1,1,3-三乙氧基-丁烷 | 5870-82-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1,1,3-三乙氧基-丁烷
• 英文名称: 1,1,3-triethoxy-butane
• 英文别名: 3-ethoxy-butyraldehyde diethyl acetal；3-Aethoxy-butyraldehyd-diaethylacetal；1.1.3-Triaethoxy-butan；α.α.γ-Tri-aethoxy-butan；β-Aethoxy-butyraldehyd-diaethylacetal；1,1,3-Triethoxybutane
• CAS: 5870-82-6
• 化学式: C₁₀H₂₂O₃
• 分子量: 190.283
• InChiKey: MDIBXLWYZGZAKL-UHFFFAOYSA-N

物化性质

• 沸点：
  190 °C
• 密度：
  0.876 g/cm3
• LogP：
  1.963 (est)
• 保留指数：
  1310

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

SDS

Version 1.0
Regulation (EC) No 1907/2006

---

1 - Product and Company Information

---

Product Name 1,1,3-TRIETHOXYBUTANE-

---

2 - Hazards Identification

---

SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Not hazardous according to Directive 67/548/EEC.

---

3 - Composition/Information on Ingredients

---

Product Name CAS # EC no Annex I
Index Number
1,1,3-TRIETHOXYBUTANE 5870-82-6 None None
Formula C10H22O3
Molecular Weight 190,2800 AMU
Synonyms Butyraldehyde, 3-ethoxy-, diethyl acetal (8CI) *
1,1,3-Triethoxybutane

---

4 - First Aid Measures

---

AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.

---

5 - Fire Fighting Measures
ALDRICH www.molbase.com

---

EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

---

6 - Accidental Release Measures

---

METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.

---

7 - Handling and Storage

---

HANDLING
Directions for Safe Handling: Avoid inhalation. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed.

---

8 - Exposure Controls / Personal Protection

---

ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US)
or CEN (EU). Respiratory protection is not required. Where
protection is desired, use multi-purpose combination (US) or type
ABEK (EN 14387) respirator cartridges.
Hand Protection: Protective gloves.
Eye Protection: Chemical safety goggles.

---

9 - Physical and Chemical Properties

---

Appearance Physical State: Liquid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
ALDRICH www.molbase.com
Explosion Limits N/A
Vapor Pressure N/A
Partition Coefficient Log Kow: 2,184
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A

---

10 - Stability and Reactivity

---

STABILITY
Materials to Avoid: Acids, Oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur

---

11 - Toxicological Information

---

RTECS NUMBER: EK7000000
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.

---

12 - Ecological Information

---

No data available.

---

13 - Disposal Considerations

---

SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.

---

14 - Transport Information

---

RID/ADR
Non-hazardous for road transport.
ALDRICH www.molbase.com
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.

---

15 - Regulatory Information

---

Not hazardous according to Directive 67/548/EEC.
Caution: Substance not yet fully tested (EU).

---

16 - Other Information

---

WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2010 Co. License granted to make
unlimitedpaper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
ALDRICH www.molbase.com

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  1,1,3-三乙氧基-丁烷 在 三氯化硼 、 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 6.5h， 生成 tert-butyl-[(2S,3S)-3-chloro-2-(1,3-diethoxybutoxy)-6-trimethylsilylhept-6-enoxy]-dimethylsilane
  参考文献：
  名称：

  Total synthesis of (-)-laurenyne. Use of acetal-initiated cyclizations to prepare functionalized eight-membered cyclic ethers

  摘要：

  DOI：

  10.1021/ja00215a040
• 作为产物：
  描述：

  乙缩醛 在 zinc(II) chloride 作用下， 生成 1,1,3-三乙氧基-丁烷
  参考文献：
  名称：

  Kutscherow; Jufit, 1959, p. 197,199

  摘要：

  DOI：

文献信息

• LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS
  申请人：INTERMUNE, INC.

  公开号：US20140200215A1

  公开（公告）日：2014-07-17

  Compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or diagnose diseases, disorders, or conditions associated with one or more of the lysophosphatidic acid receptors are provided.

