N-(3-Chlorosulfonyl-4-methoxyphenyl)maleimide | 152904-01-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯啉
• 英文名称: N-(3-Chlorosulfonyl-4-methoxyphenyl)maleimide
• 英文别名: 5-(2,5-Dioxopyrrol-1-yl)-2-methoxybenzenesulfonyl chloride
• CAS: 152904-01-3
• 化学式: C₁₁H₈ClNO₅S
• 分子量: 301.707
• InChiKey: QVQSXHQWXSPDIP-UHFFFAOYSA-N

物化性质

• 沸点：
  491.2±40.0 °C(Predicted)
• 密度：
  1.580±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  89.1
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  N-(3-Chlorosulfonyl-4-methoxyphenyl)maleimide 以 乙腈 为溶剂， 生成
  参考文献：
  名称：

  CHLOROSULFONATION OFN-ARYLMALEIMIDES

  摘要：

  N-phenylmaleimides, o-, m- and p- substituted (1) reacted with excess chlorosulfonic acid to give the corresponding sulphonyl chlorides (2-5). These were condensed with amines and phenols to give derivatives (7-29) which underwent hydrolysis or ammonolysis to give respectively the sulfamoyl maleamic acids (31-34) and sulfamoyl maleamides (35-39).

  DOI：

  10.1080/10426509308034412
• 作为产物：
  描述：

  甲氧苯胺 在 氯磺酸 、 sodium acetate 、 乙酸酐 作用下， 以 乙醚 、 氯仿 为溶剂， 反应 3.5h， 生成 N-(3-Chlorosulfonyl-4-methoxyphenyl)maleimide
  参考文献：
  名称：

  CHLOROSULFONATION OFN-ARYLMALEIMIDES

  摘要：

  N-phenylmaleimides, o-, m- and p- substituted (1) reacted with excess chlorosulfonic acid to give the corresponding sulphonyl chlorides (2-5). These were condensed with amines and phenols to give derivatives (7-29) which underwent hydrolysis or ammonolysis to give respectively the sulfamoyl maleamic acids (31-34) and sulfamoyl maleamides (35-39).

  DOI：

  10.1080/10426509308034412

文献信息

• Tome, Augusto C.; Cavaleiro, Jose A. S.; Domingues, Fernando M. J., Phosphorus, Sulfur and Silicon and the Related Elements, 1993, vol. 79, # 1,4, p. 187 - 194
  作者：Tome, Augusto C.、Cavaleiro, Jose A. S.、Domingues, Fernando M. J.、Cremlyn, Richard J.

  DOI：——

  日期：——
• CHLOROSULFONATION OF<i>N</i>-ARYLMALEIMIDES
  作者：Augusto C. Tomé、José A. S. Cavaleiro、Fernando M. J. Domingues、Richard J. Cremlyn

  DOI：10.1080/10426509308034412

  日期：1993.6

  N-phenylmaleimides, o-, m- and p- substituted (1) reacted with excess chlorosulfonic acid to give the corresponding sulphonyl chlorides (2-5). These were condensed with amines and phenols to give derivatives (7-29) which underwent hydrolysis or ammonolysis to give respectively the sulfamoyl maleamic acids (31-34) and sulfamoyl maleamides (35-39).