hexa(ethylene glycol) bis(4-vinylbenzyl) ether

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: hexa(ethylene glycol) bis(4-vinylbenzyl) ether
• 英文别名: 1-Ethenyl-4-[2-[2-[2-[2-[2-[2-[(4-ethenylphenyl)methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzene
• 化学式: C₃₀H₄₂O₇
• 分子量: 514.659
• InChiKey: ONIAOGWGJADGDO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  37
• 可旋转键数：
  24
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  64.6
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  六甘醇 、 4-氯甲基苯乙烯 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以66%的产率得到hexa(ethylene glycol) bis(4-vinylbenzyl) ether
  参考文献：
  名称：

  Solvent and Reagent Accessibility within Oligo(ethylene glycol) Ether [PEG] Cross-Linked Polystyrene Beads

  摘要：

  alpha,omega-Bis-4(vinylbenzyl) ethers of mono-, di-, tetra-, and hexa(ethylene glycol) were used as cross-linkers in polystyrene beads to examine the influence of glycol tether length and % incorporation upon polymer swelling and reagent diffusion. Swelling of 2, 10, and 20% cross-linked poly{styrene-co-[oligo(ethylene glycol) bis(4-vinylbenzyl)ether]} (PS -PEG) beads was determined to be higher or comparable to 2% cross-linked poly[styrene-co-divinylbenzene] (2% PS-DVB) beads. Fluorescence quenching of polymer-bound dansyl groups by Et3O . BF4 indicated that the most rapid intraresin diffusion of this electrophilic reagent occurred in toluene. PS-PEG beads exhibited faster quenching than 2% PS-DVB in poor swelling solvents but were slower to quench than 2% PS-DVB in toluene.

  DOI：

  10.1021/jo980285m

文献信息

• Solvent and Reagent Accessibility within Oligo(ethylene glycol) Ether [PEG] Cross-Linked Polystyrene Beads
  作者：Mark E. Wilson、Kolja Paech、Wen-Jing Zhou、Mark J. Kurth

  DOI：10.1021/jo980285m

  日期：1998.7.1

  alpha,omega-Bis-4(vinylbenzyl) ethers of mono-, di-, tetra-, and hexa(ethylene glycol) were used as cross-linkers in polystyrene beads to examine the influence of glycol tether length and % incorporation upon polymer swelling and reagent diffusion. Swelling of 2, 10, and 20% cross-linked polystyrene-co-[oligo(ethylene glycol) bis(4-vinylbenzyl)ether]} (PS -PEG) beads was determined to be higher or comparable to 2% cross-linked poly[styrene-co-divinylbenzene] (2% PS-DVB) beads. Fluorescence quenching of polymer-bound dansyl groups by Et3O . BF4 indicated that the most rapid intraresin diffusion of this electrophilic reagent occurred in toluene. PS-PEG beads exhibited faster quenching than 2% PS-DVB in poor swelling solvents but were slower to quench than 2% PS-DVB in toluene.