2,7-dicyano-9-methylcarbazole | 200878-47-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2,7-dicyano-9-methylcarbazole
• 英文别名: 9-Methylcarbazole-2,7-dicarbonitrile
• CAS: 200878-47-3
• 化学式: C₁₅H₉N₃
• 分子量: 231.257
• InChiKey: OFHGODBOPGCZAW-UHFFFAOYSA-N

物化性质

• 沸点：
  411.1±38.0 °C(Predicted)
• 密度：
  1.20±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  52.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,2-diaminoethane dihydrochloride 、 2,7-dicyano-9-methylcarbazole 反应 1.25h， 以19%的产率得到2,7-bis(2-imidazolinyl)-9-methylcarbazole dihydrochloride
  参考文献：
  名称：

  Anti-Pneumocystis carinii pneumonia activity of dicationic carbazoles

  摘要：

  A series of 2,7- and 3,6-bis cationic carbazoles was synthesized and evaluated for activity against a rat model of Pneumocystis carinii pneumonia (PCP). The compounds were also tested for inhibition of topoisomerase II and binding to DNA. Several of the compounds proved to be more potent and less toxic than a standard anti-PCP drug (pentamidine). While no quantitative correlation was seen between anti-PCP activity, topoisomerase inhibition and DNA binding, a minimal level of DNA binding was found to be necessary for antimicrobial activity.

  DOI：

  10.1016/s0223-5234(99)80064-6
• 作为产物：
  描述：

  4,4'-二溴-2,2'-二硝基联苯 在 sodium hydride 、 tin(ll) chloride 作用下， 以 乙醇 、 磷酸 、 N,N-二甲基甲酰胺 为溶剂， 反应 55.5h， 生成 2,7-dicyano-9-methylcarbazole
  参考文献：
  名称：

  Anti-Pneumocystis carinii pneumonia activity of dicationic carbazoles

  摘要：

  A series of 2,7- and 3,6-bis cationic carbazoles was synthesized and evaluated for activity against a rat model of Pneumocystis carinii pneumonia (PCP). The compounds were also tested for inhibition of topoisomerase II and binding to DNA. Several of the compounds proved to be more potent and less toxic than a standard anti-PCP drug (pentamidine). While no quantitative correlation was seen between anti-PCP activity, topoisomerase inhibition and DNA binding, a minimal level of DNA binding was found to be necessary for antimicrobial activity.

  DOI：

  10.1016/s0223-5234(99)80064-6

文献信息

• [EN] SEVEN-MEMBERED RING COMPOUNDS<br/>[FR] COMPOSÉS CYCLIQUES À SEPT ANNEAUX
  申请人：IDEMITSU KOSAN CO

  公开号：WO2017178864A1

  公开（公告）日：2017-10-19

  The present invention relates to compounds of formula (I); a process for their production and their use in electronic devices, especially electroluminescent devices. When used as charge transport material and/or host material for phosphorescent emitters in electroluminescent devices, the compounds of formula I may provide improved efficiency, stability, manufacturability and/or spectral characteristics of electroluminescent devices.

  本发明涉及式(I)的化合物；它们的生产过程以及它们在电子设备中的应用，特别是电致发光器件。当作为电荷传输材料和/或荧光发射体在电致发光器件中使用时，式(I)的化合物可能提供电致发光器件的效率、稳定性、可制造性和/或光谱特性的改进。
• NITRILE SUBSTITUTED DIBENZOFURANS
  申请人：Idemitsu Kosan Co., Ltd.

  公开号：US20160248026A1

  公开（公告）日：2016-08-25

  The present invention relates to compounds of formula a process for their production and their use in electronic devices, especially electroluminescent devices. When used as electron transport material, hole blocking material and/or host material for phosphorescent emitters in electroluminescent devices, the compounds of formula I may provide improved efficiency, stability, manufacturability, or spectral characteristics of electroluminescent devices.

