N4-Benzo(g)quinolin-4-yl-N1-(6-methoxy-8-quinolyl)pentane-1,4-diamine | 127136-59-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N4-Benzo(g)quinolin-4-yl-N1-(6-methoxy-8-quinolyl)pentane-1,4-diamine
• 英文别名: 4-N-benzo[g]quinolin-4-yl-1-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
• CAS: 127136-59-8
• 化学式: C₂₈H₂₈N₄O
• 分子量: 436.5
• InChiKey: MDVIJALEQKTJLR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  33
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  59.1
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• COMPOUNDS FOR TREATING DISEASE, FOR ADMINISTERING, AND FOR PHARMACEUTICAL COMPOSITIONS
  申请人：Trent John O.

  公开号：US20130059852A1

  公开（公告）日：2013-03-07

  Some embodiments of this invention include methods for treating disease and methods for administering a compound of Formula (I). In some aspects of the invention, diseases can be treated by administration of compositions comprising a compound of Formula (I). Pharmaceutical compositions of some embodiments of the present invention comprise a compound of Formula (I).
• US8785490B2
  申请人：——

  公开号：US8785490B2

  公开（公告）日：2014-07-22
• US9145398B2
  申请人：——

  公开号：US9145398B2

  公开（公告）日：2015-09-29
• [EN] COMPOUNDS FOR TREATING DISEASE, FOR ADMINISTERING, AND FOR PHARMACEUTICAL COMPOSITIONS<br/>[FR] COMPOSÉS POUR LE TRAITEMENT D'UNE MALADIE, POUR L'ADMINISTRATION, ET POUR DES COMPOSITIONS PHARMACEUTIQUES
  申请人：UNIV LOUISVILLE RES FOUND

  公开号：WO2011127333A2

  公开（公告）日：2011-10-13

  Some embodiments of this invention include methods for treating disease and methods for administering a compound of Formula (I). In some aspects of the invention, diseases can be treated by administration of compositions comprising a compound of Formula (I). Pharmaceutical compositions of some embodiments of the present invention comprise a compound of Formula (I).