丙酸氟替卡松EP杂质F | 1219174-94-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 中文名称: 丙酸氟替卡松EP杂质F
• 中文别名: 氟替卡松杂质F
• 英文名称: 6alpha,9-Difluoro-17-(((fluoromethyl)sulfanyl)carbonyl)-16alpha-methyl-3,11-dioxoandrosta-1,4-dien-17alpha-yl propanoate
• 英文别名: [(6S,8S,9R,10S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-10,13,16-trimethyl-3,11-dioxo-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] propanoate
• CAS: 1219174-94-3
• 化学式: C₂₅H₂₉F₃O₅S
• 分子量: 498.6
• InChiKey: RGGLGWLQXMGICO-HOERUVBCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  34
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  103
• 氢给体数：
  0
• 氢受体数：
  9

文献信息

• [EN] GLUCOCORTICOID DRUGS AS SMOOTHENED AGONISTS<br/>[FR] MÉDICAMENTS GLUCOCORTICOÏDES UTILISÉS EN TANT QU'AGONISTES LISSÉS
  申请人：UNIV DUKE

  公开号：WO2011109711A1

  公开（公告）日：2011-09-09

  Described herein are methods of stimulating the proliferation of stem cells using glucocorticoid compounds. Also disclosed are related methods of use and treatment, for example, methods of stimulating hair growth, methods of regenerating or repairing damaged tissue, methods of treating disorders such as Parkinson's disease, and methods of promoting wound healing, comprising administration of a glucocorticoid compound or a composition comprising the compound.