7-(1,3-diphenylprop-2-ynylidene)bicyclo<2.2.1>heptane

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 7-(1,3-diphenylprop-2-ynylidene)bicyclo<2.2.1>heptane
• 英文别名: 7-(1,3-Diphenylprop-2-ynylidene)bicyclo[2.2.1]heptane
• 化学式: C₂₂H₂₀
• 分子量: 284.401
• InChiKey: LGKWVOAOCKRUEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-氯乙炔基苯 、 环己烯 在 palladium diacetate 、 苄基三乙基氯化铵 、 sodium formate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 48.0h， 以13%的产率得到7-(1,3-diphenylprop-2-ynylidene)bicyclo<2.2.1>heptane
  参考文献：
  名称：

  The First Heck Reactions with 1-Chloroalk-1-ynes: Syntheses of Enynes with Isolatedand Conjugated p-Systems

  摘要：

  The Heck reaction between 1-chloro-2-phenylacetylene and cycloalkenes or cycloalkadienes affords phenylethynyl substituted cycloalkenes as regular Heck products as well as 1,3-diphenylprop-2-ynylidene and (cycloalkenyl)phenylmethylidene substituted bicyclic compounds as tandem products by reaction of ClC=CPh and the cycloalkene in a ratio of 1:2 and 2:1, respectively.

  DOI：

  10.1007/pl00010146

文献信息

• Weigelt, Michael; Becher, Diana; Poetsch, Eike, Journal fur Praktische Chemie (Weinheim), 1999, vol. 341, # 5, p. 477 - 486
  作者：Weigelt, Michael、Becher, Diana、Poetsch, Eike、Bruhn, Clemens、Stroehl, Dieter、Steinborn, Dirk

  DOI：——

  日期：——
• The First Heck Reactions with 1-Chloroalk-1-ynes: Syntheses of Enynes with Isolatedand Conjugated p-Systems
  作者：Michael Weigelt、Diana Becher、Dieter Ströhl、Clemens Bruhn、Eike Poetsch、Dirk Steinborn

  DOI：10.1007/pl00010146

  日期：1998.12

  The Heck reaction between 1-chloro-2-phenylacetylene and cycloalkenes or cycloalkadienes affords phenylethynyl substituted cycloalkenes as regular Heck products as well as 1,3-diphenylprop-2-ynylidene and (cycloalkenyl)phenylmethylidene substituted bicyclic compounds as tandem products by reaction of ClC=CPh and the cycloalkene in a ratio of 1:2 and 2:1, respectively.