D-galactose 4-sulphate | 13077-95-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: D-galactose 4-sulphate
• 英文别名: D-galactose-4-O-sulphate；Gal-S；O⁴-Sulfo-D-galactose；d-Galactose-4-sulfate；[(2R,3S,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl] hydrogen sulfate
• CAS: 13077-95-7
• 化学式: C₆H₁₂O₉S
• 分子量: 260.222
• InChiKey: ACRPXCXKILJIJN-KCDKBNATSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.8
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  170
• 氢给体数：
  5
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  D-galactose 4-sulphate 在 盐酸 作用下， 以 水 为溶剂， 生成 口服葡萄糖
  参考文献：
  名称：

  On the desulphation of carbohydrate sulphates

  摘要：

  DOI：

  10.1016/0008-6215(83)88470-5
• 作为产物：
  描述：

  methyl D-galactose-4-O-sulphate 在 trityl tetrafluoroborate 作用下， 以 二氯甲烷 为溶剂， 生成 D-galactose 4-sulphate
  参考文献：
  名称：

  [EN] COMPOSITION COMPRISING SULPHATED GALACTOSE, AND IMPLEMENTATIONS THEREOF
  [FR] COMPOSITION COMPRENANT DU GALACTOSE SULFATÉ ET SES MODES DE RÉALISATION

  摘要：

  本公开披露了一种组合物，包括：（a）至少一种硫酸化半乳糖；和（b）至少一种从双糖、三糖、四糖、五糖和其盐组成的群体中选择的低聚糖。本公开披露进一步披露了至少一种硫酸化半乳糖的重量百分比在总糖含量的15-90％范围内。此外，本公开披露了将该组合物用于保护/治疗植物免受感染的用途。还提供了将该组合物用于保护/治疗动物免受感染的用途。本公开披露了将硫酸化半乳糖用于保护/治疗植物免受感染的用途。还提供了将硫酸化半乳糖用于保护/治疗动物免受感染的用途。本公开披露还披露了制备上述组合物的方法。

  公开号：

  WO2020095329A1

文献信息

• Low-emulsifier or emulsifier-free systems of the oil-in-water type with a content of stabilizers and an amino-substituted hydroxybenzophenone
  申请人：——

  公开号：US20030124158A1

  公开（公告）日：2003-07-03

  Cosmetic or dermatological preparations which represent finely disperse systems of the oil-in-water type, comprising a) an oil phase, b) a water phase, c) one or more stabilizers, d) at most 2.00% by weight of one or more emulsifiers, and e) an amino-substituted hydroxybenzophenone of the formula I 1

  化妆品或皮肤科制剂，代表油包水型的细分散系统，包括 a) 油相， b) 水相， c) 一种或多种稳定剂， d) 最多占总重量的2.00%的一种或多种乳化剂，以及 e) 公式I的氨基取代羟基苯酮 1
• Use of multivalent glycodendrimers to inhibit the activity of human immunodeficiency virus
  申请人：——

  公开号：US20040180852A1

  公开（公告）日：2004-09-16

  The present invention relates to compositions and methods for inhibiting the interaction of a ligand and receptor. In particular, compositions are methods are provided for inhibition of interaction between a virus, especially HIV, and a receptor. Inhibition of such ligand/receptor interaction is advantageous in inhibiting infection of a cell with a virus. Further, an inhibitor of ligand/receptor interaction serves as a standard in assays of inhibition in vitro or in vivo. In a particular embodiment, a composition according to the invention includes a compound having the formula: [(X)—(Y)] p -Z where X is 1 and where Q1 and Q2 are each independently H, a bond to Y, or a bond to Z, where at least one of Q1 or Q2 is a bond to Y or a bond to Z; where R1, R4, R6 and R8 are each H; R2, R3, and R5 are each independently OH, OSO3D, or OPO3D, and R7 is CH20H, CH2OSO3D or CH2OPO3D; where D is H or a cation selected from the group consisting of: alkali metal cations, alkaline earth metal cations, ammonium cations, quaternary ammonium cations and amine cations; and where at least one of R2, R3, R5 and R7 is a sulfur or phosphate containing group; where Y is an optional linker, Z is a multivalent support, and p is an integer in the range of 1-2000 inclusive.

  本发明涉及用于抑制配体和受体相互作用的组合物和方法。具体而言，提供了用于抑制病毒（特别是HIV）与受体之间相互作用的组合物和方法。抑制此类配体/受体相互作用有助于抑制细胞感染病毒。此外，配体/受体相互作用的抑制剂可作为体外或体内抑制测定的标准。在一个特定实施例中，根据本发明的组合物包括具有以下结构的化合物：[(X)—(Y)] p -Z，其中X为1，Q1和Q2分别独立地为H、与Y的键或与Z的键，其中Q1或Q2中至少有一个是与Y的键或与Z的键；R1、R4、R6和R8各自为H；R2、R3和R5各自独立地为OH、OSO3D或OPO3D，R7为CH20H、CH2OSO3D或CH2OPO3D；D为H或从以下群组中选择的阳离子：碱金属阳离子、碱土金属阳离子、铵阳离子、季铵阳离子和胺阳离子；其中R2、R3、R5和R7中至少有一个是含硫或磷酸酯基团；Y为可选的连接剂，Z为多价支持体，p为在1-2000范围内的整数。
• Dishwasher agent with additional uses
  申请人：——

  公开号：US20040106534A1

  公开（公告）日：2004-06-03

  The invention relates to a cleaning agent for dishwashers comprising a first part (basic composition), which mainly acts during the main cleaning cycle of the dishwasher, and a second part, which mainly acts during the rinsing cycle of the dishwasher as a result a suitable coating. The second part contains one or several substances form the following group: detergency builders, acidifying agents, chelate complex builders or coating inhibiting polymers.

  该发明涉及一种用于洗碗机的清洁剂，包括第一部分（基础组成部分），主要在洗碗机的主要清洗循环期间起作用，以及第二部分，主要在洗碗机的冲洗循环期间作为适当的涂层起作用。第二部分包含以下组合中的一种或多种物质：清洁剂、酸化剂、螯合剂或涂层抑制聚合物。
• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Polymeric Coatings Incorporating Bioactive Enzymes for Catalytic Function
  申请人：McDaniel C. Steven

  公开号：US20120097194A1

  公开（公告）日：2012-04-26

  Disclosed herein are materials including a polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a coating, a textile finish or a wax; a filler for such a polymeric material or a surface treatment, which includes an enzyme such as an esterase (e.g., a lipolytic enzyme, an organophosphorus compound degradation enzyme), wherein the enzyme decontaminates a chemical from the surface of the material. Also disclosed herein are methods of cleaning a surface of a material that comprises an enzyme.

  本文公开了一种材料，包括聚合物材料，例如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；表面处理，例如涂层、纺织品处理或蜡；用于上述聚合物材料或表面处理的填料，其中包括酶，例如酯酶（例如脂肪水解酶、有机磷化合物降解酶），其中酶可从材料表面去除化学物质。本文还公开了一种清洁含有酶的材料表面的方法。