cytidine guanosine base pair

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷
• 英文名称: cytidine guanosine base pair
• 英文别名: CG Watson-Crick base pair；rCyd.rGuo；2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one;4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
• 化学式: C₉H₁₃N₃O₅*C₁₀H₁₃N₅O₅
• 分子量: 526.463
• InChiKey: RWBNMHKFKUFMLK-FBGCOTALSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.25
• 重原子数：
  37
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  284
• 氢给体数：
  9
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  cytidine guanosine base pair 以 甲醇 、 二甲基亚砜 为溶剂， 生成 鸟苷 、 胞苷
  参考文献：
  名称：

  Watson-Crick base pairing between guanosine and cytidine studied by carbon-13 nuclear magnetic resonance spectroscopy

  摘要：

  DOI：

  10.1021/ja00408a006
• 作为产物：
  描述：

  鸟苷 、 胞苷 以 甲醇 、 二甲基亚砜 为溶剂， 生成 cytidine guanosine base pair
  参考文献：
  名称：

  Watson-Crick base pairing between guanosine and cytidine studied by carbon-13 nuclear magnetic resonance spectroscopy

  摘要：

  DOI：

  10.1021/ja00408a006

文献信息

• Detectably labeled dual conformation oligonucleotide Probes, Assays and Kits
  申请人：THE PUBLIC HEALTH RESEARCH INSTITUTE OF THE CITY OF NEW YORK, INC.

  公开号：EP0745690A2

  公开（公告）日：1996-12-04

  Unimolecular and bimolecular hybridization probes for the detection of nucleic acid target sequences comprise a target complement sequence, an affinity pair holding the probe in a closed conformation in the absence of target sequence, and either a label pair that interacts when the probe is in the closed conformation or, for certain unimolecular probes, a non-interactive label. Hybridization of the target and target complement sequences shifts the probe to an open conformation. The shift is detectable due to reduced interaction of the label pair or by detecting a signal from a non-interactive label. Certain unimolecular probes can discriminate between target and non-target sequences differing by as little as one nucleotide. Also, universal stems and kits useful for constructing said probes. Also, assays utilizing said probes and kits for performing such assays. Also, such probes capable of allelic discrimination.

  用于检测核酸目标序列的单分子和双分子杂交探针包括目标互补序列、在没有目标序列的情况下保持探针封闭构象的亲和对、以及当探针处于封闭构象时发生相互作用的标签对，或者对于某些单分子探针来说，非互作性标签。目标序列和目标互补序列的杂交会使探针转变为开放构象。由于标签对的相互作用减弱，或通过检测非互作标签的信号，可检测到这种转变。某些单分子探针可以区分差异仅为一个核苷酸的目标和非目标序列。此外，还有用于构建所述探针的通用茎和试剂盒。还有，利用所述探针和试剂盒进行的测定。还有，能够区分等位基因的探针。
• Detectably labeled dual conformation oligonucleotide probes, assays and kits
  申请人：PHRI Properties, Inc.

  公开号：EP2053134A2

  公开（公告）日：2009-04-29

  Unimolecular and bimolecular hybridization probes for the detection of nucleic acid target sequences comprise a target complement sequence, an affinity pair holding the probe in a closed conformation in the absence of target sequence, and either a label pair that interacts when the probe is in the closed conformation or, for certain unimolecular probes, a non-interactive label. Hybridization of the target and target complement sequences shifts the probe to an open conformation. The shift is detectable due to reduced interaction of the label pair or by detecting a signal from a non-interactive label. Certain unimolecular probes can discriminate between target and non-target sequences differing by as little as one nucleotide. Also, universal stems and kits useful for constructing said probes. Also, assays utilizing said probes and kits for performing such assays. Also, such probes capable of allelic discrimination.

  用于检测核酸目标序列的单分子和双分子杂交探针包括目标互补序列、在没有目标序列的情况下保持探针封闭构象的亲和对、以及当探针处于封闭构象时发生相互作用的标签对，或者对于某些单分子探针来说，非互作性标签。目标序列和目标互补序列的杂交会使探针转变为开放构象。由于标签对的相互作用减弱，或通过检测非互作标签的信号，可检测到这种转变。某些单分子探针可以区分差异仅为一个核苷酸的目标和非目标序列。此外，还有用于构建所述探针的通用茎和试剂盒。还有，利用所述探针和试剂盒进行的测定。还有，能够区分等位基因的探针。
• Novel glucose oxidase variants
  申请人：Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.

  公开号：EP2796547A1

  公开（公告）日：2014-10-29

  The technology provided herein relates to novel variants of microbial glucose oxidase with improved properties, more specifically to polypeptides having glucose oxidase activity as their major enzymatic activity; to nucleic acid molecules encoding said glucose oxidases; vectors and host cells containing the nucleic acids and methods for producing the glucose oxidase; compositions comprising said glucose oxidase; methods for the preparation and production of such enzymes; and to methods for using such enzymes for food and feed processing, for the measurement of free glucose in clinical samples and bioreactors, and the development of miniature biofuel cells.

  本文提供的技术涉及具有改进特性的微生物葡萄糖氧化酶的新型变体，更具体地说， 涉及以葡萄糖氧化酶活性为其主要酶活性的多肽；涉及编码所述葡萄糖氧化酶的核酸分子； 涉及含有所述核酸的载体和宿主细胞以及生产葡萄糖氧化酶的方法；包含所述葡萄糖氧化酶的组合物；制备和生产这种酶的方法；以及将这种酶用于食品和饲料加工、测量临床样品和生物反应器中的游离葡萄糖以及开发微型生物燃料电池的方法。
• Novel pest control methods
  申请人：Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.

  公开号：EP2810952A1

  公开（公告）日：2014-12-10

  The technology provided herein relates to methods of insect pest control by incorporating an inhibitor against the structural sheath protein (SHP) into the body of an agricultural target pest, and to pest control agents to be used in the method and to transgenic crop, greenhouse and ornamental plants.

  本文提供的技术涉及通过在农业目标害虫体内加入针对结构鞘蛋白（SHP）的抑制剂来控制害虫的方法，以及用于该方法的害虫控制剂和转基因作物、温室和观赏植物。
• METHODS OF MULTI-SPECIES INSECT PEST CONTROL
  申请人：FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V.

  公开号：EP3825408A1

  公开（公告）日：2021-05-26

  The technology provided herein relates to compounds and methods of multi-species insect pest control by incorporating an inhibitor against a histone acetyltransferase (HAT) into the body of an agricultural target pest, and to pest control agents to be used in the method and to transgenic crop, greenhouse and ornamental plants.

  本文提供的技术涉及通过在农业目标害虫体内加入组蛋白乙酰转移酶（HAT）抑制剂来控制多物种昆虫害虫的化合物和方法，以及用于该方法的害虫控制剂和转基因作物、温室和观赏植物。