6-phenacylbenzo<1,7>naphthyridinium bromide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-phenacylbenzo<1,7>naphthyridinium bromide
• 英文别名: 6-phenacylbenzo[f]-1,7-naphthyridinium bromide；2-benzo[f][1,7]naphthyridin-6-ium-6-yl-1-phenylethanone;bromide
• 化学式: Br*C₂₀H₁₅N₂O
• 分子量: 379.256
• InChiKey: AHEYKCWFBNUSFW-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.56
• 重原子数：
  24.0
• 可旋转键数：
  3.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  33.84
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  6-phenacylbenzo<1,7>naphthyridinium bromide 在 ammonium acetate 、 三氯化铁 、 溶剂黄146 作用下， 反应 6.0h， 以38%的产率得到2-phenylbenzo[f]imidazo[1,2-h]-1,7-naphthyridine
  参考文献：
  名称：

  摘要：

  The authors discuss the preparation of benzoimidazonaphyridines (see Figure for example) via a cyclization reaction between ammonium acetate and a series of quaternary N-phenacylbenzonaphthyridinium bromides Imidazoisoquinolines were shown to exhibit pregnancy-terminating activity in hamsters and rats. The authors anticipate similar interesting applications for benzoimidazonaphthyridines.

  DOI：

  10.1071/ch00127
• 作为产物：
  描述：

  苯并[f][1,7]萘啶 、 2-溴苯乙酮 生成 6-phenacylbenzo<1,7>naphthyridinium bromide
  参考文献：
  名称：

  摘要：

  The authors discuss the preparation of benzoimidazonaphyridines (see Figure for example) via a cyclization reaction between ammonium acetate and a series of quaternary N-phenacylbenzonaphthyridinium bromides Imidazoisoquinolines were shown to exhibit pregnancy-terminating activity in hamsters and rats. The authors anticipate similar interesting applications for benzoimidazonaphthyridines.

  DOI：

  10.1071/ch00127

文献信息

• 1,3-Dipolar Cycloaddition Reactions of the Ylide Derived from 6-Phenacyl-benzo[f][1,7]naphthyridinium Bromide
  作者：Grazyna Matusiak

  DOI：10.1071/c98109

  日期：——

  The 1,3-dipolar cycloaddition reactions of 4,6-diazaphenanthrene 6-phenacylide formed in situ from the quaternary 6-phenacylbenzo[f][1,7]naphthyridinium bromide in basic medium were examined; methacrylic acid, methyl methacrylate, butyl vinyl ether, methyl vinyl ketone, maleic anhydride and dimethyl acetylenedicarboxylate were used as the dipolarophiles.

  4,6-二氮杂蒽-6-苯乙酰基的 1,3-二极环化反应 的1,3-二极环加成反应。 6-苯酰基苯并[f][1,7]萘啶鎓在碱性介质中的 在碱性介质中形成的6-苯并苯并[f][1,7]萘啶季化合物；甲基丙烯酸、甲基丙烯酸甲酯、 甲基丙烯酸、甲基丙烯酸甲酯、丁基乙烯基醚、甲基乙烯基酮、马来酸酐和二甲 甲基丙烯酸甲酯、丁基乙烯基醚、甲基乙烯基酮、马来酸酐和乙炔二甲酸二甲酯被用作双极性亲和剂。
• 1,3-Dipolar cycloaddition reactions of 4,6-diazaphenanthrene 6-phenacylide
  作者：Graźyna Matusiak、Wanda Śliwa

  DOI：10.1007/bf00808675

  日期：1993.2

  The 1,3-dipolar cycloaddition reactions of 4,6-diazaphenanthrene 6-phenacylide formed in situ from the appropriate quaternary bromide in basic medium were investigated; as dipolarophiles acrylonitrile, ethyl acrylate, n-butyl acrylate and diethyl maleate were used.
• ——
  作者：Barbara Bachowska、Teresa Zujewska、Barbara Bachowska、Teresa Zujewska、Barbara Bachowska、Teresa Zujewska

  DOI：10.1071/ch00127

  日期：——

  The authors discuss the preparation of benzoimidazonaphyridines (see Figure for example) via a cyclization reaction between ammonium acetate and a series of quaternary N-phenacylbenzonaphthyridinium bromides Imidazoisoquinolines were shown to exhibit pregnancy-terminating activity in hamsters and rats. The authors anticipate similar interesting applications for benzoimidazonaphthyridines.