1,1'-diethyl-2,4'-cyanine | 24144-04-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1,1'-diethyl-2,4'-cyanine
• 英文别名: (2Z)-1-ethyl-2-[(1-ethylquinolin-1-ium-4-yl)methylidene]quinoline
• CAS: 24144-04-5
• 化学式: C₂₃H₂₃N₂
• 分子量: 327.449
• InChiKey: CJRNTVYQEXDVCB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  7.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• CYANOBORATE, FLUOROALKYLPHOSPHATE, FLUOROALKYLBORATE OR IMIDE DYES
  申请人：IGNATYEV Nikolai (Mykola)

  公开号：US20110190480A1

  公开（公告）日：2011-08-04

  The present invention relates to dyes of the general formula CAT + Y − (I), where Y − is an anion selected from the group of the cyanoborates, fluoroalkylphosphates, fluoroalkylborates or imidates and CAT + is a cation selected from the group of the azine, xanthene, polymethine, styryl, azo, tetrazolium, pyrylium, benzopyrylium, thiopyrylium, benzothiopyrylium, thiazine, oxazine, triarylmethane, diarylmethane, methine, acridine, quinoline, isoquinoline or quaternary azafluorenone dyes, for colouring plastics and plastic fibres, for the preparation of flexographic printing inks, as ball-point pen pastes, as stamp ink, for colouring leather and paper, for use in data acquisition systems, reprography, in ink microfilters, in photogalvanics, laser technology and the photo industry.

  本发明涉及一般式CAT+Y−（I）的染料，其中Y−是从氰硼酸盐、氟烷基磷酸盐、氟烷基硼酸盐或咪唑盐群中选择的阴离子，CAT+是从偶氮、黄色素、聚甲烯、苯乙烯、偶氮、四唑、吡啶、苯并吡喃、硫吡喃、苯并硫吡喃、噻吩、噁唑、三芳基甲烷、二芳基甲烷、甲烷、吖啶、喹啉、异喹啉或季铵氮芴酮染料群中选择的阳离子，用于着色塑料和塑料纤维，制备柔性版印刷油墨，作为圆珠笔膏、邮票墨水，用于着色皮革和纸张，用于数据采集系统，复印术，墨水微滤器，光电镀技术，激光技术和光学工业。
• REAGENT AND REAGENT KIT FOR ANALYSIS OF PRIMITIVE LEUKOCYTE
  申请人：Sysmex Corporation

  公开号：EP2166354A1

  公开（公告）日：2010-03-24

  The present invention provides a reagent for analysis of immature leukocytes comprising: a surfactant which can damage cell membranes of erythrocytes and mature leukocytes, a solubilizing agent which can shrink the damaged blood cells and at least one dye for staining nucleic acid selected from the dyes of the formulae (I) and (II), wherein X- is an anion.

  本发明提供了一种用于分析未成熟白细胞的试剂，包括 一种表面活性剂，可破坏红细胞和成熟白细胞的细胞膜、 可使受损血细胞缩小的增溶剂，以及 至少一种用于染色核酸的染料，选自式 (I) 和 (II) 染料，其中 X- 是阴离子。
• ANTI-NEURODEGENERATIVE DISEASE AGENT
  申请人：Hayashibara Co., Ltd.

  公开号：EP3858355A1

  公开（公告）日：2021-08-04

  The present invention addresses the problem of providing an orally-administrable anti-neurodegenerative disease agent having an action of accelerating neurocyte growth and an action of promoting neurite-outgrowth, and having excellent transfer properties to central nervous tissues. The problem is solved by providing an anti-neurodegenerative disease agent containing a compound represented by General formula 4 as an active ingredient, and having an action of accelerating neurocyte growth, an action of promoting neurite-outgrowth, and an action of scavenging reactive oxygen species. In General formula 4, R10 and R11 represent the same or different alkyl group having 2-8 carbon atoms, and the alkyl group may be either a straight chain or a branched chain. n represents an integer of 0 or 1, and X4- represents a suitable counter anion that is pharmaceutically acceptable.

  本发明所要解决的问题是提供一种可口服的抗神经退行性疾病药物，该药物具有加速神经细胞生长和促进神经元生长的作用，并且对中枢神经组织具有良好的转移特性。本发明通过提供一种抗神经退行性疾病制剂来解决上述问题，该制剂含有通式 4 所代表的化合物作为活性成分，具有加速神经细胞生长的作用、促进神经元生长的作用以及清除活性氧的作用。通式 4 中，R10 和 R11 代表具有 2-8 个碳原子的相同或不同的烷基，烷基可以是直链或支链，n 代表 0 或 1 的整数，X4- 代表药学上可接受的合适的反阴离子。
• Lithographic printing form precursor and method of producing a lithographic printing form
  申请人：Kodak Polychrome Graphics Company Ltd.

  公开号：EP1289769B1

  公开（公告）日：2012-07-11
• Methods for the Treatment of ADHD and Related Disorders
  申请人：Teicher Martin

  公开号：US20090221552A1

  公开（公告）日：2009-09-03

  The invention features methods, compositions, and kits for the treatment of attention deficit hyperactivity disorder and related behavioral disorders by administering an organic cation 3 (hOCT3) inhibitor.