  本发明涉及公式I的化合物、其生产方法以及它们在电子器件中的应用，特别是在电致发光器件中作为电子输运材料、阻挡空穴材料和/或荧光发射体的基体材料时，公式I的化合物可以提供电致发光器件的效率、稳定性、可制造性或光谱特性的改善。
• ORGANIC LIGHT-EMITTING ELEMENT, AND LIGHT-EMITTING MATERIAL AND COMPOUND FOR USE THEREIN
  申请人：Toyobo Co., Ltd.

  公开号：EP3511321A1

  公开（公告）日：2019-07-17

  Using a compound that contains a structure where a carbazol-9-yl group substituted with a perfluoroalkyl group at the 2-position and the 7-position and a structural unit having a positive Hammett constant σp (but excluding an aromatic hydrocarbon group) bond to each other directly or via a π-conjugated linking group, wherein at least a part of the carbazol-9-yl group and at least a part of the structural unit having a positive Hammett constant σp and, if any, the π-conjugated linking group form a π-electron conjugated system, an organic light emitting device having a high emission efficiency can be provided.

  使用一种化合物，该化合物含有在 2 位和 7 位上被全氟烷基取代的咔唑-9-基团和具有正哈米特常数 σp 的结构单元（但不包括芳香烃基）直接或通过 π-共轭连接基团相互键合的结构、其中至少一部分咔唑-9-基团和至少一部分具有正哈米特常数σp 的结构单元以及（如有）π-共轭连接基团形成一个 π-电子共轭体系，可提供一种具有高发射效率的有机发光器件。
• Benzimidazolo[1,2-A]benzimidazole carrying aryl- or arylnitril groups for organic light emitting diodes
  申请人：IDEMITSU KOSAN CO., LTD.

  公开号：US10689385B2

  公开（公告）日：2020-06-23

  Novel benzimidazolo[1,2-a]benzimidazoles carrying aryl- or heteroarylnitril groups, an electronic device, comprising said novel benzimidazolo[1,2-a]benzimidazoles carrying aryl- or heteroarylnitril groups, which is preferably an electroluminescent device, a charge transport layer, a charge/exciton blocker layer, or an emitting layer comprising said novel benzimidazolo[1,2-a]benzimidazoles carrying aryl- or heteroarylnitril groups, an apparatus selected from the group consisting of stationary visual display units; mobile visual display units; illumination units; key-boards; items of clothing; furniture; wallpaper, comprising said organic electronic device, or said charge transport layer, said charge/exciton blocker layer, or said emitting layer.

  携带芳基或杂芳基氮基团的新型苯并咪唑并[1,2-a]苯并咪唑，包括所述携带芳基或杂芳基氮基团的新型苯并咪唑并[1,2-a]苯并咪唑的电子装置，最好是电致发光装置、电荷传输层、电荷/激子阻挡层或发光层，其中包含上述携带芳基或杂芳基氮基团的新型苯并咪唑并[1,2-a]苯并咪唑； 选自固定视觉显示装置组的装置；移动视觉显示装置；照明装置；键盘；服装；家具；壁纸，包括所述有机电子装置，或所述电荷传输层、电荷/激子阻挡层或所述发射层。
• Seven-membered ring compounds
  申请人：Idemitsu Kosan Co., Ltd.

  公开号：US10968229B2

  公开（公告）日：2021-04-06

  The present invention relates to compounds of formula (I); a process for their production and their use in electronic devices, especially electroluminescent devices. When used as charge transport material and/or host material for phosphorescent emitters in electroluminescent devices, the compounds of formula I may provide improved efficiency, stability, manufacturability and/or spectral characteristics of electroluminescent devices.

  本发明涉及式（I）化合物；其生产工艺及其在电子设备，特别是电致发光设备中的用途。当用作电致发光器件中电荷传输材料和/或磷光发光体的主材料时，式 I 化合物可提高电致发光器件的效率、稳定性、可制造性和/或光谱特性。