L-7202

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: L-7202
• 英文别名: N-[(2S)-1-[[(4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]amino]-1-oxopropan-2-yl]-2-hydroxybenzamide
• 化学式: C₁₈H₂₄N₂O₈
• 分子量: 396.397
• InChiKey: SONKDSVDJMOIRF-DEKNXZFASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  147
• 氢给体数：
  5
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  4,6-O-ethylidene-β-D-glucopyranosylamine 在 哌啶 、 氯甲酸乙酯 、 1-羟基苯并三唑 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 、 三乙胺 作用下， 以 1,4-二氧六环 、 N,N-二甲基甲酰胺 为溶剂， 反应 15.5h， 生成 L-7202
  参考文献：
  名称：

  Synthesis of cupric acetate selective receptor derived from alanyl glycoconjugate and their application in selective oxidation of benzylic alcohols

  摘要：

  Cupric acetate sensing ability of alanyl-(4,6-O-ethylidene-beta-O-glucopyranosylamine) derived receptor (L-N2O2) has been explored using fluorescence and UV-visible absorption spectroscopy. Cupric acetate quenches the fluorescence intensity of L-N2O2 with a correlation coefficient, R=0.978 and Stern Volmer constant, K-SV = 38,067 M-1 revealing the possibilities of interaction via dynamic mode. Further, copper complex of L-N2O2 has been utilized in selective oxidation of primary and secondary alcohols into the corresponding carbonyl compounds. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.catcom.2012.08.024
• 作为试剂：
  描述：

  1-(4-氯苯基)乙醇 在 2,2,6,6-四甲基哌啶氧化物 、 L-7202 、 copper diacetate 、 1-butyl-3-methylimidazolium Tetrafluoroborate 作用下， 反应 6.0h， 以68%的产率得到对氯苯乙酮
  参考文献：
  名称：

  Synthesis of cupric acetate selective receptor derived from alanyl glycoconjugate and their application in selective oxidation of benzylic alcohols

  摘要：

  Cupric acetate sensing ability of alanyl-(4,6-O-ethylidene-beta-O-glucopyranosylamine) derived receptor (L-N2O2) has been explored using fluorescence and UV-visible absorption spectroscopy. Cupric acetate quenches the fluorescence intensity of L-N2O2 with a correlation coefficient, R=0.978 and Stern Volmer constant, K-SV = 38,067 M-1 revealing the possibilities of interaction via dynamic mode. Further, copper complex of L-N2O2 has been utilized in selective oxidation of primary and secondary alcohols into the corresponding carbonyl compounds. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.catcom.2012.08.024

文献信息

• Synthesis of cupric acetate selective receptor derived from alanyl glycoconjugate and their application in selective oxidation of benzylic alcohols
  作者：Ajay K. Sah、Kiran Soni

  DOI：10.1016/j.catcom.2012.08.024

  日期：2012.11

  Cupric acetate sensing ability of alanyl-(4,6-O-ethylidene-beta-O-glucopyranosylamine) derived receptor (L-N2O2) has been explored using fluorescence and UV-visible absorption spectroscopy. Cupric acetate quenches the fluorescence intensity of L-N2O2 with a correlation coefficient, R=0.978 and Stern Volmer constant, K-SV = 38,067 M-1 revealing the possibilities of interaction via dynamic mode. Further, copper complex of L-N2O2 has been utilized in selective oxidation of primary and secondary alcohols into the corresponding carbonyl compounds. (C) 2012 Elsevier B.V. All rights reserved.