beta-D-吡喃半乳糖基-(1->3)-2-乙酰氨基-2-脱氧-beta-D-吡喃葡萄糖基-(1->3)-alpha-D-吡喃半乳糖 | 75645-27-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: beta-D-吡喃半乳糖基-(1->3)-2-乙酰氨基-2-脱氧-beta-D-吡喃葡萄糖基-(1->3)-alpha-D-吡喃半乳糖
• 英文名称: lacto-N-triose
• 英文别名: O⁴-[O³-(2-acetylamino-2-deoxy-β-D-glucopyranosyl)-β-D-galactopyranosyl]-D-glucose；O⁴-[O³-(2-Acetylamino-2-desoxy-β-D-glucopyranosyl)-β-D-galactopyranosyl]-D-glucose；Lacto-N-triose II；N-[(2S,3R,4R,5S,6R)-2-[(2R,3S,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl]oxyoxan-4-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
• CAS: 75645-27-1
• 化学式: C₂₀H₃₅NO₁₆
• 分子量: 545.495
• InChiKey: RJTOFDPWCJDYFZ-SPVZFZGWSA-N

物化性质

• 沸点：
  1022.4±65.0 °C(Predicted)
• 密度：
  1.66±0.1 g/cm3(Predicted)
• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  -6.6
• 重原子数：
  37
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  285
• 氢给体数：
  11
• 氢受体数：
  16

安全信息

• 危险性防范说明：
  P264,P280,P302+P352,P337+P313,P305+P351+P338,P362+P364,P332+P313
• 危险性描述：
  H315,H319

反应信息

• 作为产物：
  描述：

  在 palladium on activated charcoal 、 氢气 、 水 作用下， 以 甲醇 、 水 为溶剂， 以95%的产率得到beta-D-吡喃半乳糖基-(1->3)-2-乙酰氨基-2-脱氧-beta-D-吡喃葡萄糖基-(1->3)-alpha-D-吡喃半乳糖
  参考文献：
  名称：

  [EN] FUNCTIONALIZED HUMAN MILK OLIGOSACCHARIDES AND METHODS FOR PRODUCING THEM
  [FR] OLIGOSACCHARIDES DE LAIT MATERNEL FONCTIONNALISÉS ET LEURS PROCÉDÉS DE PRODUCTION

  摘要：

  New derivatives of human milk oligosaccharides and methods for preparing them are disclosed. Also described herein are hST6GALNAC V and hGCNT2-B variants, along with polynucleotides encoding the variants and host cells comprising the polynucleotides. Further provided herein are reaction mixtures comprising the hST6GALNAC V and hGCNT2-B variants.

  公开号：

  WO2023141513A2

文献信息

• [EN] FUNCTIONALIZED HUMAN MILK OLIGOSACCHARIDES AND METHODS FOR PRODUCING THEM<br/>[FR] OLIGOSACCHARIDES DE LAIT MATERNEL FONCTIONNALISÉS ET LEURS PROCÉDÉS DE PRODUCTION
  申请人：[en]THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

  公开号：WO2023141513A2

  公开（公告）日：2023-07-27

  New derivatives of human milk oligosaccharides and methods for preparing them are disclosed. Also described herein are hST6GALNAC V and hGCNT2-B variants, along with polynucleotides encoding the variants and host cells comprising the polynucleotides. Further provided herein are reaction mixtures comprising the hST6GALNAC V and hGCNT2-B variants.