2,3,4,5-Tetra-O-trimethylsilylxylose | 18623-22-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3,4,5-Tetra-O-trimethylsilylxylose
• 英文别名: Trimethylsilyl-D-plus-xylose；(2R,3S,4R)-2,3,4,5-tetrakis(trimethylsilyloxy)pentanal
• CAS: 18623-22-8
• 化学式: C₁₇H₄₂O₅Si₄
• 分子量: 438.859
• InChiKey: DWTGGLMCGFIELV-GVDBMIGSSA-N

物化性质

• 沸点：
  355.1±42.0 °C(Predicted)
• 密度：
  0.921±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  26
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  54
• 氢给体数：
  0
• 氢受体数：
  5

安全信息

• 海关编码：
  2931900090

反应信息

• 作为产物：
  描述：

  1-O-3,4-(dihydroxyphenyl)ethyl-β-D-apiofuranosyl-(1->2)-β-D-xylopyranosyl-(1->3)-4-O-caffeoyl-β-D-glucopyranoside 、 三甲基硅咪唑 在 盐酸 、 水 、 吡啶 作用下， 反应 4.08h， 生成 、 2,3,4,5-Tetra-O-trimethylsilylxylose 、 2,3,4,5,6-pentakis-O-(trimethylsilyl)-D-glucose
  参考文献：
  名称：

  Phenylethanoid Glycosides from Lantana fucata with in Vitro Anti-inflammatory Activity

  摘要：

  A phytochemical analysis of Lantana fucata dried leaves led to the isolation of three new phenylethanoid glycosides, fucatosides A-C, along with parvifloroside A and six known methoxyflavones. Their structures were established by NMR and ESIMS experiments. In vitro assays showed that the alcoholic extract and fucatoside C have significant anti-inflammatory effects, inhibiting NO release in the LPS-induced J774.Al murine macrophage cell line.

  DOI：

  10.1021/np9002383

文献信息

• Triterpenoid saponins from<i>Gynostemma pentaphyllum</i>
  作者：Lin Shi、Jia-Qing Cao、Sheng-Ming Shi、Yu-Qing Zhao

  DOI：10.1080/10286020.2010.547029

  日期：2011.2

  Four new dammarane-type triterpene saponins, 1–4, were isolated from the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino. Their structural elucidations were accomplished mainly on the basis of spectroscopic methods, such as IR, HR-TOF-MS, and NMR. Compounds 1–4 showed moderate cytotoxic activities against cancer cell lines HL-60, Colon205, and Du145 in vitro.

  四个新达玛烷型三萜皂甙，1 - 4，从地上部分分离绞股蓝（藤）牧野。它们的结构阐明主要是基于光谱方法，例如IR，HR-TOF-MS和NMR。化合物1 - 4显示针对癌细胞系HL-60，Colon205和DU145中度细胞毒活性在体外。