Einecs 279-164-2 | 79458-68-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Einecs 279-164-2
• 英文别名: (2R)-2-amino-3-(carboxymethylsulfanyl)propanoic acid;2,6-diaminohexanoic acid
• CAS: 79458-68-7
• 化学式: C11H23N3O6S
• 分子量: 325.38
• InChiKey: SAGXGPWVLUSDSQ-HVDRVSQOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.26
• 重原子数：
  21
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  215
• 氢给体数：
  6
• 氢受体数：
  10

文献信息

• COMPOSITION FOR THE TREATMENT OF OXIDATIVE STRESS
  申请人：Probiox SA

  公开号：EP2249867A2

  公开（公告）日：2010-11-17
• Mammalian mucinase, its recombinant production, and its use in therapy or prophylaxis against diseases in which mucus is involved or infectious diseases
  申请人：——

  公开号：US20040253224A1

  公开（公告）日：2004-12-16

  The invention provides a mammalian mucinase capable of hydrolyzing mucin. The mucinase is, among other things, suitable for counteracting diseases in which mucus is involved, such as cystic fibrosis, COPD, asthma, bronchitis, tuberculosis, tumors with altered mucus expression, and mucus-containing pathogens. The invention also provides a pharmaceutical composition comprising an effective amount of the mucinase and a method of therapeutic or prophylactic treatment of an individual against such a disease. Methods for obtaining the mucinase are also herewith provided, as well as nucleic acids encoding all or part of the mucinase. In one aspect, the invention provides a diagnostic kit comprising a mucinase, a mucinase-specific antibody, a mucinase-derived peptide, and/or nucleic acid encoding all or part of the mucinase.
• US8586629B2
  申请人：——

  公开号：US8586629B2

  公开（公告）日：2013-11-19
• [EN] COMPOSITION FOR THE TREATMENT OF OXIDATIVE STRESS<br/>[FR] COMPOSITION DESTINÉE À TRAITER LE STRESS OXYDATIF
  申请人：PROBIOX SA

  公开号：WO2009098072A2

  公开（公告）日：2009-08-13

  This invention is based on the observed oxidative stress and increased risk on cardiovascular diseases in subjects with increased lipid peroxidation, in particular with women using oral contraceptives and in hormone replacement therapies. The invention provides compositions and combinations, particularly useful in preventing and or reducing the increased lipid peroxidation in subjects in need thereof. These compositions are based on the synergistic combination of zinc and/or a hydroxyl radical scavenger in reducing lipid peroxidation.
• [EN] N-ACETYLCYSTEINE AMIDE (NAC AMIDE) FOR THE TREATMENT OF DISEASES AND CONDITIONS<br/>[FR] N-ACÉTYLCYSTÉINE AMIDE (NAC AMIDE) DESTINÉ AU TRAITEMENT DE MALADIES ET DE CONDITIONS
  申请人：GOLDSTEIN GLENN A

  公开号：WO2011044230A2

  公开（公告）日：2011-04-14

  Methods and compositions comprising N-acetylcysteine amide (NAC amide) and derivatives thereof are used in treatments and prophylactic therapies for human and non- human mammalian diseases, disorders, conditions and pathologies accociated with bomb blast or other high energy noise or impulse blasts. Pharmaceutically or physiologically acceptable compositions of NAC amide or derivatives thereof are also provided, which may be administered alone, or in combination with other suitable agents.