1,2-dimethyl-3-hexadecylimidazolium bromide | 61546-11-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1,2-dimethyl-3-hexadecylimidazolium bromide
• 英文别名: 1-hexadecyl-2,3-dimethylimidazol-1-ium bromide；1-hexadecyl-2,3-dimethylimidazolium bromide；1-Hexadecyl-2,3-dimethyl imidazolium bromide；1-hexadecyl-2,3-dimethylimidazol-3-ium;bromide
• CAS: 61546-11-0
• 化学式: Br*C₂₁H₄₁N₂
• 分子量: 401.474
• InChiKey: AZGTVAPITGDMIN-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  3.11
• 重原子数：
  24
• 可旋转键数：
  15
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  8.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,2-dimethyl-3-hexadecylimidazolium bromide 、 ampicillin sodium salt 以 氯仿 、 水 为溶剂， 反应 48.0h， 以94%的产率得到1-hexadecyl-2,3-dimethylimidazolium ampicillin
  参考文献：
  名称：

  Design, Synthesis, and Biological Evaluation of β-Lactam Antibiotic-Based Imidazolium- and Pyridinium-Type Ionic Liquids

  摘要：

  We herein report the preparation and investigation of antibacterial activity of biocidal ionic liquids (ILs) consisting of cationic imidazolium or pyridinium and an anionic β‐lactam antibiotic. The antibacterial properties were quantified by measuring the minimum inhibitory concentration and minimum bactericidal concentration againstEscherichia coli O157:H7,Klebsiella pneumoniae,Staphylococcus aureus, andEnterococcus faecium. In general, the ILs had improved antibacterial activity than their parent materials, whether individually or in combination. In 83% of the experiments, the ampicillin ILs (Amp‐ILs) had better antibacterial activities than their quaternary halide parent materials, whereas in 92% of the experiments, Amp‐ILs outperformed the commercially available sodium ampicillin salt. Amp‐ILs had up to 43 times improved antibacterial activity than sodium ampicillin. Overall, when normalized for ampicillin content, ILs had greater antimicrobial activity againstE. coli O157:H7,K. pneumoniae,S. aureus, andE. faeciumthan sodium ampicillin alone.

  DOI：

  10.1111/j.1747-0285.2011.01114.x
• 作为产物：
  描述：

  1,2-二甲基咪唑 、 溴代十六烷 以 乙腈 为溶剂， 反应 24.0h， 生成 1,2-dimethyl-3-hexadecylimidazolium bromide
  参考文献：
  名称：

  Synthesis, characterization, and tuning of the liquid crystal properties of ionic materials based on the cyclic polyoxothiometalate [{Mo₄O₄S₄(H₂O)₃(OH)₂}₂(P₈W₄₈O₁₈₄)]³⁶⁻

  摘要：

  聚氧化金属簇与有机阳离子之间的离子相互作用导致离子液晶的形成。

  DOI：

  10.1039/c4sm02551b

文献信息

• Bridging the crystal and solution structure of a series of lipid-inspired ionic liquids
  作者：Sophia A. Bellia、Matthew Metzler、Marissa Huynh、Matthias Zeller、Arsalan Mirjafari、Pamela Cohn、Patrick C. Hillesheim

  DOI：10.1039/d2sm01478e

  日期：——

  interactions and geometries in the solid state, helping to reveal characteristic structural fingerprints for the compounds. The solid-state structures of the ionic liquids are correlated with the solution-state structures through UV-vis spectroscopic studies, further emphasizing the importance of the π interactions in the formation of aggregates. Finally, we investigated the thermal properties of the ionic liquids

  通过X 射线晶体学对一系列带有十六烷基烷基链的 1,2-二甲基咪唑离子液体进行了彻底检查。晶体结构揭示了类脂盐中非共价相互作用的几个关键变化。具体来说，当比较溴化物和碘化物结构时，观察到明显的阳离子-阳离子 π 相互作用。将阴离子变为双（三氟甲烷）磺酰亚胺（Tf 2 N -) 用阴离子⋯π 相互作用改变了这些阳离子-阳离子 π 相互作用。此外，根据烷基链的扭转角和核心平面角，注意到阳离子的几个明确定义的几何形状。Hirshfeld 表面分析用于区分固态中的相互作用和几何形状，有助于揭示化合物的特征结构指纹。通过紫外-可见光谱研究将离子液体的固态结构与溶液态结构相关联，进一步强调了 π 相互作用在聚集体形成中的重要性。最后，我们研究了离子液体的热特性，揭示了含碘物质的复杂相变。这些相变通过以下方式进一步合理化分析从其他结晶盐的结构中收集的数据。
• Polymer exfoliated phyllosilicate nanocomposite compositions and a process for the preparation thereof
  申请人：COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH

  公开号：EP1818360A1

  公开（公告）日：2007-08-15

  The present invention provides a polymer-phyllosilicate nanocomposite composition comprising (a) 10-99.95 % by weight of a matrix polymer and (b) 0.05-90% by weight of a phyllosilicate selected from the group consisting of hydrophilic synthetic phyllosilicates and natural phyllosilicates intercalated with a modifier, an alkylonium ion having reactive moiety. The phyllosilicate is substantially homogeneously dispersed and/or exfoliated throughout the polymer matrix as nanosized particles and the alkylonium ion is substantially covalently linked to the matrix polymer chains. The present invention further provides a process for the preparation of polymer-phyllosilicate nanocomposite.

  本发明提供了一种聚合物-植物硅酸盐纳米复合材料组合物，该组合物包含(a) 10-99.95%（按重量计）的基体聚合物和(b) 0.05-90%（按重量计）的植物硅酸盐，该植物硅酸盐选自由亲水性合成植物硅酸盐和天然植物硅酸盐组成的组，其间插有改性剂，即具有活性分子的烷铵离子。植硅体以纳米级颗粒的形式均匀地分散和/或剥离在聚合物基体中，烷铵离子与基体聚合物链基本上共价连接。本发明进一步提供了一种制备聚合物-植物硅酸盐纳米复合材料的工艺。
• Polymer nanocomposites and methods for their preparation
  申请人：Gupta Deval

  公开号：US20050137310A1

  公开（公告）日：2005-06-23

  Polymer nanocomposites comprising an untreated phyllosilicate, a delaminating agent, a swelling agent, and a polyorganosiloxane-polycarbonate copolymer are disclosed. The polymer nanocomposites are valuable for producing articles having a combination of improved performance characteristics, such as tensile modulus, low temperature ductility, and melt volume rate.

  本发明公开了一种聚合物纳米复合材料，该复合材料由未经处理的硅酸酯、分层剂、膨胀剂和聚有机硅氧烷-聚碳酸酯共聚物组成。这种聚合物纳米复合材料可用于生产具有多种改进性能特征的物品，如拉伸模量、低温延展性和熔体体积率。
• Synthesis of imidazolium and pyridinium-based ionic liquids and application of 1-alkyl-3-methylimidazolium salts as pre-catalysts for the benzoin condensation using solvent-free and microwave activation
  作者：Audrey Aupoix、Bruce Pégot、Giang Vo-Thanh

  DOI：10.1016/j.tet.2009.11.110

  日期：2010.2

  An efficient one-pot procedure for the synthesis of ionic liquids based on nitrogen-containing heterocycles, imidazolium or pyridinium under 'green chemistry' conditions has been described Imidazolium salts and DBU have been found to catalyze efficiently the berizoin condensation giving good yields within very short reaction time using solvent-free microwave activation conditions (C) 2009 Elsevier Ltd All rights reserved
• POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP1697465A2

  公开（公告）日：2006-09-06