5-ethyl-2,2,5-trimethyl-1,3-dioxane

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-ethyl-2,2,5-trimethyl-1,3-dioxane
• 化学式: C₉H₁₈O₂
• 分子量: 158.241
• InChiKey: ASCMNVZPVSEWBB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-乙基-2-甲基-1,3-丙二醇 、 丙酮 在 对甲苯磺酸 作用下， 以 苯 为溶剂， 以70%的产率得到5-ethyl-2,2,5-trimethyl-1,3-dioxane
  参考文献：
  名称：

  The Stereochemistry of Some New Flexible 2,2,5,5-Tetrasubstituted 1,3-Dioxanes

  摘要：

  DOI：

  10.1007/pl00013481

文献信息

• [EN] OLEIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION OR FOOD COMPOSITION COMPRISING SAID OLEIC ACID DERIVATIVES, AND THEIR USES<br/>[FR] DÉRIVÉS D'ACIDE OLÉIQUE, COMPOSITION PHARMACEUTIQUE OU COMPOSITION ALIMENTAIRE COMPRENANT LESDITS DÉRIVÉS D'ACIDE OLÉIQUE, ET LEURS UTILISATIONS
  申请人：UNIV BOURGOGNE

  公开号：WO2019228994A1

  公开（公告）日：2019-12-05

  This invention relates to oleic acid derivative comprising a hydrophobic part C17H33 linked to a particular polar head part "A", especially for use as a medicament, for instance, for the treatment of a disorder caused by the GPR120 receptor and/or the CD36 receptor, comprising administering to a subject in need thereof a therapeutically effective amount of said oleic acid derivative or of said pharmaceutical composition. The invention also relates to the use of said oleic acid derivative as a food composition.

  这项发明涉及一种油酸衍生物，其中包括一个与特定极性头部"A"连接的疏水部分C17H33，特别用作药物，例如，用于治疗由GPR120受体和/或CD36受体引起的疾病，包括向需要的受试者施用所述油酸衍生物或所述药物组合的治疗有效量。该发明还涉及将所述油酸衍生物用作食品组成的用途。
• Fluorene Derivative, Method for Producing the Same, Resin Composition, and Article
  申请人：DEXERIALS CORPORATION

  公开号：US20180215969A1

  公开（公告）日：2018-08-02

  A fluorene derivative represented by General Formula (1) below. X 1 —Y—X 2 General Formula (1) In the General Formula (1), X 1 represents a cyclic carbonate group including a carbonate bond [—O—C(═O)—O—], X 2 represents a cyclic carbonate group including a carbonate bond [—O—C(═O)—O—], and Y represents a bivalent group including a 9,9-bisaryl fluorene skeleton.

  根据您提供的信息，翻译成中文的结果如下： 由下式（1）表示的芴衍生物。 X1 —Y—X2 式（1） 在式（1）中，X1代表包含碳酸酯键（—O—C(═O)—O—）的环状碳酸酯基团，X2也代表包含碳酸酯键（—O—C(═O)—O—）的环状碳酸酯基团，而Y代表包含9,9-二芳基芴骨架的二价基团。
• Immunoproteasome inhibitors
  申请人：Principia Biopharma Inc.

  公开号：US11225493B2

  公开（公告）日：2022-01-18

  Provided herein are compounds, such as a compound of Formula (I), or a pharmaceutically acceptable salt thereof, that are immunoproteasome (such as LMP2 and LMP7) inhibitors. The compounds described herein can be useful for the treatment of diseases treatable by inhibition of immunoproteasomes. Also provided herein are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

  本文提供的化合物，如式（I）化合物或其药学上可接受的盐，是免疫蛋白酶体（如 LMP2 和 LMP7）抑制剂。本文所述化合物可用于治疗可通过抑制免疫蛋白酶体治疗的疾病。本文还提供了含有此类化合物的药物组合物和制备此类化合物的工艺。
• IMMUNOPROTEASOME INHIBITORS
  申请人：Principia Biopharma Inc.

  公开号：US20200277312A1

  公开（公告）日：2020-09-03

  Provided herein are compounds, such as a compound of Formula (I), or a pharmaceutically acceptable salt thereof, that are immunoproteasome (such as LMP2 and LMP7) inhibitors. The compounds described herein can be useful for the treatment of diseases treatable by inhibition of immunoproteasomes. Also provided herein are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
• LINOLEIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION OR FOOD COMPOSITION COMPRISING SAID LINOLEIC ACID DERIVATIVES, AND THEIR USES
  申请人：UNIVERSITÉ DE BOURGOGNE

  公开号：US20210155640A1

  公开（公告）日：2021-05-27

  Disclosed is a linoleic acid derivative of Formula (I) below including a hydrophobic part C 17 H 31 linked to a polar head part “A”: wherein the polar head part A is selected from A 1 to A 4 below: or a pharmaceutically/food quality acceptable salt thereof.

表征谱图