作者:Michael E. Jung、Daniel L. Sun
DOI:10.1016/j.tetlet.2014.11.103
日期:2015.6
The intermediate epoxy alcohols prepared via a Payne rearrangement can be trapped with arylselenide anions, giving mixtures of ring-opened products. The 1-arylseleno-2,3-diols are generally favored over the 3-arylseleno-1,2-diols in this process although the reaction of trisubstituted epoxyalcohols, for example, 17, differs from those of disubstituted epoxyalcohols, for example, 21.
通过Payne重排制备的中间体环氧醇可被芳硒化物阴离子捕获,得到开环产物的混合物。尽管三取代环氧醇(例如17)的反应不同于二取代环氧醇(例如21)的反应,但是在此方法中,1-芳基硒代2,3-二醇通常比3-芳基硒代1,2-二醇更受青睐。。