2-((E)-2-((2S,3S,5R,6R)-5,6-dimethoxy-5,6-dimethyl-3-((E)-prop-1-enyl)-1,4-dioxan-2-yl)vinyl)-6-hydroxybenzaldehyde | 1035190-76-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-((E)-2-((2S,3S,5R,6R)-5,6-dimethoxy-5,6-dimethyl-3-((E)-prop-1-enyl)-1,4-dioxan-2-yl)vinyl)-6-hydroxybenzaldehyde
• 英文别名: 2-[(E)-2-[(2S,3S,5R,6R)-5,6-dimethoxy-5,6-dimethyl-3-[(E)-prop-1-enyl]-1,4-dioxan-2-yl]ethenyl]-6-hydroxybenzaldehyde
• CAS: 1035190-76-1
• 化学式: C₂₀H₂₆O₆
• 分子量: 362.423
• InChiKey: LCMXLWDORSTXTM-KVRYMKADSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  74.2
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2-((E)-2-((2S,3S,5R,6R)-5,6-dimethoxy-5,6-dimethyl-3-((E)-prop-1-enyl)-1,4-dioxan-2-yl)vinyl)-6-hydroxybenzaldehyde 在 水 、 溶剂黄146 作用下， 以 四氢呋喃 为溶剂， 反应 14.0h， 以70%的产率得到苯(甲)醛,2-[(1E,3S,4S,5E)-3,4-二羟基-1,5-庚二烯-1-基]-6-羟基-
  参考文献：
  名称：

  A new synthesis of (−)-epipyriculol: a phytotoxic metabolite

  摘要：

  A convenient synthesis of the phytotoxic natural product epipyriculol has been accomplished in 17 steps from methyl L-tartrate. The synthetic strategy is based upon the use of a butanediacetal-protected scaffold as central core from which the alkenyl side chains were assembled. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.01.115
• 作为产物：
  描述：

  在 manganese(IV) oxide 作用下， 以 二氯甲烷 为溶剂， 反应 0.75h， 以17 mg的产率得到2-((E)-2-((2S,3S,5R,6R)-5,6-dimethoxy-5,6-dimethyl-3-((E)-prop-1-enyl)-1,4-dioxan-2-yl)vinyl)-6-hydroxybenzaldehyde
  参考文献：
  名称：

  A new synthesis of (−)-epipyriculol: a phytotoxic metabolite

  摘要：

  A convenient synthesis of the phytotoxic natural product epipyriculol has been accomplished in 17 steps from methyl L-tartrate. The synthetic strategy is based upon the use of a butanediacetal-protected scaffold as central core from which the alkenyl side chains were assembled. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.01.115

文献信息

• A new synthesis of (−)-epipyriculol: a phytotoxic metabolite
  作者：Antonio Leyva、Francesca E. Blum、Steven V. Ley

  DOI：10.1016/j.tet.2008.01.115

  日期：2008.5

  A convenient synthesis of the phytotoxic natural product epipyriculol has been accomplished in 17 steps from methyl L-tartrate. The synthetic strategy is based upon the use of a butanediacetal-protected scaffold as central core from which the alkenyl side chains were assembled. (C) 2008 Elsevier Ltd. All rights reserved.