1-(3-(chloromethyl)phenyl)-2-hydroxy-2-methylpropan-1-one | 1308332-52-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(3-(chloromethyl)phenyl)-2-hydroxy-2-methylpropan-1-one
• 英文别名: 2-Hydroxy-1-[3-(hydroxymethyl)phenyl]-2-methyl-1-propanone；2-hydroxy-1-[3-(hydroxymethyl)phenyl]-2-methylpropan-1-one
• CAS: 1308332-52-6
• 化学式: C₁₁H₁₄O₃
• 分子量: 194.23
• InChiKey: UZFYJOPHCKOAKF-UHFFFAOYSA-N

物化性质

• 沸点：
  361.9±27.0 °C(Predicted)
• 密度：
  1.174±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-(3-(chloromethyl)phenyl)-2-hydroxy-2-methylpropan-1-one 在 氯化亚砜 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以92%的产率得到Bis[[3-(2-hydroxy-2-methylpropanoyl)phenyl]methyl] sulfite
  参考文献：
  名称：

  Para—or meso-functionalized aromatic ketone compounds, preparation methods thereof, and photopolymerization initiators comprising the same

  摘要：

  本发明公开了新颖的芳香酮化合物，其在对位或间位具有功能性取代基，可用作乙烯基不饱和体系光聚合的光引发剂或光引发剂混合物的有效成分。这些化合物的制备方法也一并公开。

  公开号：

  US08742175B2
• 作为产物：
  描述：

  2-羟基-2-甲基-1-苯基-1-丙酮 在 aluminum (III) chloride 、 lithium hydroxide 作用下， 以 氯仿 为溶剂， 反应 12.0h， 生成 1-(3-(chloromethyl)phenyl)-2-hydroxy-2-methylpropan-1-one
  参考文献：
  名称：

  Para—or meso-functionalized aromatic ketone compounds, preparation methods thereof, and photopolymerization initiators comprising the same

  摘要：

  本发明公开了新颖的芳香酮化合物，其在对位或间位具有功能性取代基，可用作乙烯基不饱和体系光聚合的光引发剂或光引发剂混合物的有效成分。这些化合物的制备方法也一并公开。

  公开号：

  US08742175B2

文献信息

• [EN] HYBRID PHOTOINITIATORS<br/>[FR] PHOTOINITIATEURS HYBRIDES
  申请人：BASF SE

  公开号：WO2014060450A1

  公开（公告）日：2014-04-24

  Compounds of the formula (I), wherein m is 1 or 2; R1, R2, R4 and R5 independently of one another are hydrogen, C1-C4alkyl, C5-C7 cyclo-alkyl, phenyl, C1-C4alkoxy, C5-C7cycloalkoxy or phenoxy; R3, if m is 1, has one of the meanings as given above for R1, R2, R4 and R5; R3, if m is 2, is a divalent group; R6 is hydrogen or C1-C4alkyl; R7 is hydrogen, and if R6 is hydrogen then R7 may additionally be C1-C4alkyl; R8 is group (A) or (B) X is O, O-CH2- or -O(CHR14)-; n is 0-10; provided that(i) if n is 0, and X is O, then R8 is a group A; (ii) if n is other than 0, then X is O and R8 is the group A; R9 and R10 independently of one another are hydrogen or C1-C4alkyl; R11 and R12 independently of one another are C1-C4alkyl or form together with the C atom to which they are attached a 5 to 7 membered saturated carbocyclic ring; R13 is hydrogen, C1-C4alkyl, C5-C7cycloalkyl, 2-tetrahydropyranyl or Si(C1-C4alkyl)3; R14 is a group (A'); and R'13 has one of the meanings as given for R13 or is the group (C); are effective photoinitiator compounds.

