1-dodecyloxy-4-(heptadecafluorooctyl)benzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-dodecyloxy-4-(heptadecafluorooctyl)benzene
• 英文别名: 1-dodecyloxy-4-heptadecafluorooctylbenzene；1-(Dodecyloxy)-4-(heptadecafluorooctyl)benzene；1-dodecoxy-4-(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl)benzene
• 化学式: C₂₆H₂₉F₁₇O
• 分子量: 680.489
• InChiKey: NLCIIPYASVIHCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13.1
• 重原子数：
  44
• 可旋转键数：
  19
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  18

反应信息

• 作为产物：
  描述：

  溴代十二烷 在 铜 、 potassium carbonate 作用下， 以 吡啶 、 N,N-二甲基甲酰胺 为溶剂， 反应 50.0h， 生成 1-dodecyloxy-4-(heptadecafluorooctyl)benzene
  参考文献：
  名称：

  1-Dodecyloxy-4-perfluoroalkylbenzene as a Novel Efficient Additive in Aldol Reactions and Friedel−Crafts Alkylation in Supercritical Carbon Dioxide

  摘要：

  [GRAPHICS]1-Dodecyloxy-4-perfluoroalkylbenzenes accelerated organic reactions such as aldol-type reactions and Friedel-Crafts alkylation in supercritical carbon dioxide. The perfluoroalkylbenzene worked as a surfactant in the system, and formation of emulsions during the reactions was observed.

  DOI：

  10.1021/ol0173127
• 作为试剂：
  描述：

  反式肉桂醛 、 1-ethoxy-1-(tert-butyldimethylsilyloxy)ethene 在 scandium tris(trifluoromethanesulfonate) 、 1-dodecyloxy-4-(heptadecafluorooctyl)benzene 作用下， 以 二氧化碳 为溶剂， 50.0 ℃ 、8.0 MPa 条件下， 反应 3.0h， 以99%的产率得到(E)-ethyl 3-hydroxy-5-phenylpent-4-enoate
  参考文献：
  名称：

  1-Dodecyloxy-4-perfluoroalkylbenzene as a Novel Efficient Additive in Aldol Reactions and Friedel−Crafts Alkylation in Supercritical Carbon Dioxide

  摘要：

  [GRAPHICS]1-Dodecyloxy-4-perfluoroalkylbenzenes accelerated organic reactions such as aldol-type reactions and Friedel-Crafts alkylation in supercritical carbon dioxide. The perfluoroalkylbenzene worked as a surfactant in the system, and formation of emulsions during the reactions was observed.

  DOI：

  10.1021/ol0173127

文献信息

• 1-Dodecyloxy-4-perfluoroalkylbenzene as a Novel Efficient Additive in Aldol Reactions and Friedel−Crafts Alkylation in Supercritical Carbon Dioxide
  作者：Ichiro Komoto、Shū Kobayashi

  DOI：10.1021/ol0173127

  日期：2002.4.1

  [GRAPHICS]1-Dodecyloxy-4-perfluoroalkylbenzenes accelerated organic reactions such as aldol-type reactions and Friedel-Crafts alkylation in supercritical carbon dioxide. The perfluoroalkylbenzene worked as a surfactant in the system, and formation of emulsions during the reactions was observed.