γ-hexanolactone | 15964-17-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: γ-hexanolactone
• 英文别名: 4-propyloxetan-2-one
• CAS: 15964-17-7
• 化学式: C₆H₁₀O₂
• 分子量: 114.144
• InChiKey: VLGDSNWNOFYURG-UHFFFAOYSA-N

物化性质

• 沸点：
  173.0±9.0 °C(Predicted)
• 密度：
  1.013±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  γ-hexanolactone 生成 3-hydroxy-N-phenylhexanamide
  参考文献：
  名称：

  Production of beta-hydroxy carboxylic acid lactones from ketene and aldehyde with clay catalyst

  摘要：

  公开号：

  US02580714A1
• 作为产物：
  描述：

  3-羟基己酸 在 2,2'-二硫二吡啶 、 三苯基膦 、 mercuric triflate 作用下， 以 二氯甲烷 、 乙腈 为溶剂， 反应 0.83h， 以42%的产率得到γ-hexanolactone
  参考文献：
  名称：

  长链β-内酯的合成及其对致病性分枝杆菌的抗菌活性。

  摘要：

  为了寻求新的抗菌剂，开发了一系列新颖的长链和中链单和双取代β-内酯。它们针对三种致病性分枝杆菌-M的活性。通过刃天青素微量滴定分析（REMA）评估脓肿，海藻分枝杆菌和结核分枝杆菌。在合成的16种β-内酯中，只有3-十六烷基氧杂环丁烷-2-酮（VM005）表现出对脓肿分支杆菌的有希望的活性，而大多数β-内酯表现出了有趣的抗海藻分支杆菌的活性，类似于经典抗生素，异烟肼。关于结核分枝杆菌，发现有六种化合物对这种分枝杆菌有活性，与β-内酯VM008 [反式-（Z）-3-（十六烷基-7-烯-1-基）-4-丙基氧杂环丁烷-2-一]是最好的生长抑制剂。

  DOI：

  10.1002/cmdc.201800720

文献信息

• Method for Producing Polyhydroxyalkanoates
  申请人：Preishuber-Pflugl Peter

  公开号：US20090124787A1

  公开（公告）日：2009-05-14

  The invention relates to a process for preparing polyhydroxyalkanoates by polymerization of lactones of the general formula I, where the substituents and the index n have the meanings given in the description, in the presence of at least one catalyst of the formula (II) L I M a X a m , where the substituents and indices have the meanings given in the description. The invention further relates to poly-3-hydroxybutyrates which have a novel property profile and are obtainable for the first time by means of this process, and also biodegradable polyester mixtures based on these poly-3-hydroxybutyrates.

  本发明涉及一种通过在至少一种催化剂的存在下，聚合通式I的内酯制备聚羟基烷酸酯的方法，其中通式I的取代基和指数n的含义在说明中给出，催化剂的通式为(II) LIMaXam，其中取代基和指数的含义在说明中给出。本发明还涉及具有新的性质特征的聚-3-羟基丁酸酯，首次通过该方法获得，并且基于这些聚-3-羟基丁酸酯的可生物降解聚酯混合物。
• PROCESS FOR PRODUCING B-BUTYROLACTONE HOMOPOLYMER OR COPOLYMER
  申请人：——

  公开号：US20020052458A1

  公开（公告）日：2002-05-02

  The object of the invention is to provides a process in which a high-molecular-weight &bgr;-butyrolactone homopolymer or copolymer being biodegradable, absorbable into the living body, useful as a functional polymeric material and superior in physical characteristics is produced with high yield and good productivity. This object is solved by a process for producing the homopolymer or copolymer of the invention, which comprises ring-opening polymerization of sole &bgr;-butyrolactone subjected previously to acid removal and dehydration treatment, or of said &bgr;-butyrolactone with other lactones, in the presence of a tin compound represented by the following formula (1) and/or formula (2): 1 wherein R 1 and R 2 and R 4 to R 7 independently represent an alkyl group containing 1 to 12 carbon atoms which may have a branched chain, or a cycloalkyl group containing 5 to 7 carbon atoms, or a phenyl or naphthyl group which may have a substituent group, R 3 represents an alkylene group containing 2 to 12 carbon atoms which may have a substituent group, a cyclopentane-1,2-ylene group or a cyclohexane-1,2-ylene group, and n is an integer of 1 to 10.

