Photoexcited Ni<sup>II</sup>–Aryl Complex-Mediated Giese Reaction of Aryl Bromides
作者:Xian-Chen He、Ke-Rong Li、Jie Gao、Jian-Ping Guan、Hong-Bin Chen、Hao-Yue Xiang、Kai Chen、Hua Yang
DOI:10.1021/acs.orglett.3c01219
日期:2023.6.9
Giese reaction of aryl bromides with electron-deficient alkenes was developed, enabled by a dual catalyst system containing NiII complex and IrIII photocatalyst. This protocol could accommodate a variety of aryl bromides and electron-deficient alkenes, delivering the conjugate adducts in up to 97% yield. The utilization of photoexcited (dtbbpy)NiII(aryl)Br intermediate as an aryl radical source allows
开发了芳基溴化物与缺电子烯烃的 Giese 反应,该反应由包含 Ni II络合物和 Ir III光催化剂的双催化剂体系实现。该协议可以容纳各种芳基溴化物和缺电子烯烃,以高达 97% 的产率提供共轭加合物。利用光激发的 (dtbbpy)Ni II (芳基)Br 中间体作为芳基自由基源,可以实现芳基卤化物的这种新型转化,从而扩大激发镍催化的化学空间。
α-Alkylation of Ketones by Trialkylamines under Heterogeneous Pd/C Catalysis
作者:Il Chul Yoon、Tae Gyun Kim、Chan Sik Cho
DOI:10.1021/om500228b
日期:2014.4.14
Ketones are regioselectively alpha-alkylated with trialkylamines in toluene at 120 degrees C in the presence of Pd/C.
Palladium-Catalyzed Heck Arylations of Allyl Alcohols in Ionic Liquids: Remarkable Base Effect on the Selectivity
Pd-catalyzed Heck arylation of allyl alcohols in tetraalkylammoniumionic liquids (ILs) can be made highly selective toward the formation of either aromatic carbonyl compounds or aromatic conjugated alcohols by carefully choosing both the IL and the base.
Palladium-Catalyzed Cross-Coupling of Indium Homoenolate with Aryl Halide with Wide Functional Group Compatibility
作者:Zhi-Liang Shen、Yin-Chang Lai、Colin Hong An Wong、Kelvin Kau Kiat Goh、Yong-Sheng Yang、Hao-Lun Cheong、Teck-Peng Loh
DOI:10.1021/ol102755q
日期:2011.2.4
An efficient palladium-catalyzed cross-coupling of indium homoenolate with arylhalide is described. The reactions proceeded efficiently in DMA at 100 °C to afford the desired products of β-aryl ketones in moderate to good yields. Various important functional groups including COR, COOR, CHO, CN, OH, and NO2 can be well tolerated in the protocol.