辛基酚聚醚-9 | 42173-90-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 辛基酚聚醚-9
• 英文名称: nonoxynol-9
• 英文别名: 26-(nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol；2-[2-[2-[2-[2-[2-[2-[2-[2-(4-Octylphenoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
• CAS: 42173-90-0
• 化学式: C₃₂H₅₈O₁₀
• 分子量: 602.807
• InChiKey: LFDLTLMEBDARLN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  42
• 可旋转键数：
  34
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  103
• 氢给体数：
  1
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  辛基酚聚醚-9 、 sodium 2-hydroxyethanesulfonate 在 硫酸 作用下， 以 二甲基亚砜 为溶剂， 以82.98 %的产率得到
  参考文献：
  名称：

  CN115160191

  摘要：

  公开号：

文献信息

• PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS
  申请人：Philippe Michel

  公开号：US20100028280A1

  公开（公告）日：2010-02-04

  The invention relates to a process for straightening keratin fibres, comprising: (i) a step in which a straightening composition containing at least two denaturing agents is applied to the keratin fibres, (ii) a step in which the temperature of the keratin fibres is raised, using a heating means, to a temperature of between 110 and 250° C.

  该发明涉及一种直发角蛋白纤维的拉直过程，包括：(i)将至少两种变性剂含有的拉直组合物涂抹到角蛋白纤维上的步骤，(ii)使用加热装置将角蛋白纤维的温度升高至110至250°C的步骤。
• MICROFLUIDIC PROTEIN CRYSTALLOGRAPHY
  申请人：Hansen Carl L.

  公开号：US20110306522A1

  公开（公告）日：2011-12-15

  The use of microfluidic structures enables high throughput screening of protein crystallization. In one embodiment, an integrated combinatoric mixing chip allows for precise metering of reagents to rapidly create a large number of potential crystallization conditions, with possible crystal formations observed on chip. In an alternative embodiment, the microfluidic structures may be utilized to explore phase space conditions of a particular protein crystallizing agent combination, thereby identifying promising conditions and allowing for subsequent focused attempts to obtain crystal growth.

  微流控结构的使用使得蛋白质结晶的高通量筛选成为可能。在一种实施方式中，集成的组合混合芯片允许精确计量试剂，以快速创建大量可能的结晶条件，并在芯片上观察到可能的晶体形成。在另一种实施方式中，微流控结构可以用于探索特定蛋白质结晶剂组合的相空间条件，从而确定有前途的条件，并允许随后集中尝试获得晶体生长。
• HIGH THROUGHPUT SCREENING OF CRYSTALLIZATION OF MATERIALS
  申请人：California Institute of Technology

  公开号：US20140041727A1

  公开（公告）日：2014-02-13

  High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels.

  通过将目标材料的溶液同时引入微型流体装置的多个腔室中，实现对目标材料结晶的高通量筛选。然后，操纵微型流体装置来改变腔室中的溶液条件，从而同时提供大量的结晶环境。改变溶液条件的控制可以采用各种技术，包括但不限于通过体积排斥将结晶剂体积计量到腔室中，通过微型加工结构的尺寸确定结晶剂体积的困扰，或通过交叉正交流道定义的连接点阵列中的样品和结晶剂的交叉通道注入。
• Nucleotide sequences useful as type-specific probes, PCR primers and LCR probes for the amplification and detection of human papilloma virus, and related kits and methods
  申请人：ABBOTT LABORATORIES

  公开号：EP0477972A2

  公开（公告）日：1992-04-01

  Short nucleotide sequences of human papilloma virus useful for the determination of the presence and type of human papilloma virus present in a test sample. The sequences provided can be amplified by polymerase chain reaction or ligase chain reaction. The sequences provided also can be hybridized by standard slot-, dot- or replica-blot procedures. Methods and kits also are provided for the detection of human papilloma virus in a test sample and the determination of the type of human papilloma virus present in the test sample.

  人类乳头瘤病毒的短核苷酸序列，用于确定检测样本中是否存在人类乳头瘤病毒以及病毒的类型。所提供的序列可通过聚合酶链反应或连接酶链反应进行扩增。所提供的序列还可以通过标准的槽式、点式或复制印迹程序进行杂交。此外，还提供了检测检测样本中人类乳头瘤病毒和确定检测样本中人类乳头瘤病毒类型的方法和试剂盒。
• Stabilization of biomolecules in samples
  申请人：Roche Diagnostics GmbH

  公开号：EP1584923A2

  公开（公告）日：2005-10-12

  This invention generally relates to stabilized non-blood-based samples in which microbial biomolecules in non-blood-based samples are stable at high temperatures. The stabilized non-blood-based samples include effective amounts of stabilization components to stabilize the microbial biomolecules in the samples. Stabilization components are typically effective at low levels in these stabilized non-blood-based samples. This provides the advantage of minimizing reagent expenses related to the stabilized non-blood-based samples of the invention. The invention also provides methods of stabilizing microbial biomolecules in non-blood-based samples and related kits.

  本发明一般涉及稳定的非血液基样品，其中非血液基样品中的微生物生物大分子在高温下保持稳定。稳定化的非血液样本包括有效量的稳定化成分，以稳定样本中的微生物生物大分子。在这些稳定的非血液样本中，稳定成分的有效含量通常较低。这样做的好处是可以最大限度地减少与本发明稳定化非血液样本相关的试剂支出。本发明还提供了稳定非血液样本中微生物生物大分子的方法及相关试剂盒。