5-isopropyl-4-methyl-dihydrofuran-2(3H)-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 5-isopropyl-4-methyl-dihydrofuran-2(3H)-one
• 英文别名: 3-methyl-4-i-propyl-γ-butyrolactone；4-Methyl-5-propan-2-yloxolan-2-one
• 化学式: C₈H₁₄O₂
• 分子量: 142.198
• InChiKey: VZCKPIXXIZDDDT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  巴豆酸甲酯 、 异丁醛 在 samarium diiodide 作用下， 以 四氢呋喃 、 叔丁醇 为溶剂， 反应 5.0h， 生成 5-isopropyl-4-methyl-dihydrofuran-2(3H)-one
  参考文献：
  名称：

  An asymmetric, SmI2-mediated approach to γ-butyrolactones using a new, fluorous-tagged auxiliary

  摘要：

  A new, fluorous-tagged chiral auxiliary has been developed for the asymmetric, SmI2-mediated coupling of aldehydes and alpha,beta-unsaturated esters. gamma-Butyrolactones are obtained in moderate to good isolated yield and in high enantiomeric excess. The fluorous tag allows the auxiliary to be conveniently recovered by fluorous solid-phase extraction (FSPE) and reused. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.08.110

文献信息

• Wang, Siu Ling B.; Su, Jing; Wulff, William D., Journal of the American Chemical Society, 1992, vol. 114, # 26, p. 10665 - 10666
  作者：Wang, Siu Ling B.、Su, Jing、Wulff, William D.、Hoogsteen, Karst

  DOI：——

  日期：——
• Shono, Tatsuya; Matsumura, Yoshihiro; Kashimura, Shigenori, Journal of Chemical Research, Miniprint, 1984, # 7, p. 1922 - 1935
  作者：Shono, Tatsuya、Matsumura, Yoshihiro、Kashimura, Shigenori

  DOI：——

  日期：——
• YAMAGUCHI, MASAHIKO;HIRAO, ICHIRO, CHEM. LETT., 1985, N 3, 337-338
  作者：YAMAGUCHI, MASAHIKO、HIRAO, ICHIRO

  DOI：——

  日期：——
• PHOTORESIST COMPOSITION, COMPOUND, AND PRODUCTION METHOD THEREOF
  申请人：JSR CORPORATION

  公开号：US20150004545A1

  公开（公告）日：2015-01-01

  A photoresist composition containing (A) a polymer having a structural unit (I) that includes an acid-labile group, and (I) a compound represented by the following formula (1). In the following formula (1), R 1 , R 2 , R 3 and R represent a hydrogen atom or a monovalent organic group having 1 to 20 carbon atoms. X represents a single bond, an oxygen atom or —NR a —. R a represents a hydrogen atom, a hydroxy group or a monovalent organic group having 1 to 20 carbon atoms, and optionally taken together represents a ring structure by binding with R each other. A − represents —SO 3 − or —CO 2 − . M + represents a monovalent onium cation.
• US9477149B2
  申请人：——

  公开号：US9477149B2

  公开（公告）日：2016-10-25