α-maltotriosyl α-maltotrioside

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: α-maltotriosyl α-maltotrioside
• 英文别名: (2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-5-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• 化学式: C₃₆H₆₂O₃₁
• 分子量: 990.87
• InChiKey: VHHHRPCZZVNWNC-DWJDYNGGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -12.8
• 重原子数：
  67
• 可旋转键数：
  16
• 环数：
  6.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  506
• 氢给体数：
  20
• 氢受体数：
  31

反应信息

• 作为产物：
  描述：

  海藻糖 、 α-环糊精 在 cyclomaltodextrine glucanotransferase from Bacillus stearothermophilus,2.) β-amilase 作用下， 生成 α-maltosyl α-glucoside 、 麦芽糖基海藻糖 、 bis-(O⁴-α-D-glucopyranosyl-α-D-glucopyranosyl)-ether 、 α-maltotriosyl α-maltotrioside
  参考文献：
  名称：

  Synthesis of Glycosyl-trehaloses by Cyclomaltodextrin Glucanotransferase through the Transglycosylation Reaction

  摘要：

  嗜热脂肪芽孢杆菌的环麦芽糊精葡聚糖转移酶以环己糖为糖基供体，以曲哈糖为受体，通过转糖基化反应产生了一系列糖基曲哈糖。经过β-淀粉酶处理后，通过柱层析分离出了五种糖基-曲哈糖。经过化学和酶学分析，这些低聚糖分别是 α-麦芽糖基 α-d-吡喃葡萄糖苷、α-麦芽三糖基 α-d-吡喃葡萄糖苷、α-麦芽糖基 α-麦芽糖苷、α-麦芽三糖基 α-麦芽糖苷和 α-麦芽三糖基 α-麦芽三糖苷。这些物质不会被唾液淀粉酶、人工胃液或胰淀粉酶水解，但会被小肠酶水解。

  DOI：

  10.1271/bbb.61.1146

文献信息

• Synthesis of Glycosyl-trehaloses by Cyclomaltodextrin Glucanotransferase through the Transglycosylation Reaction
  作者：Masashi Kurimoto、Akihiko Tabuchi、Takahiko Mandai、Takashi Shibuya、Hiroto Chaen、Shigeharu Fukuda、Toshiyuki Sugimoto、Yoshio Tsujisaka

  DOI：10.1271/bbb.61.1146

  日期：1997.1

  Cyclomaltodextrin glucanotransferase from Bacillus stearothermophilus produced a series of glycosyl-trehaloses through the transglycosylation reaction with cyclomaltohexaose as the glycosyl donor and trehalose as its acceptor. After β-amylase treatment, five species of glycosyl-trehaloses were isolated by column chromatography. After chemical and enzymatic analyses, it was concluded that these oligosaccharides were α-maltosyl α-d-glucopyranoside, α-maltotriosyl α-d-glucopyranoside, α-maltosyl α-maltoside, α-maltotriosyl α-maltoside, and α-maltotriosyl α-maltotrioside. These were not hydrolyzed by salivary amylase, artificial gastric juice, or pancreatic amylase, however they were hydrolyzed by enzymes of the small intestine.

  嗜热脂肪芽孢杆菌的环麦芽糊精葡聚糖转移酶以环己糖为糖基供体，以曲哈糖为受体，通过转糖基化反应产生了一系列糖基曲哈糖。经过β-淀粉酶处理后，通过柱层析分离出了五种糖基-曲哈糖。经过化学和酶学分析，这些低聚糖分别是 α-麦芽糖基 α-d-吡喃葡萄糖苷、α-麦芽三糖基 α-d-吡喃葡萄糖苷、α-麦芽糖基 α-麦芽糖苷、α-麦芽三糖基 α-麦芽糖苷和 α-麦芽三糖基 α-麦芽三糖苷。这些物质不会被唾液淀粉酶、人工胃液或胰淀粉酶水解，但会被小肠酶水解。