β-[1'''-hydroxyisopropyl]-4,2’,4’-trihydroxy-6’-methoxy-3’-prenyl-α,β-dihydrochalkon

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: β-[1'''-hydroxyisopropyl]-4,2’,4’-trihydroxy-6’-methoxy-3’-prenyl-α,β-dihydrochalkon
• 英文别名: 1-[2,4-Dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-4-hydroxy-3-(4-hydroxyphenyl)-4-methylpentan-1-one；1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-4-hydroxy-3-(4-hydroxyphenyl)-4-methylpentan-1-one
• 化学式: C₂₄H₃₀O₆
• 分子量: 414.499
• InChiKey: HLUJAQHRIXGLIM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  30
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  黄腐酚 、 异丙醇 在 4,4'-二甲氧基二苯甲酮 作用下， 以 丙酮 为溶剂， 反应 1.5h， 以37%的产率得到β-[1'''-hydroxyisopropyl]-4,2’,4’-trihydroxy-6’-methoxy-3’-prenyl-α,β-dihydrochalkon
  参考文献：
  名称：

  Photochemical transformations of xanthohumol

  摘要：

  A photoinduced procedure for the addition of simple alcohols to xanthohumol, the major prenylated flavonoid of hop plants, has been developed. The reaction is regioselective, simple, and occurs in one pot to afford two new beta adducts of xanthohumol. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.08.072

文献信息

• Photochemical transformations of xanthohumol
  作者：Jarosław Popłoński、Tomasz Tronina、Ewa Huszcza

  DOI：10.1016/j.tetlet.2013.08.072

  日期：2013.11

  A photoinduced procedure for the addition of simple alcohols to xanthohumol, the major prenylated flavonoid of hop plants, has been developed. The reaction is regioselective, simple, and occurs in one pot to afford two new beta adducts of xanthohumol. (C) 2013 Elsevier Ltd. All rights reserved.