1-乙基-3-甲基咪唑硫酸乙酯 | 342573-75-5

• 物质功能分类: 化学试剂 - 有机试剂 - 离子液体
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 中文名称: 1-乙基-3-甲基咪唑硫酸乙酯
• 中文别名: 1-乙基-3-甲基咪唑乙基磺酸盐；1-乙基-3-甲基咪唑硫酸乙酯,99%；螺旋双吡咯四氟硼酸盐；1-乙基-3-甲基咪唑硫酸乙酯盐
• 英文名称: 1-ethyl-3-methylimidazol-3-ium ethyl sulfate
• 英文别名: 1-ethyl-3-methylimidazolium ethyl sulfate；1-ethyl-3-methylimidazolium ethylsulphate；3-ethyl-1-methylimidazolium ethyl sulfate；1-ethyl-3-methyl-1H-imidazolium ethylsulfate；ECOENG 212；[EMIm][EtSO₄]；EMIM ethyl sulfate；[EMIM][ES]；EMIMESU；EMIES；1-Ethyl-3-Methylimidazolium Ethylsulfate；1-ethyl-3-methylimidazol-3-ium;ethyl sulfate
• CAS: 342573-75-5
• 化学式: C₂H₅O₄S*C₆H₁₁N₂
• 分子量: 236.292
• InChiKey: VRFOKYHDLYBVAL-UHFFFAOYSA-M

物化性质

• 熔点：
  <65°C
• 密度：
  1.24
• 闪点：
  162 °C
• 物理描述：
  Liquid
• 稳定性/保质期：
  避氧化物 (空白行忽略)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.18
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  83.6
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• TSCA：
  Yes
• 危险品标志：
  Xi
• 安全说明：
  S26,S36
• 危险类别码：
  R36/37/38
• WGK Germany：
  1
• 海关编码：
  2933290090
• 包装等级：
  III
• 危险类别：
  8,6.1
• 危险性防范说明：
  P201,P280,P303+P361+P353,P304+P340+P310,P305+P351+P338+P310,P308+P313
• 危险品运输编号：
  2922
• 危险性描述：
  H302,H311,H314,H340,H350
• 储存条件：
  保存方法：密闭、阴凉、通风干燥处。

SDS

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Section 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE
Product identifiers
Product name : 1-Ethyl-3-methylimidazolium ethyl sulfate
CAS-No. : 342573-75-5
Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances

---

Section 2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008
This substance is not classified as dangerous according to Directive 67/548/EEC.
Label elements
The product does not need to be labelled in accordance with EC directives or respective national laws.
Caution - substance not yet tested completely.
Other hazards - none

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substances
Synonyms : BASIONIC® LQ 01
Formula : C8H16N2O4S
Molecular Weight : 236,29 g/mol

---

Section 4. FIRST AID MEASURES
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
no data available

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Section 5. FIREFIGHTING MEASURES
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx), Sulphur oxides
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

---

Section 6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapors, mist or gas.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed
containers for disposal.
Reference to other sections
For disposal see section 13.

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Section 7. HANDLING AND STORAGE
Precautions for safe handling
Normal measures for preventive fire protection.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
hygroscopic Store under inert gas.
Specific end uses
no data available

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Section 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards
such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
impervious clothing, The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup
to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).

---

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Information on basic physical and chemical properties
a) Appearance Form: viscous
Colour: light yellow
b) Odour sweet
c) Odour Threshold no data available
d) pH 8,2 at 100 g/l
e) Melting point/freezing < -30 °C
point
f) Initial boiling point and no data available
boiling range
g) Flash point 154,5 °C - ISO 2719
h) Evaporation rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower no data available
flammability or
explosive limits
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density 1.239 g/cm3 at 20 °C
n) Water solubility completely soluble
o) Partition coefficient: n- log Pow: < 0,3
octanol/water
p) Autoignition no data available
temperature
q) Decomposition no data available
temperature
r) Viscosity 98,7 mm2/s at 25 °C -
s) Explosive properties no data available
t) Oxidizing properties no data available
Other safety information
Solubility in other Alcohol
solvents
Surface tension 72 mN/m at 20 °C

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Section 10. STABILITY AND REACTIVITY
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
Other decomposition products - no data available

