N-acridin-9-yl-D-alanine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N-acridin-9-yl-D-alanine
• 英文别名: (2R)-2-(acridin-9-ylamino)propanoic acid
• 化学式: C₁₆H₁₄N₂O₂
• 分子量: 266.299
• InChiKey: RCZYELJPFQVDCP-SNVBAGLBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  66.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  9-甲氧基吖啶 、 D-丙氨酸 以 甲醇 为溶剂， 反应 10.0h， 以80%的产率得到N-acridin-9-yl-D-alanine
  参考文献：
  名称：

  Lyakhov; Suveyzdis; Bykhovskaya, Pharmazie, 1997, vol. 52, # 7, p. 560 - 561

  摘要：

  DOI：

文献信息

• ADSORBING PATHOGEN-INACTIVATING COMPOUNDS WITH POROUS PARTICLES IMMOBILIZED IN A MATRIX
  申请人：HEI Derek J.

  公开号：US20100133160A1

  公开（公告）日：2010-06-03

  Methods and devices are provided for reducing the concentration of low molecular weight compounds in a biological composition containing cells while substantially maintaining a desired biological activity of the biological composition. The device comprises highly porous adsorbent particles, and the adsorbent particles are immobilized by an inert matrix. The matrix containing the particles is contained in a housing, and the particles range in diameter from about 100 μm to about 1500 μm. The device can be used to adsorb and remove a pathogen-inactivating compounds from a biological composition such as a blood product.