3-Isobutylamino-5,5-dimethyl-cyclohex-2-enone | 82663-49-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-Isobutylamino-5,5-dimethyl-cyclohex-2-enone
• 英文别名: 5,5-Dimethyl-3-i-butylamino-cyclohex-2-en-1-one；5,5-dimethyl-3-(2-methylpropylamino)cyclohex-2-en-1-one
• CAS: 82663-49-8
• 化学式: C₁₂H₂₁NO
• 分子量: 195.305
• InChiKey: TWJANHDHUVWEPJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  异丁胺 、 5,5-二甲基-1,3-环己二酮 在 silica-supported phosphorous pentoxide 作用下， 反应 0.08h， 以86%的产率得到3-Isobutylamino-5,5-dimethyl-cyclohex-2-enone
  参考文献：
  名称：

  P₂O₅/SiO₂as a New, Efficient, and Reusable Catalyst for Preparation ofβ-Enaminones Under Solvent-Free Conditions

  摘要：

  P2O5/SiO2 (30%w/w) was applied as an efficient, heterogeneous, and reusable catalyst for the synthesis of -enaminones. The reactions were rapidly completed at 80C under solvent-free conditions and products were obtained in good to excellent yields.

  DOI：

  10.1080/00397910802513052

文献信息

• P₂O₅/SiO₂as a New, Efficient, and Reusable Catalyst for Preparation of<font>β</font>-Enaminones Under Solvent-Free Conditions
  作者：Mohammad R. Mohammadizadeh、A. Hasaninejad、M. Bahramzadeh、Z. Sardari Khanjarlou

  DOI：10.1080/00397910802513052

  日期：2009.3.10

  P2O5/SiO2 (30%w/w) was applied as an efficient, heterogeneous, and reusable catalyst for the synthesis of -enaminones. The reactions were rapidly completed at 80C under solvent-free conditions and products were obtained in good to excellent yields.