of care and central laboratory determinations of the aPTT are not interchangeable in surgical intensive care patients
  作者：Martine Ferring、Guido Reber、Philippe de Moerloose、Paolo Merlani、Marc Diby、Bara Ricou

  DOI：10.1007/bf03020384

  日期：2001.12

  Purpose: The objective of the study was to compare a bedside whole blood activated partial thromboplastin time (aPTT) performed by a point of care (POC) apparatus (CoaguCheck (R) Pro) in surgical intensive care (SIC) patients with a conventional aFTT obtained from the central laboratory.Methods: The prospective concomitant measurements of the two aPTT were performed in 233 samples from 46 consecutive patients admitted after cardiovascular or major abdominal surgery.Results: Inter-operator, inter-instrument and inter-cartridge variability of the new device measured in three healthy volunteers and in nine patients in stable condition (controls) was low (F test: P=0.86). The agreement by Bland and Altman between POC and central laboratory aPTT (-20.2 +/- 18.8 sec) was not satisfactory. The agreement between POC and central laboratory aPTT in patients after surgery was worst (-17 +/- 33.1 sec). Heparin treatment or timing of blood sampling after intensive care admission (< 48 hr Ys > 48 hr) did not influence the agreement. The correlation between POC or central laboratory aPTT and anti-factor Xa activity was poor (r(2) 0.077 and 0.181 respectively). The test which correlated the best to heparin doses was anti-factor Xa activity (r(2) 0.714),Conclusion: POC aPTT and central laboratory aPTT showed a poor agreement in SIC patients admitted after surgery, although in healthy volunteers or in control patients, this agreement was better. The best test to monitor heparin treatment in this setting was anti-factor Xa activity.
• POLYMER MATERIAL, COMPOSITION, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE
  申请人：TOSHIBA MEMORY CORPORATION

  公开号：US20200291156A1

  公开（公告）日：2020-09-17

  According to one embodiment, a polymer material is disclosed. The polymer material contains a polymer. The polymer contains a first monomer unit having a lone pair and an aromatic ring at a side chain, and a second monomer unit including a crosslinking group at a terminal of the side chain, with its molar ratio of 0.5 mol % to 10 mol % to all monomer units in the polymer. The polymer material can be used for manufacturing a composite film as a mask pattern for processing a target film on a substrate. The composite film can be formed by a process including, forming an organic film on the target film with the polymer material, patterning the organic film, and forming the composite film by impregnating a metal compound into the patterned organic film.
• [EN] POLYMERIZATION INHIBITOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE<br/>[FR] COMPOSITIONS INHIBITRICES DE POLYMÉRISATION, LEUR PRÉPARATION ET LEUR UTILISATION
  申请人：ALBEMARLE CORP

  公开号：WO2008060844A1

  公开（公告）日：2008-05-22

  [EN] This invention provides a liquid polymerization inhibitor composition formed from ingredients comprised of tris(N-nitroso-N-phenylhydroxylamine)aluminum salt and a) 2-hydroxy-2-methylpropiophenone, 2-hydroxy-4'-(2-hydroxyethoxy)-2- methylpropiophenone, a,a-diethoxyacetophenone, or 1-benzoylcyclohexanol, or a combination of any two or more of these; or b) benzophenone, at least one ester having a benzoylphenyl group therein, or at least one acrylate having a benzoylphenyl group therein, or a combination of any two or more of these; or c) both a) and b). When a) is 1-benzoylcyclohexanol, then at least one ingredient from b) is also present in said composition.
  [FR] L'invention concerne une composition liquide inhibitrice de polymérisation formée à partir d'ingrédients composés d'un sel d'aluminium tris(N-nitroso-N-phenylhydroxylamine) et a) de 2-hydroxy-2-methylpropiophenone, 2-hydroxy-4'-(2-hydroxyethoxy)-2- methylpropiophenone, a,a-diethoxyacetophenone, ou de 1-benzoylcyclohexanol, ou d'une combinaison de deux composés quelconques ou plus; ou b) d'un benzophénone, d'au moins un ester comprenant un groupe benzoylphényle, ou d'au moins un acrylate comprenant un groupe benzoylphényle, ou d'une combinaison de deux composés quelconques ou plus; ou c) à la fois de a) et de b). Lorsque a) est 1-benzoylcyclohexanol, au moins un ingrédient provenant de b) est également présent dans la composition.