2-octadecyloxythiophene | 62071-21-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-octadecyloxythiophene
• 英文别名: 2-(Octadecyloxy)thiophene；2-octadecoxythiophene
• CAS: 62071-21-0
• 化学式: C₂₂H₄₀OS
• 分子量: 352.625
• InChiKey: PJLMCXYGLMZXHP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.7
• 重原子数：
  24
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  37.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-octadecyloxythiophene 在 乙酸酐 、 trifluoroborane diethyl ether 作用下， 以 (2S)-N-methyl-1-phenylpropan-2-amine hydrate 为溶剂， 生成 2-acetyl-5-octadecyloxythiophene
  参考文献：
  名称：

  Hypolipidemic agents

  摘要：

  取代的噻吩羧酸和酯以及以下一般结构的药学上可接受的盐可用作降脂药物：##STR1##其中R从含有10到20个碳原子的直链或支链饱和碳氢链和含有10到20个碳原子和1到4个双键的直链或支链不饱和碳氢链中选择；R.sub.1从氢、含有1到6个碳原子的直链或支链较低烷基链、苄基、苯乙基、吡啶基甲基、含有3到6个碳原子的烷烃多基、1,2,3,4,5,6-环己烷六基和Z中选择；Z从##STR2##中选择；其中n是整数2或3；R.sub.2从含有1到4个碳原子的直链或支链较低烷基链和烷基羰基中选择，其中烷基部分含有1到4个碳原子且可能是直链或支链；R.sub.3从氢和含有1到4个碳原子的直链或支链较低烷基链中选择，但当R.sub.3为氢时，R.sub.2为烷基羰基；或当R.sub.2不是烷基羰基时，R.sub.2和R.sub.3与各自连接的氮原子一起形成从吡咯烷基、哌啶基、吗啉基和哌嗪基中选择的单环杂环基；或##STR3##其中整数m和p的总和等于3到5；且R.sub.4为含有1到4个碳原子的直链或支链较低烷基链；X为1到6的整数，但当R.sub.1为烷烃多基或1,2,3,4,5,6-环己烷六基时，X等于2到6，而当R.sub.1不是烷烃多基或1,2,3,4,5,6-环己烷六基时，X等于1。

  公开号：

  US04017514A1

文献信息

• Hypolipidemic agents
  申请人：Richardson-Merrell Inc.

  公开号：US04017514A1

  公开（公告）日：1977-04-12

  Substituted thiophenecarboxylic acids and esters and pharmaceutically acceptable salts thereof of the following general structure are useful as hypolipidemic agents: ##STR1## wherein R is selected from a straight or branched saturated hydrocarbon chain containing from 10 to 20 carbon atoms and a straight or branched unsaturated hydrocarbon chain containing from 10 to 20 carbon atoms and from 1 to 4 double bonds; R.sub.1 is selected from hydrogen, a straight or branched lower alkyl chain of from 1 to 6 carbon atoms, benzyl, phenethyl, pyridyl-methyl, alkane-poly-yl containing from 3 to 6 carbon atoms, 1,2,3,4,5,6-cyclohexanehexayl, and Z; Z is selected from ##STR2## wherein n is the integer 2 or 3; R.sub.2 is selected from a straight or branched lower alkyl chain of from 1 to 4 carbon atoms, and alkylcarbonyl wherein the alkyl moiety contains from 1 to 4 carbon atoms and may be straight or branched; R.sub.3 is selected from hydrogen and a straight or branched lower alkyl chain of from 1 to 4 carbon atoms with the proviso that when R.sub.3 is hydrogen, R.sub.2 is alkylcarbonyl; or when R.sub.2 is other than alkylcarbonyl, R.sub.2 and R.sub.3 taken together with the nitrogen atom to which each is attached form a monocyclic heterocyclic group selected from pyrrolidino, piperidino, morpholino, and piperazino; or ##STR3## wherein the sum of the integers m and p is equal to from 3 to 5; and R.sub.4 is a straight or branched lower alkyl chain of from 1 to 4 carbon atoms; X is an integer of from 1 to 6 with the proviso that when R.sub.1 is alkane-poly-yl or 1,2,3,4,5,6-cyclohexanehexayl, X is equal to from 2 to 6, and when R.sub.1 is other than alkane-poly-yl or 1,2,3,4,5,6-cyclohexanehexayl, X is equal to 1.

