monododecyl phosphite | 26749-31-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: monododecyl phosphite
• 英文别名: phosphonic acid monododecyl ester；phosphorous acid monododecyl ester
• CAS: 26749-31-5
• 化学式: C₁₂H₂₇O₃P
• 分子量: 250.318
• InChiKey: MGJJRXIEFROZLZ-UHFFFAOYSA-N

物化性质

• 沸点：
  347.1±25.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.31
• 重原子数：
  16.0
• 可旋转键数：
  12.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.53
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  十二烷醇 、 monododecyl phosphite 在 四磷十氧化物 作用下， 反应 4.17h， 以65%的产率得到亚磷酸二(十二烷基)脂
  参考文献：
  名称：

  Method for the esterification of P-O components

  摘要：

  本发明涉及一种新的P-O组分酯化方法。更具体地说，本发明涉及一种新的P-O组分酯化方法，其含有至少一个P-O-H官能团，其中P-O-H官能团被转化为P-O-R官能团。根据本发明的方法可能特别适用于磷酸二酯的制造。

  公开号：

  EP2581378A1
• 作为产物：
  描述：

  十二烷醇 在 亚磷酸 作用下， 以 甲苯 为溶剂， 生成 monododecyl phosphite
  参考文献：
  名称：

  Nifant'ev,E.E. et al., Journal of applied chemistry of the USSR, 1969, vol. 42, p. 2443 - 2446

  摘要：

  DOI：

文献信息

• Trifluorothymidine derivatives, process for producing the same and anti-cancer agent containing the same
  申请人：MITSUI TOATSU CHEMICALS, Inc.

  公开号：EP0517262A1

  公开（公告）日：1992-12-09

  Novel trifluorothymidine derivatives having anti-cancer activities are disclosed. The trifluorothymidine derivatives of the present invention are represented by the formula [I]: (wherein R¹ represents hydrogen atom or C₁ - C₄ alkyl group; R² represents hydrogen atom, C₁ - C₃₀ saturated or unsaturated alkyl-substituted carbonyl group, alkyl-substituted benzoyl group, C₁ - C₄ alkyloxycarbonyl group; dimethylaminoethyloxycarbonyl group, C₁ - C₄ alkyloxymethyl group, butoxyethoxyacetyl group, benzyl group, C₁ - C₂₀ alkyl-substituted silyl group, silyl group substituted with C₁ - C₁₀ alkyl group and/or phenyl group, C₁ - C₃₀ cyclic or chain alkyl-substituted carbamoyl group, diethylaminopropylcarbamoyl group, N-alkylpiperazinylacetyl group, N-alkylprolyl group, valyl group, trityl group, alkyl-substituted phosphoryl group or propargyl group; R³ represents hydrogen atom, C₁ - C₄ alkyl group, benzyl group, benzoyl group, C₁ - C₄ alkyloxy-substituted benzoyl group, furoyl group, C₁ - C₄ alkyloxymethyl group or C₁ - C₄ alkyl-substituted carbonyl group).

  本发明揭示了具有抗癌活性的新型三氟胸腺嘧啶衍生物。本发明的三氟胸腺嘧啶衍生物由式[I]表示：（其中R¹表示氢原子或C₁-C₄烷基；R²表示氢原子，C₁-C₃₀饱和或不饱和烷基取代的羰基基团，取代苯甲酰基团，C₁-C₄烷氧羰基基团；二甲氨基乙氧羰基基团，C₁-C₄烷氧甲基基团，丁氧乙氧乙酰基基团，苯甲基团，C₁-C₂₀烷基取代的硅基团，取代C₁-C₁₀烷基和/或苯基的硅基团，C₁-C₃₀环状或链状烷基取代的氨基甲酰基团，二乙氨基丙基氨基甲酰基团，N-烷基哌嗪基乙酰基团，N-烷基丙氧基基团，瓦林基团，三苯甲基基团，取代磷酸基团或丙炔基团的烷基；R³表示氢原子，C₁-C₄烷基，苯甲基，苯甲酰基，C₁-C₄烷氧取代的苯甲酰基团，呋喃基，C₁-C₄烷氧甲基基团或C₁-C₄烷基取代的羰基基团）。
• METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND
  申请人：MARUZEN PETROCHEMICAL CO., LTD.

  公开号：US20190263847A1

  公开（公告）日：2019-08-29

  Provided is a method for producing an alkenyl phosphorus compound which can produce an alkenyl phosphorus compound efficiently even with a smaller amount of a catalyst used than that used conventionally, and further which can maintain catalytic activity to produce an alkenyl phosphorus compound in high yield even at a larger reaction scale, and which can also be applied to quantity synthesis at an industrial scale using a conventional batch reactor or continuous reactor. A method for producing an alkenyl phosphorus compound, comprising: a step of reacting a compound represented by the following formula (1): [In formula (1), R 1 represents OR 3 or R 3 , R 2 represents OR 4 or R 4 , and R 3 and R 4 represent, for example, each independently a substituted or unsubstituted alkyl group.] with a compound represented by the following formula (2): R 5 —C≡CH  (2) [In formula (2), R 5 represents, for example, a hydrogen atom, or a substituted or unsubstituted alkyl group.] to produce the phosphorus alkenyl compound presented by at least any of the following formulas (3a) or (3b): [In formulas (3a) and (3b), R 1 and R 2 have the same meaning as defined in formula (1), and R 5 has the same meaning as defined in formula (2).], In which the compound represented by formula (1) is reacted with the compound represented by formula (2) using a transition metal catalyst, and a phosphorus oxo acid compound having an intramolecular P—H bond.

