五缩四乙二醇单烯丙基醚 | 87048-14-4

• 物质功能分类: 材料化学 - 发光材料
• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 五缩四乙二醇单烯丙基醚
• 英文名称: 2-(2-(2-(2-(2-allyloxyethoxy)ethoxy)ethoxy)ethoxy)ethan-1-ol
• 英文别名: 2-(2-{2-[2-(2-allyloxyethoxy)ethoxy]ethoxy}ethoxy)ethanol；1-allylpenta(ethylene glycol)；penta(ethylene glycol) monoallyl alcohol；2-[2-[2-[2-(2-Prop-2-enoxyethoxy)ethoxy]ethoxy]ethoxy]ethanol
• CAS: 87048-14-4
• 化学式: C₁₃H₂₆O₆
• 分子量: 278.346
• InChiKey: BYIRKHZKEMUBMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  19
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  66.4
• 氢给体数：
  1
• 氢受体数：
  6

制备方法与用途

五缩四乙二醇单烯丙基醚是一种醚类有机化合物，可用作离子液体中的光电材料。

反应信息

• 作为反应物：
  描述：

  五缩四乙二醇单烯丙基醚 在 dirhodium tetraacetate sodium hydride 、 N,N-二甲基苯胺 、 三乙胺 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 17.0h， 生成 (Z)-3,9,12,15,18,21,24-heptaoxatricyclo[24.4.0.0^5,7]triaconta-1(26),27,29-trien-4-one
  参考文献：
  名称：

  分子内环丙烷化和叶立德形成的聚醚大环化合物。催化剂的作用和配位

  摘要：

  通过防止进入分子内插入的γ-CH位，已经实现了将催化金属卡宾方法与重氮基乙酸盐用于高收率环尺寸大于25的聚醚大环化合物的构建。环丙烷化是用（II）催化剂进行反应的唯一结果，无需使用溶剂进行高稀释即可获得高于70％的产物收率。使用具有多个用于聚醚配位的位点的铜（I）催化剂，在末端氧处形成分子内氧鎓叶立德，随后与环丙烷化竞争，侧链烯丙基的[2,3]-σ重排。钠离子与反应物重氮化合物的配位抑制了铜催化反应中叶立德鎓盐的形成。

  DOI：

  10.1021/jo0614902
• 作为产物：
  描述：

  烯丙基羟乙基醚 在 sodium hydride 、 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 13.5h， 生成 五缩四乙二醇单烯丙基醚
  参考文献：
  名称：

  分子内环丙烷化和叶立德形成的聚醚大环化合物。催化剂的作用和配位

  摘要：

  通过防止进入分子内插入的γ-CH位，已经实现了将催化金属卡宾方法与重氮基乙酸盐用于高收率环尺寸大于25的聚醚大环化合物的构建。环丙烷化是用（II）催化剂进行反应的唯一结果，无需使用溶剂进行高稀释即可获得高于70％的产物收率。使用具有多个用于聚醚配位的位点的铜（I）催化剂，在末端氧处形成分子内氧鎓叶立德，随后与环丙烷化竞争，侧链烯丙基的[2,3]-σ重排。钠离子与反应物重氮化合物的配位抑制了铜催化反应中叶立德鎓盐的形成。

  DOI：

  10.1021/jo0614902

文献信息

• 一种低泡型有机硅农用助剂及其合成方法
  申请人：浙江工业大学

  公开号：CN110583642A

  公开（公告）日：2019-12-20

  本发明公开了一种低泡型有机硅农用助剂及其合成方法，所述的低泡型有机硅农用助剂为聚醚酯改性有机硅氧烷，所述聚醚酯改性有机硅氧烷的化学结构式如式(I‑1)所示：式(I‑1)中，n＝4～12之间的数值，取代基R为C1～C6的烷基。本发明提出的聚醚酯改性有机硅氧烷无毒害，可以作为农用助剂使用，为一种低泡型农用助剂，泡沫体积约为传统农用助剂的1/4，更适于机械喷洒，提高效率。
• Processes for the preparation of hydroxyl-containing compounds
  申请人：UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC.

