申请人:Konradi W. Andrei
公开号:US20080021056A1
公开(公告)日:2008-01-24
The invention provides compounds of formula I:
or pharmaceutically salts thereof where R
1
, R
2
, and the A, B, and C-rings are as defined herein. Compounds of formula I are useful in treating or preventing cognitive disorders, such as Alzheimer's disease. The invention also encompasses pharmaceutical compositions comprising compounds or salts of formula I, methods of preparing the desired compounds, and methods of treating cognitive disorders, such as Alzheimer's disease, using the compounds or salts of formula I.
该发明提供了公式I的化合物:
或其药用盐,其中R
1
,R
2
和A、B和C环如本文所定义。公式I的化合物在治疗或预防认知障碍,如阿尔茨海默病方面是有用的。该发明还涵盖了包括公式I的化合物或盐的药物组合物,制备所需化合物的方法,以及使用公式I的化合物或盐治疗认知障碍,如阿尔茨海默病的方法。