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Section 11. TOXICOLOGICAL INFORMATION
Information on toxicological effects
Acute toxicity
LD50 Oral - rat - > 2.000 mg/kg
LC50 Dermal - rat - > 2.000 mg/kg
Skin corrosion/irritation
Skin - rabbit - No skin irritation - OECD Test Guideline 404
Serious eye damage/eye irritation
Eyes - rabbit - No eye irritation - OECD Test Guideline 405
Respiratory or skin sensitization
mouse - Did not cause sensitization on laboratory animals.
Germ cell mutagenicity
Tests on bacterial or mammalian cell cultures did not show mutagenic effects.
Carcinogenicity
no data available
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
Specific target organ toxicity - repeated exposure
The substance or mixture is not classified as specific target organ toxicant, repeated exposure.
Aspiration hazard
no data available
Potential health effects
Inhalation May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion May be harmful if swallowed.
Skin May be harmful if absorbed through skin. May cause skin irritation.
Eyes
May cause eye irritation.
Additional Information
RTECS: Not available

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Section 12. ECOLOGICAL INFORMATION
Toxicity
Toxicity to fish static test LC50 - Cyprinus carpio (Carp) - > 100 mg/l - 96 h
Method: ISO 7346/1
Toxicity to daphnia and static test LC50 - Daphnia - > 100 mg/l - 48 h
other aquatic Method: OECD Test Guideline 202
invertebrates
Toxicity to algae Growth inhibition - SELENASTRUM - > 100 mg/l
Method: ISO 8692
Toxicity to bacteria LC50 - other microorganisms - > 100 mg/l - 0,5 h
Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Method: Tested according to Directive 92/69/EEC.
Remarks: According to the results of tests of biodegradability this product is not
readily biodegradable.
Physico-chemical Remarks: Not readily eliminated from water.
removability
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
no data available
Other adverse effects
no data available

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Section 13. DISPOSAL CONSIDERATIONS
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed
professional waste disposal service to dispose of this material.
Contaminated packaging
Dispose of as unused product.

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Section 14. TRANSPORT INFORMATION
UN number
ADR/RID: - IMDG: - IATA: -
UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
Packaging group
ADR/RID: - IMDG: - IATA: -
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
no data available

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Section 15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
Chemical Safety Assessment
no data available

---

Section 16. OTHER INFORMATION
Further information
Copyright 2012 Co. LLC. License granted to make unlimited paper copies for internal use
only.
The above information is believed to be correct but does not purport to be all inclusive and shall be
used only as a guide. The information in this document is based on the present state of our knowledge
and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Corporation and its Affiliates shall not be held
liable for any damage resulting from handling or from contact with the above product. See
and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.

制备方法与用途

应用

1-乙基-3-甲基咪唑硫酸乙酯[EMIM][ESO4]具有良好的导电性和电化学稳定性，能够与多种材料互溶，并可用作涂料、油墨和高分子材料等行业中的离子液体抗静电剂。此外，它不含卤素，对设备的腐蚀性较小，适合作为有机萃取剂或溶剂使用。

反应信息

• 作为反应物：
  描述：

  1-乙基-3-甲基咪唑硫酸乙酯 在 水 作用下， 反应 77.0h， 生成 1-ethyl-3-methylimidazolium n-butyl sulfate
  参考文献：
  名称：

  基于烷基硫酸盐的质子和非质子离子液体是否对水和酒精稳定？热力学方法

  摘要：

  在开发涉及这些新型材料的任何工业应用和方法之前，了解在其他分子（例如水）存在下化学稳定性随离子液体（ILs）温度变化的知识至关重要。在较大的温度范围和组成范围内，液相平衡和密度可以提供有关IL纯度和化学稳定性的基本信息。IL科学界要求从参考数据中获取准确的测量值。在这项工作中，研究了在水和各种醇（甲醇，乙醇，1-丁醇和1-辛醇）存在下，不同的基于烷基硫酸盐的离子液体的稳定性，以了解它们在高达423.15 K的温度下的稳定性。分别进行水解和酯交换反应。根据这项调查，很明显，基于硫酸甲酯和硫酸乙酯的离子液体在水的存在下不稳定，因为毫无疑问地观察到了硫酸甲酯或硫酸乙酯阴离子水解为甲醇或乙醇和氢化阴离子。这样的观察可以帮助解释不同群体在文献中发表的物理性质的差异。此外，似乎热力学平衡过程驱动了这些水解反应。换句话说，这些水解反应实际上是可逆的，从而提供了通过基于硫酸氢的IL与相应的醇（甲醇或乙醇）

  DOI：

  10.1021/jp312241h
• 作为产物：
  描述：

  1-ethyl-3-methylimidazolium octyl sulfate 在 水 作用下， 反应 1479.0h， 生成 1-乙基-3-甲基咪唑硫酸乙酯
  参考文献：
  名称：