  提供的是化合物、制造这些化合物的方法、包含这些化合物的药物组合物和药品，以及使用这些化合物来治疗、预防或诊断与一个或多个溶血磷脂酸受体相关的疾病、失调或状况的方法。
• [EN] NEW FROTHERS FOR MINERALS RECOVERY<br/>[FR] NOUVEAUX AGENTS MOUSSANTS POUR LA RÉCUPÉRATION DE MINÉRAUX
  申请人：SOLVAY

  公开号：WO2021160860A1

  公开（公告）日：2021-08-19

  The present invention pertains to a composition comprising at least one compound of formula (I) and to the use of said composition for recovering value minerals from ore and other feedstocks by flotation (formula (I)).

  本发明涉及一种包含至少一种式(I)化合物的组合物，以及利用该组合物从矿石和其他原料中通过浮选回收有价值矿物的用途（式(I)）。
• [EN] NEW FROTHERS FOR MINERALS RECOVERY AND METHODS OF MAKING AND USING SAME<br/>[FR] NOUVEAUX AGENTS MOUSSANTS POUR LA RÉCUPÉRATION DE MINÉRAUX ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION
  申请人：SOLVAY

  公开号：WO2021160864A1

  公开（公告）日：2021-08-19

  The present invention pertains to a composition comprising at least one compound of formula (I) and to the use of said composition for recovering value minerals from ore and other feedstocks by flotation.

  本发明涉及一种包含至少一种式(I)化合物的组合物，以及利用该组合物从矿石和其他原料中通过浮选回收有价值矿物的用途。
• [EN] COMPOUNDS AND COMPOSITIONS FOR USE AS FOAMING OR FROTHING AGENTS IN ORE AND COAL FLOTATION<br/>[FR] COMPOSES ET COMPOSITIONS POUVANT ETRE UTILISES EN TANT QU'AGENTS GONFLANT OU MOUSSANT DANS LA FLOTTATION D'UN MINERAI ET DU CHARBON
  申请人：HUNTSMAN CORP AUSTRALIA PTY LT

  公开号：WO2004052815A1

  公开（公告）日：2004-06-24

  Compounds of formula (I) wherein R1 and R2 are each independently C1-C2 alkyl, and m is 1, 2, 3, 4, or 5 and compositions of formula (II) wherein R1 and R2 are each independently C1-C4 alkyl, and n is an integer >_0 and wherein the average molar value of n for the total of the compounds of formula (II) in said composition is in the range of (1) to (3) and methods for production thereof.

  式（I）中R1和R2分别独立为C1-C2烷基，m为1、2、3、4或5，以及式（II）中R1和R2分别独立为C1-C4烷基，n为整数>_0，其中所述组合物中式（II）的化合物总体的n的平均摩尔值在（1）至（3）范围内，以及其生产方法。
• METHOD FOR PRODUCING N-METHYL-N-VINYLACETAMIDE HAVING IMPROVED STABILITY AND POLYMERIZABILITY
  申请人：Showa Denko K.K.

  公开号：EP2239250A1

  公开（公告）日：2010-10-13

  The present invention relates to a method for producing N-methyl-N-vinylacetamide, which comprises a step for controlling the N-1,3-butadienyl-N-methylacetamide content in N-methyl-N-vinylacetamide to 0.01-150 ppm. This method enables production of N-methyl-N-vinylacetamide having a stable quality, which can be controlled in stability and polymerizability as a monomer. N-methyl-N-vinylacetamide produced by the method enables production of an N-methyl-N-vinylacetamide polymer having stable physical properties such as a molecular weight.

  本发明涉及一种生产N-甲基-N-乙烯基乙酰胺的方法，其中包括控制N-1,3-丁二烯基-N-甲基乙酰胺在N-甲基-N-乙烯基乙酰胺中的含量为0.01-150 ppm的步骤。该方法使得能够生产具有稳定质量的N-甲基-N-乙烯基乙酰胺，可以在稳定性和聚合性作为单体中进行控制。通过该方法生产的N-甲基-N-乙烯基乙酰胺能够生产具有稳定物理性质，如分子量的N-甲基-N-乙烯基乙酰胺聚合物。