10-undecenoic acid 2,2,2-trifluoroethanol ester

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 10-undecenoic acid 2,2,2-trifluoroethanol ester
• 英文别名: 10-undecylenic acid 2,2,2-trifluoroethyl ester；2,2,2-Trifluoroethyl undecylenate；2,2,2-trifluoroethyl Undec-10-enoate
• 化学式: C₁₃H₂₁F₃O₂
• 分子量: 266.304
• InChiKey: HBWLCFDIZHOOCG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  18
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  溴代十四烷 、 2,2,2-Trifluoroethyl undec-10-ynoate 、 10-undecenoic acid 2,2,2-trifluoroethanol ester 、 10-十一碳炔酸 、 2-十一烯酸 、 2,2,2-三氟乙醇 、 N,N'-二环己基碳二亚胺 在 4-二甲氨基吡啶 作用下， 以 二甲基亚砜 为溶剂， 生成 11-氟-1-十一碳烯
  参考文献：
  名称：

  Photochemical modification of solid materials

  摘要：

  本发明涉及一种用光化学反应在温和条件下使用烯烃或炔烃来修饰或功能化氧化物表面的过程，例如SiO2和Al2O3表面以及金属，包括不锈钢等合金表面。该过程非常适合形成用于微电子学、生物传感和催化等领域的图案化修饰表面。

  公开号：

  US08993479B2
• 作为产物：
  描述：

  10-十一碳烯基氯酸 、 2,2,2-三氟乙醇 在 吡啶 作用下， 以 苯 为溶剂， 以92%的产率得到10-undecenoic acid 2,2,2-trifluoroethanol ester
  参考文献：
  名称：

  Covalently Attached Monolayers on Crystalline Hydrogen-Terminated Silicon:  Extremely Mild Attachment by Visible Light

  摘要：

  A very mild method was developed for the attachment of high-quality organic monolayers on crystalline silicon surfaces. By using visible light sources, from 447 to 658 nm, a variety of 1-alkenes and 1-alkynes were attached to hydrogen-terminated Si(100) and Si(111) surfaces at room temperature. The presence and the quality of the monolayers were evaluated by static water contact angles, X-ray photoelectron spectroscopy, and IR spectroscopy. Monolayers prepared by thermal, UV light, or visible light initiation were compared. Additionally, the ability of infrared reflection-absorption spectroscopy to study organic monolayers on silicon was explored. A reaction mechanism is discussed on the basis of investigations of the reaction behavior of 1-alkenes with silicon wafers with varying types and levels of doping. Finally, a series of mixed monolayers derived from the mixed solutions of a 1-alkene and an omega-fluorol-alkene were investigated to reveal that the composition of the mixed monolayers was directly proportional to the molar ratio of the two compounds in the solutions.

  DOI：

  10.1021/ja045359s

文献信息

• PHOTOCHEMICAL MODIFICATION OF SOLID MATERIALS
  申请人：Zuilhof Johannes Teunis

  公开号：US20110251059A1

  公开（公告）日：2011-10-13

  The present invention relates to a process for modifying or functionalizing oxide surfaces, such as surfaces of SiO 2 and Al 2 O 3 , but also metals including alloys such as stainless steel with alkenes or alkynes under mild conditions by photochemical reaction. The process is very well suited to form patterned modified surfaces which are of use for example in microelectronics, biosensing and catalysis.

  本发明涉及一种通过光化学反应在温和条件下使用烯烃或炔烃修饰或功能化氧化物表面的方法，例如SiO2和Al2O3表面以及包括不锈钢在内的金属合金表面。该方法非常适用于形成用于微电子学、生物传感和催化等领域的图案化修饰表面。
• Synthesis and Characterization of DNA-Modified Silicon (111) Surfaces
  作者：Todd Strother、Wei Cai、Xinsheng Zhao、Robert J. Hamers、Lloyd M. Smith

  DOI：10.1021/ja9936161

  日期：2000.2.1

  Hydrogen-terminated Si(111) surfaces are modified by attachment of oligodeoxynucleotides and characterized with respect to DNA surface density, chemical stability, and DNA hybridization binding specificity. Surface functionalization employs the reaction of omega-unsaturated alkyl esters with the Si(111) surface using UV irradiation. Cleavage of the ester using potassium tert-butoxide yields a carboxyl-modified surface, which serves as a substrate for the attachment of DNA by means of an electrostatically adsorbed layer of polylysine and attachment of thiol-modified DNA using a heterobifunctional cross-linker. The resultant DNA-modified surfaces are shown to exhibit excellent specificity and chemical stability under the conditions of DNA hybridization. This work provides an avenue for the development of devices in which the exquisite binding specificity of biomolecular recognition is directly coupled to semiconductor devices.
• PROTEIN REPELLING SILICON AND GERMANIUM SURFACES
  申请人：Wageningen University

  公开号：EP2183595A1

  公开（公告）日：2010-05-12
• FUNCTIONALIZED SURFACES AND PREPARATION THEREOF
  申请人：Twist Bioscience Corporation

  公开号：EP3384077A1

  公开（公告）日：2018-10-10
• US8481435B2
  申请人：——

  公开号：US8481435B2

  公开（公告）日：2013-07-09