1,4-cycloheptanediol | 31351-04-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,4-cycloheptanediol
• 英文别名: cis-1,4-dihydrocycloheptane；cis-1,4-Cycloheptandiol；cis-cycloheptane-1,4-diol；cis-Cycloheptan-1,4-diol；(1S,4R)-cycloheptane-1,4-diol
• CAS: 31351-04-9
• 化学式: C₇H₁₄O₂
• 分子量: 130.187
• InChiKey: ZXJWWZPUERUHLC-KNVOCYPGSA-N

物化性质

• 熔点：
  68.4-70.0 °C
• 沸点：
  259.4±8.0 °C(Predicted)
• 密度：
  1.101±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,3-环庚二烯 在 乙醇 、 Eosin Y 、 氧气 、 铂 作用下， 生成 1,4-cycloheptanediol
  参考文献：
  名称：

  Proximity Effects. X. cis-1,4-Cycloheptanediol from Solvolysis of Cycloheptene Oxide¹

  摘要：

  DOI：

  10.1021/ja01580a047

文献信息

• AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS
  申请人：Novira Therapeutics, Inc.

  公开号：US20150197493A1

  公开（公告）日：2015-07-16

  Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

  本文提供了一些用于治疗HBV感染的化合物，以及其药物组合物和抑制、抑制或预防受试者HBV感染的方法。
• CoTPP-catalyzed reaction of saturated bicyclic endoperoxides
  作者：Metin Balci、Nihat Akbulut

  DOI：10.1016/s0040-4020(01)96533-0

  日期：1985.1

  Saturated bicyclic endoperoxides were exposed to CoTPP (Cobalt-meso-tetraphenylporphyrine) in chloroform, the peroxide bond was cleaved and a mixture of products arising from fragmentation and reduction obtained.

  将饱和的双环内过氧化物暴露于氯仿中的CoTPP（钴-间位-四苯基卟啉）中，将过氧化物键裂解，并获得由裂解和还原产生的产物混合物。
• AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS
  申请人：Novira Therapeutics, Inc.

  公开号：US20150197533A1

  公开（公告）日：2015-07-16

  Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

  本文提供了一些化合物，用于治疗需要治疗乙型肝炎感染的患者，以及这些化合物的药物组合物和抑制、抑制或预防患者乙型肝炎感染的方法。
• First catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP2048167A2

  公开（公告）日：2009-04-15

  An electron withdrawing group-containing metal compound (I) of the formula [7]: wherein M3 represents an atom of Group XII, Groups III to XI or the lanthanide series of the Periodic Table; when a plural number of M3's exist, they may be the same as or different from each other; T3 represents an atom of Group XIV, XV or XVI of the Periodic Table; when a plural number of T3's exist, they may be the same as or different from each other; R5 represents an electron-withdrawing group or a group containing an electron-withdrawing group; when a plural number of R5's exist, they may be the same as or different from each other; R6 represents a hydrocarbon group; when a plural number of R6's exist they may be the same as or different from each other; "g" represents a valence of M3; "s" represents a valence of T3; and "h" represents a number of 1 or more.

  式[7]的含电子萃取基团的金属化合物（I）： 其中 M3 代表元素周期表中第 XII 族、第 III 族至第 XI 族或镧系元素的原子；当存在多个 M3 时，它们可以彼此相同或不同；T3 代表元素周期表中第 XIV 族、第 XV 族或第 XVI 族的原子；当存在多个 T3 时，它们可以彼此相同或不同；R5 代表抽电子基团或含有抽电子基团的基团；当存在多个 R5 时，它们可以彼此相同或不同；R6 代表烃基；当存在多个 R6 时，它们可以彼此相同或不同；"g "代表 M3 的化合价；"s "代表 T3 的化合价；"h "代表 1 或以上的数字。
• Second catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP2048170A2

  公开（公告）日：2009-04-15

  An electron withdrawing group-containing metal compound (I) of formula [8]:          M4(X1R7i)t R8j-t     [8] wherein M4 represents an atom of Group XII, Groups III to XI or the lanthanide series of the Periodic Table; X1 represents an atom of Group XIV, XV or XVI of the Periodic Table; when a plural number of X1's exist, they may be the same as or different from each other; R7 represents an electron-withdrawing group or a group containing an electron-withdrawing group; when a plural number of R7's exist, they may be the same as or different from each other; R8 represents a hydrogen atom, a halogen atom or a hydrocarbon group; when a plural number of R8's exist, they may be the same as or different from each other; "j" represents a valence of M4; "t" represents a number satisfying 0

  式[8]的含电子萃取基团的金属化合物（I）： M4(X1R7i)t R8j-t [8]. 其中 M4 代表元素周期表中第 XII 族、第 III 族至第 XI 族或镧系元素的原子；X1 代表元素周期表中第 XIV 族、第 XV 族或第 XVI 族的原子；当存在多个 X1 时，它们可以彼此相同或不同；R7 代表抽电子基团或含有抽电子基团的基团；R8代表氢原子、卤素原子或碳氢基团；当存在复数个R8时，它们可以彼此相同或不同；"j "代表M4的化合价；"t "代表满足0