  公开号：EP0478076A2

  公开（公告）日：1992-04-01

  A process for preparing hydroxyl-containing compounds which comprises contacting a carboxylated hydroxyl-containing compound with a metal oxide catalyst under conditions effective to produce the hydroxyl-containing compound.

  一种制备含羟基化合物的工艺，包括将羧化的含羟基化合物与金属氧化物催化剂在有效的条件下接触，以产生含羟基化合物。
• Synthesis and Characterization of Network Type Single Ion Conductors
  作者：Xiao-Guang Sun、Craig L. Reeder、John B. Kerr

  DOI：10.1021/ma035690g

  日期：2004.3.1

  New single ion conductors were synthesized by grafting the allyl group-containing lithium salt, lithium bis(allylmalonato)borate (LiBAMB), onto allyl group-containing comb-branch polyacrylate or polymethacrylate ethers by means of hydrosilylation. The highest ambient temperature conductivity of 3.5 x 10(-7) S cm(-1) was obtained for a polyacrylate ether-based single ion conductor containing eight EO units in the side chain and five EO units in the cross-linking side chain, to which the anion was fixed with a salt concentration of EO/Li = 20. For polyacrylate ether-based single ion conductors, an increase of chain length in both side chains and cross-linking anion chains favors an increase of ionic conductivity. The addition of 50 wt % EC/DMC (1/1, wt/wt) increased the ionic conductivity by more than 2 orders of magnitude due to both the increase in ionic mobility from the liquid phase and the increase in the concentration of free ions from the high dielectric constant of the solvent. The preliminary Li/Li cycling profiles of dry polyacrylate- and polymethacrylate ether-based single ion conductors are encouraging as almost no concentration polarization or relaxation was observed. The observed increase in cell potential with cycling is apparently due to an increase in the interfacial impedance associated with the SEI layer, and the cell failure is accompanied by the decomposition of the ester bond of the polyacrylate backbone.
• Synthetic Analogues of Glycosylphosphatidylinositol-Anchored Proteins and Their Behavior in Supported Lipid Bilayers
  作者：Margot G. Paulick、Amber R. Wise、Martin B. Forstner、Jay T. Groves、Carolyn R. Bertozzi

  DOI：10.1021/ja073271j

  日期：2007.9.1

  Positioned at the C-terminus of many eukaryotic proteins, the glycosylphosphaticlylinositol (GPI) anchor is a posttranslational modification that anchors the modified proteins in the outer leaflet of the plasma membrane. GPI-anchored proteins play vital roles in signal transcluction, the vertebrate immune response, and the pathobiology of trypanosomal parasites. While many GPI-anchored proteins have been characterized, the biological functions of the GPI anchor have yet to be elucidated at a molecular level. We synthesized a series of GPI-protein analogues bearing modified anchor structures that were designed to dissect the contribution of various glycan components to the GPI-protein's membrane behavior. These anchor analogues were similar in length to native GPI anchors and included mimics of the native structure's three domains. A combination of expressed protein ligation and native chemical ligation was used to attach these analogues to the green fluorescent protein (GFP). These modified GFPs were incorporated in supported lipid bilayers, and their mobilities were analyzed using fluorescence correlation spectroscopy. The data from these experiments suggest that the GPI anchor is more than a simple membrane-anchoring device; it also may prevent transient interactions between the attached protein and the underlying lipid bilayer, thereby permitting rapid diffusion in the bilayer. The ability to generate chemically defined analogues of GPI-anchored proteins is an important step toward elucidating the molecular functions of this interesting post-translational modification.
• CHESTER, T. L.;BOWLING, D. J.;INNIS, D. P.;PINKSTON, J. D., ANAL. CHEM., 62,(1990) N3, C. 1299-1301
  作者：CHESTER, T. L.、BOWLING, D. J.、INNIS, D. P.、PINKSTON, J. D.

  DOI：——

  日期：——