catechin-(6->6')-catechin

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: catechin-(6->6')-catechin
• 英文别名: (2R,3S)-2-(3,4-dihydroxyphenyl)-6-[4,5-dihydroxy-2-[(2R,3S)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]phenyl]-3,4-dihydro-2H-chromene-3,5,7-triol
• 化学式: C₃₀H₂₆O₁₂
• 分子量: 578.529
• InChiKey: RIGUICSQBGRGSL-BAAZAXTHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  42
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  221
• 氢给体数：
  10
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  儿茶提取物 在 1,1-二苯基-2-苦味酰肼 作用下， 以 丙酮 为溶剂， 反应 24.0h， 以28 mg的产率得到(+)-catechin (6'-8) (+)-catechin
  参考文献：
  名称：

  Chemical studies on antioxidant mechanism of tea catechins: analysis of radical reaction products of catechin and epicatechin with 2,2-Diphenyl-1-picrylhydrazyl

  摘要：

  Tea catechins, an important class of polyphenols. have been shogun to have wide spectrum of antitumor activity believed to be due mainly to their antioxidative effect. In this study the radical scavenging behavior of catechins on 2.2-diphenyl-picrylhydrazyl (DPPH) was studied. Two reaction products of (+)-catechin, and two reaction products of (-)-epicatechin were purified and identified. Their structures were determined on the basis of detailed high-field 1-D and 2-D NMR spectral analysis. Structure elucidation of these products can provide insights into specific mechanisms of antioxidant reactions. A possible mechanism of the formation of reaction products is suggested. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0968-0896(02)00089-5

文献信息

• Chemical studies on antioxidant mechanism of tea catechins: analysis of radical reaction products of catechin and epicatechin with 2,2-Diphenyl-1-picrylhydrazyl
  作者：Shengmin Sang、Xiaofang Cheng、Ruth E. Stark、Robert T. Rosen、Chung S. Yang、Chi-Tang Ho

  DOI：10.1016/s0968-0896(02)00089-5

  日期：2002.7

  Tea catechins, an important class of polyphenols. have been shogun to have wide spectrum of antitumor activity believed to be due mainly to their antioxidative effect. In this study the radical scavenging behavior of catechins on 2.2-diphenyl-picrylhydrazyl (DPPH) was studied. Two reaction products of (+)-catechin, and two reaction products of (-)-epicatechin were purified and identified. Their structures were determined on the basis of detailed high-field 1-D and 2-D NMR spectral analysis. Structure elucidation of these products can provide insights into specific mechanisms of antioxidant reactions. A possible mechanism of the formation of reaction products is suggested. (C) 2002 Elsevier Science Ltd. All rights reserved.