3-(2,2,2-trifluoroethoxy)thiophene | 142214-50-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-(2,2,2-trifluoroethoxy)thiophene
• 英文别名: Thiophene, 3-(2,2,2-trifluoroethoxy)-
• CAS: 142214-50-4
• 化学式: C₆H₅F₃OS
• 分子量: 182.166
• InChiKey: MPKAOMIFYFZQFF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  37.5
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3-溴吡啶 、 4-溴氯苯 、 3-(2,2,2-trifluoroethoxy)thiophene 在 palladium diacetate 二环己烷并-18-冠醚-6 、 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 19.0h， 以30%的产率得到2-(3-pyridyl)-5-(4-chlorophenyl)-3-(2,2,2-trifluoroethoxy)thiophene
  参考文献：
  名称：

  Synthesis and evaluation of new arylbenzo[b]thiophene and diarylthiophene derivatives as inhibitors of the NorA multidrug transporter of Staphylococcus aureus

  摘要：

  The synthesis based on palladium catalytic coupling of 38 new-arylated benzo[b]thiophenes or thiophenes is described in a few steps. We also report the direct arylation of the position 3 of the benzo[b]thiophenic structure, a 'one pot' 2,5-heterodiarylation of thiophenes as well as the synthesis of precursors of amino-acids with a 2-arylated benzo[b]thiophene core. These compounds were evaluated on bacteria strains: most of them did not exhibit any antibiotic activity but were found to selectively inhibit the NorA multidrug transporter of Staphylococcus aureus. As such, they restored the activity of the NorA substrates ciprofloxacin against a resistant S. aureus strain in which this efflux pump is over-expressed. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2007.04.023

文献信息

• Non-aqueous ink compositions containing transition metal complexes, and uses thereof in organic electronics
  申请人：NISSAN CHEMICAL INDUSTRIES, LTD.

  公开号：US10870771B2

  公开（公告）日：2020-12-22

  Described herein are non-aqueous ink compositions containing a polythiophene having a repeating unit complying with formula (I) described herein, a transition metal complex having at least one β-diketonate ligand, and a liquid carrier having one or more organic solvents. The present disclosure also concerns the uses of such non-aqueous ink compositions, for example, in organic electronic devices.

  本文描述了非水性油墨组合物，该组合物包含具有符合本文所述式（I）重复单元的聚噻吩、具有至少一个β-二酮酸配体的过渡金属配合物以及具有一种或多种有机溶剂的液体载体。本公开还涉及此类非水性墨水组合物的用途，例如在有机电子设备中的用途。
• Mélanges de polymères polaires et de polymères conducteurs dédopés, procédés d'obtention de ces mélanges et utilisation de ces mélanges pour fabriquer des dispositifs électroniques optoélectriques, électrotechniques et électromécaniques
  申请人：SOLVAY (Société Anonyme)

  公开号：EP0473224B1

  公开（公告）日：1996-02-28
• IMPROVED SYNTHESIS OF CONJUGATED POLYMERS VIA OXIDATIVE POLYMERIZATION AND RELATED COMPOSITIONS
  申请人：Plextronics, Inc.

  公开号：EP2768868A1

  公开（公告）日：2014-08-27
• NON-AQUEOUS INK COMPOSITIONS CONTAINING TRANSITION METAL COMPLEXES, AND USES THEREOF IN ORGANIC ELECTRONICS
  申请人：Nissan Chemical Corporation

  公开号：EP3405534B1

  公开（公告）日：2020-10-14
• SYNTHESIS OF CONJUGATED POLYMERS VIA OXIDATIVE POLYMERIZATION AND RELATED COMPOSITIONS
  申请人：Plextronics, Inc.

  公开号：US20130109813A1

  公开（公告）日：2013-05-02

  An improved polymerization method including a method comprising providing a reaction mixture comprising a first monomer, an organic oxidant, and at least one Lewis acid or Brönsted acid, wherein the first monomer comprises at least one optionally substituted heterocyclic ring, wherein the heterocyclic ring comprises at least one heteroatom; and reacting the reaction mixture to obtain a conjugated polymer. The method can reduce the content of undesirable entities in the polymer such as halogens and metals, which can be useful in organic electronic device applications. Purification methods also are adapted to remove organic and inorganic impurities.