  取代的噻吩羧酸和酯以及以下一般结构的药学上可接受的盐可用作降脂药物：##STR1##其中R从含有10到20个碳原子的直链或支链饱和碳氢链和含有10到20个碳原子和1到4个双键的直链或支链不饱和碳氢链中选择；R.sub.1从氢、含有1到6个碳原子的直链或支链较低烷基链、苄基、苯乙基、吡啶基甲基、含有3到6个碳原子的烷烃多基、1,2,3,4,5,6-环己烷六基和Z中选择；Z从##STR2##中选择；其中n是整数2或3；R.sub.2从含有1到4个碳原子的直链或支链较低烷基链和烷基羰基中选择，其中烷基部分含有1到4个碳原子且可能是直链或支链；R.sub.3从氢和含有1到4个碳原子的直链或支链较低烷基链中选择，但当R.sub.3为氢时，R.sub.2为烷基羰基；或当R.sub.2不是烷基羰基时，R.sub.2和R.sub.3与各自连接的氮原子一起形成从吡咯烷基、哌啶基、吗啉基和哌嗪基中选择的单环杂环基；或##STR3##其中整数m和p的总和等于3到5；且R.sub.4为含有1到4个碳原子的直链或支链较低烷基链；X为1到6的整数，但当R.sub.1为烷烃多基或1,2,3,4,5,6-环己烷六基时，X等于2到6，而当R.sub.1不是烷烃多基或1,2,3,4,5,6-环己烷六基时，X等于1。
• Process for producing dispersion containing electroconductive polymer
  申请人：SHOWA DENKO K.K.

  公开号：US10563020B2

  公开（公告）日：2020-02-18

  A method for producing a conductive polymer-containing dispersion, the method including a polymerization step of subjecting a monomer that is to be a constitutional unit of a conjugated conductive polymer to a polymerization reaction in a mixed solution containing the monomer, a polyanion, and a dispersion medium to produce a polymerized product; and a dispersion treatment step of performing a dispersion treatment on a reaction solution obtained in the polymerization step to prepare a dispersion of the polymerized product, wherein a dispersion medium is added one or more times at any point in time from after the polymerization step to during the dispersion treatment step to make a mass concentration (B) of the polymerized product in the dispersion after the dispersion treatment step lower than a mass concentration (A) of the polymerized product in the reaction solution.

  一种生产含导电聚合物的分散液的方法，该方法包括聚合步骤：在含有单体、聚阴离子和分散介质的混合溶液中，将作为共轭导电聚合物构型单元的单体进行聚合反应，生成聚合产物；分散处理步骤：对聚合步骤中得到的反应溶液进行分散处理，以制备聚合产物的分散液，其中在聚合步骤后至分散处理步骤期间的任意时间点添加一次或多次分散介质，以使分散处理步骤后分散液中聚合产物的质量浓度（B）低于反应溶液中聚合产物的质量浓度（A）。
• US4011333A
  申请人：——

  公开号：US4011333A

  公开（公告）日：1977-03-08
• US4017514A
  申请人：——

  公开号：US4017514A

  公开（公告）日：1977-04-12
• [EN] METHOD OF CROSSLINKING INTRINSICALLY CONDUCTIVE POLYMERS OR INTRINSICALLY CONDUCTIVE POLYMER PRECURSORS AND THE ARTICLES OBTAINED THEREFROM<br/>[FR] PROCEDE DE RETICULATION DE POLYMERES INTRINSEQUEMENT CONDUCTEURS OU DE PRECURSEURS DE POLYMERES INTRINSEQUEMENT CONDUCTEURS, ET ARTICLES REALISES A PARTIR DE CES PRODUITS
  申请人：UNIV CONNECTICUT

  公开号：WO2005014693A1

  公开（公告）日：2005-02-17

  A method of manufacturing an intrinsically conductive polymer crosslinking at least a portion of an intrinsically conductive polymer precursor in the solid state, the swollen state, or combinations comprising at least one of the foregoing states, wherein the swollen state is characterized as being one wherein the intrinsically conductive polymer precursor increases in volume upon exposure to a solvent without completely dissolving in the solvent. In another embodiment, a method of manufacturing a pattern comprises casting a film of an intrinsically conductive polymer precursor on a substrate; and crosslinking at least a portion of the film by oxidation, wherein the crosslinking occurs in the solid state, the swollen state or combinations comprising at least one of the foregoing states.