  基于烷基硫酸盐的质子和非质子离子液体是否对水和酒精稳定？热力学方法

  摘要：

  在开发涉及这些新型材料的任何工业应用和方法之前，了解在其他分子（例如水）存在下化学稳定性随离子液体（ILs）温度变化的知识至关重要。在较大的温度范围和组成范围内，液相平衡和密度可以提供有关IL纯度和化学稳定性的基本信息。IL科学界要求从参考数据中获取准确的测量值。在这项工作中，研究了在水和各种醇（甲醇，乙醇，1-丁醇和1-辛醇）存在下，不同的基于烷基硫酸盐的离子液体的稳定性，以了解它们在高达423.15 K的温度下的稳定性。分别进行水解和酯交换反应。根据这项调查，很明显，基于硫酸甲酯和硫酸乙酯的离子液体在水的存在下不稳定，因为毫无疑问地观察到了硫酸甲酯或硫酸乙酯阴离子水解为甲醇或乙醇和氢化阴离子。这样的观察可以帮助解释不同群体在文献中发表的物理性质的差异。此外，似乎热力学平衡过程驱动了这些水解反应。换句话说，这些水解反应实际上是可逆的，从而提供了通过基于硫酸氢的IL与相应的醇（甲醇或乙醇）

  DOI：

  10.1021/jp312241h
• 作为试剂：
  描述：

  (benzyloxy)benzene 在 1-乙基-3-甲基咪唑硫酸乙酯 、 叔丁醇 作用下， 199.84 ℃ 、2.0 MPa 条件下， 反应 2.0h， 生成 乙醇 、 甲苯 、 苯甲醇 、 苯 、 苯酚
  参考文献：
  名称：

  新型液体状纳米颗粒有机杂化溶剂对木质素模型化合物进行热化学解聚的光谱研究

  摘要：

  这项研究报告了使用纳米颗粒有机杂化材料（NOHMs）对木质素模型化合物的热化学转化。NOHMs最近已发展成为一种新兴的自悬浮纳米颗粒溶剂系统，该系统通过将有机低聚物或聚合物（冠层）离子或共价接枝到表面改性的无机纳米颗粒（核）上而制得。由于NOHMs的蒸气压微不足道，并且具有调节理化性质的能力，因此对于木质素热化学转化过程，它们可能是很有前途的催化溶剂。用合成的NOHM在473 K的高温下实现木质素模型化合物的热化学转化，并将结果与​​离子液体[EMIM] [ESO 4 ]的情况进行比较。]。木质素模型化合物的断裂部分通过ATR FT-IR和2D COZY NMR光谱定性鉴定。结果表明，与[EMIM] [ESO 4 ]相比，NOHM更有效地分解了木质素模型化学物质的C-O和/或C-C键。

  DOI：

  10.1021/acs.oprd.8b00282

文献信息

• Studies of Volumetric and Viscosity Properties in Aqueous Solutions of Imidazolium Based Ionic Liquids at Different Temperatures and at Ambient Pressure
  作者：Pankaj D. Patil、Vasim R. Shaikh、Gaurav R. Gupta、Dilip G. Hundiwale、Kesharsingh J. Patil

  DOI：10.1007/s10953-019-00845-7

  日期：2019.1

  Jones–Dole equation and Vand’s equations. Positive viscosity A and B coefficients were observed for both studied ILs, while the D coefficients were also found to be necessary, showing specific behavior depending upon the solute–solute interactions. Calculations of the B coefficients for anions are reported. The application of Vand’s equation to the viscosity data enabled us to calculate the Einstein–Simha

  离子液体 (ILs) 1,3-二甲基咪唑甲基硫酸盐 [MIm][MeSO4] 和 1-乙基-3-甲基咪唑乙基硫酸盐 [EMIm][EtSO4] 已合成并通过 1H NMR、13C NMR、质谱光谱法、TGA 和 DSC 方法。[MIm][MeSO4]（0.02458 至 0.18922 mol·kg-1）和 [EMIm][EtSO4]（0.01044 至 0.21261 mol·kg-1）的二元水溶液的密度和粘度报告在 (293.15, 5 和 298) 303.15) K 和在环境压力下。在所研究的浓度下计算所研究的 IL 的表观和部分摩尔体积。所研究的离子液体的极限部分摩尔体积是使用适当的外推方法获得的。还获得了 298.15 K 时的极限表观摩尔膨胀率值。通过应用琼斯-多尔方程和范德方程来分析相对粘度数据。对于两个研究的 IL，观察到正粘度 A 和 B 系数，而 D 系数也被发现是必要的，显示出取决于溶质
• 一种利用[Rmim][OSO2OR]-Lewis酸离子液 体系合成红景天苷的方法
  申请人：枣庄学院