  提供的是一种生产烯基磷化合物的方法，该方法即使使用的催化剂量比传统方法少，也能高效地生产烯基磷化合物，而且能够在更大的反应规模下保持催化活性，以高收率生产烯基磷化合物，并且还可以在传统的批量反应器或连续反应器中进行工业规模的量产合成。 生产烯基磷化合物的方法包括以下步骤： 将以下式（1）所表示的化合物与以下式（2）所表示的化合物反应： 式（1）中，R1代表OR3或R3，R2代表OR4或R4，R3和R4例如各自独立地代表取代或未取代的烷基基团。 式（2）中，R5例如代表氢原子，或代表取代或未取代的烷基基团。 从而产生至少以下任一式（3a）或（3b）所表示的磷烯烃化合物： 式（3a）和（3b）中，R1和R2的含义与式（1）中定义的相同，R5的含义与式（2）中定义的相同。 其中，使用过渡金属催化剂和具有分子内P-H键的磷氧酸化合物使式（1）所表示的化合物与式（2）所表示的化合物反应。
• CHROMIUM-BASED CATALYST COMPOSITION FOR PRODUCING CONJUGATED DIENE POLYMERS
  申请人：Bridgestone Corp.

  公开号：US20020115558A1

  公开（公告）日：2002-08-22

  A catalyst composition that is the combination of or the reaction product of ingredients comprising (a) a chromium-containing compound; (b) an organomagnesium compound; and (c) a silyl phosphonate. also, a process for forming conjugated diene polymers by using the catalyst composition.

  这是一个催化剂组合物的描述，由以下成分组成或反应生成：(a)含铬化合物；(b)有机镁化合物；和(c)硅基膦酸酯。同时，还提供了使用该催化剂组合物制备共轭二烯聚合物的方法。
• RESIN COMPOSITION AND APPLICATION THEREOF
  申请人：Kureha Corporation

  公开号：US20150225545A1

  公开（公告）日：2015-08-13

  The object of the present invention is to provide a resin composition that contains a near-infrared absorbent in which heat-induced discoloration is suppressed, and the resin composition is a resin composition made from a near-infrared absorbent, an antioxidant, and a resin, wherein the near-infrared absorbent is a particulate made from copper phosphonate represented by Formula (1) (wherein, R1 is a group represented by —CH2CH2-R11, and R11 indicates a hydrogen atom, an alkyl group, or an alkyl fluoride group)), and the antioxidant is at least one type selected from hindered phenol-based antioxidants and phosphorous-based antioxidants having not less than one structure represented by Formula (2) (wherein, R2 to R4 indicate alkyl groups and R5 to R8 indicate hydrogen atoms or alkyl groups.) bonded to a phosphorous atom in the molecule, and not having a structure represented by Formula (3) (wherein, R indicates an alkyl group.) bonded to the phosphorous atom in the molecule.

  本发明的目的是提供一种含有近红外吸收剂的树脂组合物，其中抑制热引起的变色，所述树脂组合物由近红外吸收剂、抗氧化剂和树脂组成，所述近红外吸收剂是由式（1）表示的磷酸铜颗粒制成（其中R1是表示为—CH2CH2-R11的基团，R11表示氢原子、烷基或烷基氟化物基团），所述抗氧化剂是至少选择一种基于受阻酚的抗氧化剂和磷酸盐的抗氧化剂，其分子中具有不少于一个式（2）表示的结构（其中R2至R4表示烷基，R5至R8表示氢原子或烷基），并且不具有式（3）表示的结构（其中R表示烷基）与分子中的磷原子结合。
• Alcohol-soluble/water-insoluble oil-containing antifreeze
  申请人：FIRST BRANDS CORPORATION

  公开号：EP0381656A1

  公开（公告）日：1990-08-08

  Antifreeze concentrate and working antifreeze composition are disclosed which comprise an alcohol, such as, for example ethylene glycol, a surface modifier, such as, for example, an organophosphate which adheres to the interior metal surfaces of an automotive cooling system, and a alcohol-soluble/­water-insoluble oil soluble in the alcohol but substantially insoluble in an aqueous solution of the alcohol, which forms a film on the surface-­modified, interior metal surfaces of the automotive cooling system.

  本发明公开了防冻剂浓缩液和工作防冻剂组合物，其中包括醇（例如乙二醇）、表面改性剂（例如有机磷酸酯）（可附着在汽车冷却系统的内部金属表面）和醇溶/水不溶油（可溶于醇，但基本不溶于醇的水溶液），后者可在表面改性的汽车冷却系统内部金属表面上形成一层膜。