2-Bromo-1-(4-pentylphenyl)propan-1-one | 488702-76-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Bromo-1-(4-pentylphenyl)propan-1-one
• CAS: 488702-76-7
• 化学式: C₁₄H₁₉BrO
• 分子量: 283.208
• InChiKey: QYYPJIAUMORNOZ-UHFFFAOYSA-N

物化性质

• 沸点：
  345.3±25.0 °C(Predicted)
• 密度：
  1.213±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-Bromo-1-(4-pentylphenyl)propan-1-one 、 2,2,2-三氟乙酰胺 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 生成 2,2,2-trifluoro-N-(1-oxo-1-(4-pentylphenyl)propan-2-yl)acetamide
  参考文献：
  名称：

  5-Aryl-imidazolin-2-ones as a scaffold for potent antioxidant and memory-improving activity

  摘要：

  A series of 5-phenyl-substituted-N-alkyl-imidazolin-2-ones with potent radical-scavenging activity and lipid peroxidation inhibitory activity was synthesized. Many of the compounds showed memory-improving effect in animal models independent of the inhibitory activity on lipid peroxidation. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2007.12.064
• 作为产物：
  描述：

  1-(4-戊基苯基)-1-丙酮 在 溴 作用下， 生成 2-Bromo-1-(4-pentylphenyl)propan-1-one
  参考文献：
  名称：

  5-Aryl-imidazolin-2-ones as a scaffold for potent antioxidant and memory-improving activity

  摘要：

  A series of 5-phenyl-substituted-N-alkyl-imidazolin-2-ones with potent radical-scavenging activity and lipid peroxidation inhibitory activity was synthesized. Many of the compounds showed memory-improving effect in animal models independent of the inhibitory activity on lipid peroxidation. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2007.12.064

文献信息

• US6509367B1
  申请人：——

  公开号：US6509367B1

  公开（公告）日：2003-01-21
• 5-Aryl-imidazolin-2-ones as a scaffold for potent antioxidant and memory-improving activity
  作者：Kazutoshi Watanabe、Yasuhiro Morinaka、Yoshio Hayashi、Masaki Shinoda、Hiroyoshi Nishi、Nobuko Fukushima、Toshiaki Watanabe、Akira Ishibashi、Satoshi Yuki、Masahiko Tanaka

  DOI：10.1016/j.bmcl.2007.12.064

  日期：2008.2

  A series of 5-phenyl-substituted-N-alkyl-imidazolin-2-ones with potent radical-scavenging activity and lipid peroxidation inhibitory activity was synthesized. Many of the compounds showed memory-improving effect in animal models independent of the inhibitory activity on lipid peroxidation. (c) 2008 Elsevier Ltd. All rights reserved.