1,1-bis(chloromethyl)-1-silacyclobutane | 1239481-23-2

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: 1,1-bis(chloromethyl)-1-silacyclobutane
• 英文别名: 1,1-Bis(chloromethyl)siletane
• CAS: 1239481-23-2
• 化学式: C₅H₁₀Cl₂Si
• mdl: MFCD19236720
• 分子量: 169.126
• InChiKey: VRKVRPLFJIIXEF-UHFFFAOYSA-N

物化性质

• 沸点：
  76 °C(Press: 7.5 Torr)
• 密度：
  1.11±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,1-bis(chloromethyl)-1-silacyclobutane 在 sodium iodide 作用下， 以 丙酮 为溶剂， 反应 24.0h， 以93%的产率得到1,1-bis(iodomethyl)-1-silacyclobutane
  参考文献：
  名称：

  New C-functionalized silacycloalkanes (CH2)nSi(CH2X)2 and (CH2)nSi(CH2X)CH2X′ (n = 3, 4; X, X′ = functional group): Synthesis and reactivity studies of analogous silacyclobutanes and silacyclopentanes

  摘要：

  A series of novel bifunctional silacyclobutanes and silacyclopentanes of the formula types (CH2)(n)Si (CH2X)(2) and (CH2)(n)Si(CH2X)CH2X' (n = 3, 4; X, X' = functional groups) was synthesized, starting from (CH2)(4)Si(CH2Cl)(2) and (CH2)(3)Si(CH2Cl)(2), respectively. The silacyclobutanes and silacyclopentanes were structurally characterized by elemental analyses (C, H, N, S) and multinuclear NMR spectroscopy, and their reactivity was explored. The aim of these investigations was to compare the different reactivity profiles of analogous silacyclobutanes and silacyclopentanes. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2010.03.024
• 作为产物：
  描述：

  溴氯甲烷 、 1，1-二氯硅基环丁烷 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 29.0h， 以34%的产率得到1,1-bis(chloromethyl)-1-silacyclobutane
  参考文献：
  名称：

  New C-functionalized silacycloalkanes (CH2)nSi(CH2X)2 and (CH2)nSi(CH2X)CH2X′ (n = 3, 4; X, X′ = functional group): Synthesis and reactivity studies of analogous silacyclobutanes and silacyclopentanes

  摘要：

  A series of novel bifunctional silacyclobutanes and silacyclopentanes of the formula types (CH2)(n)Si (CH2X)(2) and (CH2)(n)Si(CH2X)CH2X' (n = 3, 4; X, X' = functional groups) was synthesized, starting from (CH2)(4)Si(CH2Cl)(2) and (CH2)(3)Si(CH2Cl)(2), respectively. The silacyclobutanes and silacyclopentanes were structurally characterized by elemental analyses (C, H, N, S) and multinuclear NMR spectroscopy, and their reactivity was explored. The aim of these investigations was to compare the different reactivity profiles of analogous silacyclobutanes and silacyclopentanes. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2010.03.024

文献信息

• New C-functionalized silacycloalkanes (CH2)nSi(CH2X)2 and (CH2)nSi(CH2X)CH2X′ (n = 3, 4; X, X′ = functional group): Synthesis and reactivity studies of analogous silacyclobutanes and silacyclopentanes
  作者：Dennis Troegel、W. Peter Lippert、Frank Möller、Christian Burschka、Reinhold Tacke

  DOI：10.1016/j.jorganchem.2010.03.024

  日期：2010.6

  A series of novel bifunctional silacyclobutanes and silacyclopentanes of the formula types (CH2)(n)Si (CH2X)(2) and (CH2)(n)Si(CH2X)CH2X' (n = 3, 4; X, X' = functional groups) was synthesized, starting from (CH2)(4)Si(CH2Cl)(2) and (CH2)(3)Si(CH2Cl)(2), respectively. The silacyclobutanes and silacyclopentanes were structurally characterized by elemental analyses (C, H, N, S) and multinuclear NMR spectroscopy, and their reactivity was explored. The aim of these investigations was to compare the different reactivity profiles of analogous silacyclobutanes and silacyclopentanes. (C) 2010 Elsevier B.V. All rights reserved.