5-ethoxyhex-1-ene

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-ethoxyhex-1-ene
• 化学式: C₈H₁₆O
• 分子量: 128.214
• InChiKey: BANQRFPBICVWGJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  5-己烯-2-醇 、 碘乙烷 在 六甲基磷酰三胺 、 potassium hydride 作用下， 以 乙醚 为溶剂， 以57%的产率得到5-ethoxyhex-1-ene
  参考文献：
  名称：

  Formation of Some Oxygen-Containing Heterocycles by Radical Cyclization:  The Stereochemical Influence of Anomeric Effects

  摘要：

  The influence of the anomeric effect on radical cyclization has been examined by determining the stereochemical outcome of the ring closure of 10 suitably substituted radicals. The stereochemistry of the products formed from the acyclic precursors 4a-f indicates that for suitably constituted radicals anomeric interactions stabilize pseudoaxially substituted transition structures 14 thus affording products with stereochemistry the reverse of that normally observed.

  DOI：

  10.1021/jo980359u

文献信息

• Formation of Some Oxygen-Containing Heterocycles by Radical Cyclization:  The Stereochemical Influence of Anomeric Effects
  作者：Athelstan L. J. Beckwith、Dennis M. Page

  DOI：10.1021/jo980359u

  日期：1998.7.1

  The influence of the anomeric effect on radical cyclization has been examined by determining the stereochemical outcome of the ring closure of 10 suitably substituted radicals. The stereochemistry of the products formed from the acyclic precursors 4a-f indicates that for suitably constituted radicals anomeric interactions stabilize pseudoaxially substituted transition structures 14 thus affording products with stereochemistry the reverse of that normally observed.