  本发明的目的是提供一种高分子量的β-丁内酯均聚物或共聚物的制备方法，该聚物具有生物降解性，可吸收进入生物体内，可用作功能性聚合物材料，并且物理特性优良，且产量高且生产效率好。本发明的目的通过以下制备该发明的均聚物或共聚物的方法来解决：在预先去除酸和脱水处理的单一β-丁内酯或与其他内酯混合的β-丁内酯存在下，进行开环聚合反应，反应中存在以下式（1）和/或式（2）所表示的锡化合物：其中R1、R2和R4到R7独立地表示含1至12个碳原子的烷基，可以是支链的，或者含5至7个碳原子的环烷基，或者含有取代基的苯基或萘基，R3表示含有2至12个碳原子的烷基，可以是含有取代基的环戊-1,2-亚基或环己-1,2-亚基，n为1至10的整数。
• Resin composition
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0368283A2

  公开（公告）日：1990-05-16

  A resin composition which is excellent in balance of mechanical properties and processability, solvent resistance and chemical resistance comprising: (a) a polyphenylene ether resin, (b) a thermoplastic polyester resin, and (c) a compound represented by the formula:         (HO)mmR²(COOR²)n wherein R¹ represents a straight or branched chain saturated aliphatic hydrocarbon group of 2-20 carbon atoms, R² represents a hydrogen atom or an alkyl or aryl group of 1-20 carbon atoms and R¹ and R² may be identical or different and m and n each represents an integer of 1 or more or a derivative thereof. This composition may further contain a rubber-like polymer.

  一种在机械性能、加工性能、耐溶剂性和耐化学性之间具有良好平衡的树脂组合物，包括 (a) 聚苯醚树脂、 (b) 热塑性聚酯树脂，和 (c) 一种由式表示的化合物： (HO)mmR²(COOR²)n 其中 R¹ 代表 2-20 个碳原子的直链或支链饱和脂肪烃基，R² 代表氢原子或 1-20 个碳原子的烷基或芳基，R¹ 和 R² 可以相同或不同，m 和 n 各代表 1 个或更多的整数或其衍生物。 该组合物还可含有一种橡胶状聚合物。
• Thermoplastic resin composition and article comprising the same
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0456259A1

  公开（公告）日：1991-11-13

  A thermoplastic resin composition containing a polyamide resin composition (C) consisting of a polyamide resin (A) and another thermoplastic resin (B) and at least one modifier (D) is excellent in coatability, mechanical properties, linear expansion coefficient and appearance, can be molded into an article which comprises the polyamide resin (C), wherein the ratio of the percent occupied area of the polyamide resin on the surface of the article to the weight percentage of the polyamide in the polyamide resin composition (C) is not less than l.2, and/or the ratio of the percent concentration of the polyamide resin on the surface of the article determined on the basis of the nitrogen concentration on the surface of the article to the weight percentage of the polyamide in the polyamide resin composition (C) is not less than l,2, which article is suited for electric and electronic parts and automobile parts such as a bumper, fender and wheel cover.

  一种含有聚酰胺树脂组合物(C)的热塑性树脂组合物，该组合物由聚酰胺树脂(A)和另一种热塑性树脂(B)以及至少一种改性剂(D)组成，具有优异的涂覆性、机械性能、线膨胀系数和外观，可以模塑成包含聚酰胺树脂(C)的制品，其中制品表面聚酰胺树脂所占面积百分比与聚酰胺树脂组合物(C)中聚酰胺的重量百分比之比不小于 l.2、和/或根据物品表面氮浓度确定的物品表面聚酰胺树脂浓度百分比与聚酰胺树脂组合物(C)中聚酰胺重量百分比之比不小于l,2，该物品适用于电气和电子零件以及汽车零件，如保险杠、挡泥板和车轮罩。
• Biodegradable copolymers and plastic articles comprising biodegradable copolymers of 3-Hydroxyhexanoate.
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP1375556A2

  公开（公告）日：2004-01-02

  The present invention relates to biodegradable PHA copolymers comprising at least two randomly repeating monomer units (RRMU) wherein the first RRMU has structure (I) wherein R1 is H or C2 alkyl, and n is 1 or 2; the second RRMU has structure (II); and wherein at least 50 % of the RRMU have the structure of the first RRMU. The present invention further relates to plastic articles comprising said biodegradable PHA copolymers. The present invention further relates to an absorbent article comprising a liquid pervious topsheet, a liquid impervious backsheet comprising a film comprising a PHA of the present invention and an absorbent core positioned between the topsheet and the backsheet.

  本发明涉及由至少两个无规重复单体单元（RRMU）组成的可生物降解的PHA共聚物，其中第一个RRMU具有结构(I)，其中R1是H或C2烷基，n是1或2；第二个RRMU具有结构(II)；并且至少50%的RRMU具有第一个RRMU的结构。 本发明还涉及包含所述可生物降解 PHA 共聚物的塑料制品。 本发明还涉及一种吸收制品，包括透液表层、不透液背层（由本发明 PHA 组成的薄膜构成）以及位于表层和背层之间的吸收芯。