Methyl α-D-galactopyranoside 6-sulfate pyridinium salt

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Methyl α-D-galactopyranoside 6-sulfate pyridinium salt
• 英文别名: pyridine;[(2R,3R,4S,5R,6S)-3,4,5-trihydroxy-6-methoxyoxan-2-yl]methyl hydrogen sulfate
• 化学式: C₅H₅N*C₇H₁₄O₉S
• 分子量: 353.35
• InChiKey: SVPOQGVBGDJASI-SAPZPLNPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.66
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  164
• 氢给体数：
  4
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  三甲基乙氧基硅烷 、 Methyl α-D-galactopyranoside 6-sulfate pyridinium salt 以 吡啶 为溶剂， 生成
  参考文献：
  名称：

  Takano, Ryo; Kanda, Takashige; Hayashi, Kaeko, Journal of Carbohydrate Chemistry, 1995, vol. 14, # 6, p. 885 - 888

  摘要：

  DOI：

文献信息

• PROCESS FOR PRODUCING DESULFATED POLYSACCHARIDE, AND DESULFATED HEPARIN
  申请人：SEIKAGAKU CORPORATION

  公开号：EP0769502A1

  公开（公告）日：1997-04-23

  This invention relates to a process for producing a desulfated polysaccharide, which comprises reacting a sulfated polysaccharide having a saccharide in which a primary hydroxyl group is sulfated, as a constituent sugar, with a silylating agent represented by the following formula (I) wherein R1s are the same or different and each represent a hydrogen atom or a halogen atom, R2 represents a lower alkyl group, and R3s are the same or different and each represent a lower alkyl group, an aryl group or a halogen atom, and a desulfated heparin obtained by this production process.

  本发明涉及一种生产脱硫多糖的工艺，该工艺包括将硫酸化多糖与硅烷化剂进行反应，硅烷化剂由下式（I）表示，硫酸化多糖的组成糖是一种初级羟基被硫酸化的糖。 其中 R1s 相同或不同，各自代表氢原子或卤素原子；R2 代表低级烷基；R3s 相同或不同，各自代表低级烷基、芳基或卤素原子、 以及通过该生产工艺获得的脱硫肝素。
• Process for producing desulfated polysaccharide, and desulfated heparin
  申请人：SEIKAGAKU CORPORATION

  公开号：US20030149253A1

  公开（公告）日：2003-08-07

  This invention relates to a process for producing a desulfated polysaccharide, which comprises reacting a sulfated polysaccharide having a saccharide in which a primary hydroxyl group is sulfated, as a constituent sugar, with a silylating agent represented by the following formula (I) 1 wherein R 1 s are the same or different and each represent a hydrogen atom or a halogen atom, R 2 represents a lower alkyl group, and R 3 s are the same or different and each represent a lower alkyl group, an aryl group or a halogen atom, and a desulfated heparin obtained by this production process.

  本发明涉及一种生产脱硫多糖的工艺，该工艺包括将硫酸化多糖与硅烷化剂进行反应，硅烷化剂由下式(I)代表，硫酸化多糖的组成糖是一个伯羟基被硫酸化的糖类。 1 其中 R 1 s 相同或不同，且各自代表氢原子或卤素原子，R 2 代表低级烷基，而 R 3 s相同或不同，各自代表低级烷基、芳基或卤素原子、 以及通过该生产工艺获得的脱硫肝素。
• PROCESS FOR PRODUCING DESULFATED POLYSACCHARIDE AND DESULFATED HEPARIN
  申请人：Seikagaku Corporation

  公开号：EP0769502B1

  公开（公告）日：2003-10-15
• Use of desulfated heparin
  申请人：SEIKAGAKU CORPORATION

  公开号：EP1371666B1

  公开（公告）日：2007-08-15
• US6140481A
  申请人：——

  公开号：US6140481A

  公开（公告）日：2000-10-31