  式(I)的化合物，其中m为1或2；R1、R2、R4和R5分别独立地为氢、C1-C4烷基、C5-C7环烷基、苯基、C1-C4烷氧基、C5-C7环烷氧基或苯氧基；若m为1，则R3具有上述给定的R1、R2、R4和R5中的一种含义；若m为2，则R3为二价基团；R6为氢或C1-C4烷基；R7为氢，若R6为氢，则R7还可以是C1-C4烷基；R8为(A)或(B)基团，X为O、O-CH2-或-O(CHR14)-；n为0-10；条件是(i)若n为0，且X为O，则R8为A基团；(ii)若n不为0，则X为O且R8为A基团；R9和R10分别独立地为氢或C1-C4烷基；R11和R12分别独立地为C1-C4烷基，或与它们所连接的碳原子形成一个5到7元饱和碳环；R13为氢、C1-C4烷基、C5-C7环烷基、2-四氢吡喃基或Si(C1-C4烷基)3；R14为(A')基团；R'13具有上述给定的R13的含义之一，或为(C)基团；是有效的光引发剂化合物。
• HYBRID PHOTOINITIATORS
  申请人：NESVADBA PETER

  公开号：US20160168279A1

  公开（公告）日：2016-06-16

  Compounds of the formula I wherein m is 1 or 2; R 1 , R 2 , R 4 and R 5 independently of one another are hydrogen, C 1 -C 4 alkyl, C 5 -C 7 cycloalkyl, phenyl, C 1 -C 4 alkoxy, C 5 -C 7 cycloalkoxy or phenoxy; R 3 , if m is 1, has one of the meanings as given above for R 1 , R 2 , R 4 and R 5 ; R 3 , if m is 2, is a divalent group; R 6 is hydrogen or C 1 -C 4 alkyl; R 7 is hydrogen, and if R 6 is hydrogen then R 7 may additionally be C 1 -C 4 alkyl; R 8 is group A or B X is O, O—CH 2 — or —O(CHR 14 )—; n is 0-10; provided that (i) if n is 0, and X is O, then R 8 is a group A; (ii) if n is other than 0, then X is O and R 8 is the group A; R 9 and R 10 independently of one another are hydrogen or C 1 -C 4 alkyl; R 11 and R 12 independently of one another are C 1 -C 4 alkyl or form together with the C atom to which they are attached a 5 to 7 membered saturated carbocyclic ring; R 13 is hydrogen, C 1 -C 4 alkyl, C 5 -C 7 cycloalkyl, 2-tetrahydropyranyl or Si(C 1 -C 4 alkyl) 3 ; R 14 is a group A′ and R′ 13 has one of the meanings as given for R 13 or is the group C are effective photoinitiator compounds.

  化合物的公式为I，其中m为1或2；R1、R2、R4和R5彼此独立地为氢、C1-C4烷基、C5-C7环烷基、苯基、C1-C4烷氧基、C5-C7环烷氧基或苯氧基；如果m为1，R3具有上述R1、R2、R4和R5中的一个意义，如果m为2，则R3是一个二价基团；R6为氢或C1-C4烷基；R7为氢，如果R6为氢，则R7还可以是C1-C4烷基；R8为A基团或BX，其中X为O、O—CH2—或—O(CHR14)—；n为0-10；前提是：（i）如果n为0且X为O，则R8为A基团；（ii）如果n不为0，则X为O且R8为A基团；R9和R10彼此独立地为氢或C1-C4烷基；R11和R12彼此独立地为C1-C4烷基，或者与它们所连接的碳原子形成一个5到7个成员的饱和碳环；R13为氢、C1-C4烷基、C5-C7环烷基、2-四氢吡喃基或Si(C1-C4烷基)3；R14为A′基团，R′13具有上述R13的一个意义，或者是C基团，是有效的光引发剂化合物。
• PARA- OR MESO-FUNCTIONALIZED AROMATIC KETONE COMPOUNDS, PREPARATION METHODS THEREOF, AND PHOTOPOLYMERIZATION INITIATORS COMPRISING THE SAME
  申请人：Shenzhen UV-Chemtech Co., Ltd

  公开号：EP2557072B1

  公开（公告）日：2017-09-20
• EP2909165A1
  申请人：——

  公开号：EP2909165A1

  公开（公告）日：2015-08-26
• LIQUID BISACYLPHOSPHINE OXIDE PHOTOINITIATOR
  申请人：IGM Group B.V.

  公开号：EP3019508B1

  公开（公告）日：2019-01-30