3,4,5-三氯吡啶-2-甲腈 | 139485-42-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 3,4,5-三氯吡啶-2-甲腈
• 英文名称: 3,4,5-trichloro-2-picolinonitrile
• 英文别名: 3,4,5-trichloropyridine-2-carbonitrile；3,4,5-Trichloropicolinonitrile
• CAS: 139485-42-0
• 化学式: C₆HCl₃N₂
• mdl: MFCD00160333
• 分子量: 207.446
• InChiKey: UBUTVAIAQCVVBX-UHFFFAOYSA-N

物化性质

• 沸点：
  281.9±35.0 °C(Predicted)
• 密度：
  1.63±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  36.7
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2933399090

反应信息

• 作为反应物：
  描述：

  2,2,2-三氟乙醇 、 3,4,5-三氯吡啶-2-甲腈 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 20.17h， 生成 3,5-dichloro-4-(2,2,2-trifluoroethoxy)pyridine-2-carbonitrile
  参考文献：
  名称：

  [EN] PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST
  [FR] COMPOSÉ DE PYRIDINE, COMPOSITION PESTICIDE ET PROCÉDÉ DE LUTTE CONTRE LES NUISIBLES

  摘要：

  以下是通用公式（1）表示的吡啶化合物；其中R1是C1-C3氟烷基或C1-C3氟烷氧基的吡啶化合物；其中R2是氢原子的吡啶化合物；其中R2是由Q1表示的基团的吡啶化合物；包含所述吡啶化合物作为活性成分的杀虫剂组合物；以及一种控制害虫的方法，包括向害虫或害虫栖息地施加有效量的吡啶化合物。

  公开号：

  WO2009066786A1
• 作为产物：
  描述：

  2-氰基吡啶 在 氯 作用下， 以 四氯化碳 为溶剂， 以75.4%的产率得到3,4,5,6-四氯吡啶氰
  参考文献：
  名称：

  Ovchinnikov, V. G.; Matyusha, A. G.; Litvinenko, G. S., Journal of applied chemistry of the USSR, 1991, vol. 64, # 6.2, p. 1155 - 1159

  摘要：

  DOI：

文献信息

• PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS
  申请人：Dow AgroSciences LLC

  公开号：US20170247330A1

  公开（公告）日：2017-08-31

  4-Alkoxy-3-hydroxypicolinic acids may be conveniently prepared from 2-hydroxypicolinonitrile in a series of chemical steps selected from chlorination, chloro substitution, nitrile hydrolysis and chloro reduction.

  4-烷氧基-3-羟基吡啶甲酸可以通过从2-羟基吡啶甲腈经过一系列化学步骤制备而得，这些步骤包括氯化、氯代取代、腈水解和氯还原。
• Pyridine compound, pesticidal composition and method of controlling pests
  申请人：Sumitomo Chemical Company, Limited

  公开号：US08318776B2

  公开（公告）日：2012-11-27

  A pyridine compound represented by the following general formula (1); the pyridine compound in which R1 is a C1-C3 fluoroalkyl group or a C1-C3 fluoroalkoxy group; the pyridine compound in which R2 is a hydrogen atom; the pyridine compound in which R2 is a group represented by Q1; a pesticidal composition containing the pyridine compound as an active ingredient; and a method of controlling a pest including applying an effective amount of the pyridine compound to the pest or a place where the pest inhabits, are provided.

  提供以下一般式（1）所表示的吡啶化合物；其中R1为C1-C3氟烷基或C1-C3氟烷氧基的吡啶化合物；其中R2为氢原子的吡啶化合物；其中R2为Q1所表示的基团的吡啶化合物；包含上述吡啶化合物作为活性成分的杀虫组合物；以及控制害虫的方法，包括将有效量的吡啶化合物应用于害虫或害虫栖息的地方。
• PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST
  申请人：Mizuno Hajime

  公开号：US20100286148A1

  公开（公告）日：2010-11-11

  A pyridine compound represented by the following general formula (1); the pyridine compound in which R 1 is a C1-C3 fluoroalkyl group or a C1-C3 fluoroalkoxy group; the pyridine compound in which R 2 is a hydrogen atom; the pyridine compound in which R 2 is a group represented by Q; a pesticidal composition containing the pyridine compound as an active ingredient; and a method of controlling a pest including applying an effective amount of the pyridine compound to the pest or a place where the pest inhabits, are provided.

  提供以下通式（1）所表示的吡啶化合物；其中R1为C1-C3氟烷基或C1-C3氟烷氧基的吡啶化合物；其中R2为氢原子的吡啶化合物；其中R2为由Q表示的基团的吡啶化合物；包含该吡啶化合物作为活性成分的杀虫组合物；以及一种控制害虫的方法，包括将有效量的该吡啶化合物应用于害虫或害虫栖息的地方。
• Method for production of nuclear halogenated aromatic compound possessing cyano groups
  申请人：NIPPON SHOKUBAI CO., LTD.

  公开号：EP0795541A1

  公开（公告）日：1997-09-17

  A nuclear halogenated aromatic compound possessing cyano groups is produced by a method using as a raw material an aromatic compound which possesses cyano groups and assumes a solid state at room temperature and subjecting the raw material to a procedure comprising a step of melting and transporting the compound by a means transport-melting, a step of vaporizing the compound, a step of mixing the compound with a halogen gas, and a step of causing the vapor of the compound to react with the halogen gas in vapor phase in the presence of a catalyst sequentially in the order mentioned, which comprises maintaining a content of a self-condensate of the aromatic compound possessing cyano groups which arise during the melting of the aromatic compound possessing cyano groups in a gas of the compound which reacts with the halogen gas to a level of not more than 2.5 mol% based on the compound. The catalyst used in the method is activated carbon such that the average pore radius thereof determined by the nitrogen adsorption method is not less than 12.2 Å and the cumulative pore volume of the portion of the activated carbon having pore radiuses in the range of 5 - 100 Å determined by the steam adsorption method is not less than 0.45 g/cc.

  一种具有氰基的核卤化芳香族化合物的制备方法是，以一种具有氰基并在室温下呈固态的芳香族化合物为原料，将该原料置于一个程序中，该程序包括用一种运输-熔化方法熔化和运输该化合物的步骤、使该化合物气化的步骤、使该化合物与卤素气体混合的步骤，以及使该化合物的蒸气在有催化剂存在的情况下按上述顺序与气相中的卤素气体反应的步骤、在催化剂存在下，使化合物蒸气在气相中与卤素气体按上述顺序依次反应的步骤，该步骤包括将与卤素气体反应的化合物气体中具有氰基的芳香族化合物在熔化过程中产生的具有氰基的芳香族化合物自缩合物的含量保持在不超过化合物总量的 2.5 mol%。本发明方法中使用的催化剂是活性炭，其平均孔半径用氮吸附法测定不小于 12.2 Å，孔半径在 5 - 100 Å范围内的活性炭部分的累积孔体积用蒸汽吸附法测定不小于 0.45 g/cc。
• PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES
  申请人：Dow AgroSciences LLC

  公开号：EP2668163A2

  公开（公告）日：2013-12-04