9-cis-13-trans-15-cis-octadecatrienoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 9-cis-13-trans-15-cis-octadecatrienoic acid
• 英文别名: 9Z,13E,15Z-octadecatrieonic acid；9Z,13E,15Z-C18:3；Isorumelenic acid；(9Z,13E,15Z)-octadeca-9,13,15-trienoic acid
• 化学式: C₁₈H₃₀O₂
• 分子量: 278.435
• InChiKey: REOBRTYMNNYVNT-NZCJRGAMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  20
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  linseed oil 生成 9-cis-13-trans-15-cis-octadecatrienoic acid 、 十八碳-9-顺式,11-反式,13-反式-三烯酸 、 10,12,14-C18:3 、 10E,12Z,14E-C18:3 、 油酸 、 共轭亚油酸 、 共轭亚油酸 、 十八烷酸 、 (Z,Z)-9,12-十八烷二烯酸二聚物 、 Γ-十八碳三烯酸 、 9-(6-propyl-cyclohexa-2,4-dienyl)-nonanoic acid 、 rumelenic acid 、 棕榈酸 、 硬脂酸
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• [EN] NEW CONJUGATED LINOLENIC ACIDS AND METHODS FOR COMMERCIAL PREPARATION AND PURIFICATION<br/>[FR] NOUVEAUX ACIDES LINOLENIQUES CONJUGUES ET PROCEDES DE PREPARATION ET DE PURIFICATION A DES FINS COMMERCIALES
  申请人：UNIV LAVAL

  公开号：WO2004013078A1

  公开（公告）日：2004-02-12

  A method for the preparation and purification of conjugated linolenic acids is described. The method comprises blending a mixture of vegetable oils and or fats including various concentrations of alpha or gamma and or both linolenic acids with a base. The method transforms approximately over two thirds of α-linolenic acid (9Z,12Z,15Z-octadecatrienoic acid) into 9Z,11E,15Z-octadecatrienoic acid and 9Z,13E,15Z-octadecatrienoic acid. The method also transforms gamma-linolenic acid (6Z,9Z,12Z-octadecatrienoic acid) into 6Z,8E,15Z-octadeccatrienoic acid and 6Z,10E,12Z-octadecatrienoic acid. In all cases, geometrical isomers and fully conjugated isomers are also produced.

  描述了一种制备和纯化共轭亚麻酸的方法。该方法包括混合一种包括各种浓度的α或γ或两者亚麻酸的植物油和/或脂肪的混合物与一种碱。该方法将大约三分之二的α-亚麻酸（9Z,12Z,15Z-八十八碳三烯酸）转化为9Z,11E,15Z-八十八碳三烯酸和9Z,13E,15Z-八十八碳三烯酸。该方法还将γ-亚麻酸（6Z,9Z,12Z-八十八碳三烯酸）转化为6Z,8E,15Z-八十八碳三烯酸和6Z,10E,12Z-八十八碳三烯酸。在所有情况下，还会产生几何异构体和完全共轭异构体。
• NEW CONJUGATED LINOLENIC ACIDS AND METHODS FOR COMMERCIAL PREPARATION AND PURIFICATION
  申请人：Université Laval

  公开号：EP1546082A1

  公开（公告）日：2005-06-29
• Conjugated linolenic acids and methods for commerical preparation and purification
  申请人：Angers Paul

  公开号：US20060281814A1

  公开（公告）日：2006-12-14

  A method for the preparation and purification of conjugated linolenic acids is described. The method comprises blending a mixture of vegetable oils and or fats including various concentrations of alpha or gamma and or both linolenic acids with a base. The method transforms approximately over two thirds of α-linolenic acid (9Z,12Z,15Z-octadecatrienoic acid) into 9Z,11E,15Z-octadecatrienoic acid and 9Z,13E,15Z-octadecatrienoic acid. The method also transforms gamma-linolenic acid (6Z,9Z,12Z-octadecatrienoic acid) into 6Z,8E,15Z-octadeccatrienoic acid and 6Z,10E,12Z-octadecatrienoic acid. In all cases, geometrical isomers and fully conjugated isomers are also produced.
• Conjugated linolenic acids and methods of preparation and purification and uses thereof
  申请人：Galvez Garro Juan-Miguel

  公开号：US20060281815A1

  公开（公告）日：2006-12-14

  This invention relates to a new conjugated linoleic acids, a process for preparation thereof and method of use. Thus this invention is concerned with the preparation and purification of conjugated linoleic acids from materials rich in alpha or gamma linoleic acids. The reaction produces a mixture containing a 1:1 ratio of 9Z, 11E, 15Z-octadecatrienoic acid and 9Z, 13E, 15Z-octadecatrieonic acid. The mixture can be purified up to 90% by liquid chromatography, crystallization or urea crystallization. The mixture of 1:1 9Z, 11E, 15Z-octadecatrienoic acid and 9Z, 13E, 15E, 15Z-octadecatrienoic acid have anticancerous activities.
• US7417159B2
  申请人：——

  公开号：US7417159B2

  公开（公告）日：2008-08-26