  公开号：CN107880085B

  公开（公告）日：2021-04-09

  本发明属于催化合成技术领域，具体涉及一种利用[Rmim][OSO2OR]‑Lewis酸离子液体系合成红景天苷的方法。该方法利用离子液体[Rmim][OSO2OR]合成红景天苷化合物。本发明提供的离子液体的合成仅需一步反应，且在离子液体合成反应中原料的原子得到100%的利用，是一个操作简便的原子经济性反应。本发明提供的方法环境友好、反应条件温和、后处理简单，解决现有离子液体系催化糖基三氯乙酰亚胺酯给体O‑糖苷化过程中所用离子液体的合成繁琐、热能消耗、原子浪费以及非原子经济性反应所造成的环境污染等问题，同时解决了现有有机溶剂中进行红景天苷类药物化学合成所造成的环境污染、后处理繁琐等问题。
• Functionalized Ionic Liquids and Their Applications
  申请人：Materials Modification Inc

  公开号：US20140287640A1

  公开（公告）日：2014-09-25

  Disclosure of functionalized ionic liquids. Use of disclosed ionic liquids as solvent for carbon dioxide. Use of disclosed ionic liquids as flame retardant. Use of disclosed ionic liquids for coating fabric to obtain flame retardant fabric.

  功能化离子液体的披露。披露的离子液体用作二氧化碳溶剂。披露的离子液体用作阻燃剂。利用披露的离子液体涂覆织物以获得阻燃织物。
• IONIC LIQUID AS LUBRICATING OIL BASE STOCKS, COBASE STOCKS AND MULTIFUNCTIONAL FUNCTIONAL FLUIDS
  申请人：ExxonMobil Research and Engineering Company

  公开号：US20150045266A1

  公开（公告）日：2015-02-12

  A composition including an ionic liquid alkyl ammonium salt (e.g., tetraalkylammonium cation and bis(trifluoromethanesulfonyl)imide anion) or an ionic liquid imidazolium salt (e.g., 1,3-dialkylimidazolium cation and bis(trifluoromethanesulfonyl)imide anion), that have a structure sufficient to exhibit at least partial solubility in one or more Group I-V base stocks. The disclosure also relates to a lubricating oil base stock and lubricating oil containing the composition, a multifunctional functional fluid containing the composition, and a method for improving solubility of an ionic liquid in a lubricating oil by using as the lubricating oil a formulated oil including a lubricating oil base stock as a major component, and an ionic liquid alkylammonium salt cobase stock, or an ionic liquid imidazolium salt cobase stock, as a minor component.

  一种包括离子液体烷基铵盐（例如，四烷基铵阳离子和双(三氟甲磺酰)亚胺阴离子）或离子液体咪唑盐（例如，1,3-二烷基咪唑阳离子和双(三氟甲磺酰)亚胺阴离子）的组合物，具有足够的结构以在一种或多种I-V族碱基油中至少部分溶解。该公开还涉及含有该组合物的润滑油基础油和润滑油，含有该组合物的多功能功能液体，以及通过使用作为润滑油的配方油来改善离子液体在润滑油中的溶解性的方法，其中该配方油包括润滑油基础油作为主要成分，以及离子液体烷基铵盐共基础油或离子液体咪唑盐共基础油作为次要成分。
• 一种用于液封的锌基咪唑类离子液体及其制备方法
  申请人：林州市科能材料科技有限公司

  公开号：CN106478512A

  公开（公告）日：2017-03-08

  一种用于液封的锌基咪唑类离子液体，可根据所需液封具体密度要求或材料要求，选择合适的中间体与锌盐，然后根据所需液封介质具体密度、中间体与锌盐密度，计算所需中间体与锌盐配比，制备得到用于液封的离子液体，其具有以下有益效果：不挥发、不可燃、无燃烧爆炸危险，具有较高的安全性能；液程范围宽，0‑250℃适用；且具有物理和化学稳定性，与多种材料均具有相溶性，且可以通过设计和合成新型离子液体来使其具有更广阔的应用面；本发明的离子液体密度均≥1.2g/ml，较普通介质密度增大，可适用于多种特殊场合，且通过设计合成，可改变离子液体密度，在1.2‑2.0 g/ml范围可调；均相物质，不存在悬浮颗粒问题。